JER [Journal of Exercise Rehabilitation]

간행물 정보
  • 자료유형
  • 발행기관
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • ISSN
  • 간기
  • 수록기간
  • 등재여부
  • 주제분류
    의약학 > 재활의학
  • 십진분류
    KDC 514.03 DDC 617.03
Vol.9 No.5 (8건)



New horizon for the therapeutic modality of exercise on neuropsychiatric disorders

Chang-Ju Kim

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.449-450

※ 원문제공기관과의 협약에 따라 개인회원에게 무료로 제공됩니다.

In our studies, treadmill exercise enhanced neurogenesis with increment of serotonin expression, which resulted in improvement of depressive symptoms (Baek et al., 2012). Treadmill exercise alleviated aging-induced memory impairment by enhancing neurogenesis (Kim et al., 2010). Kim et al. (2013) reported that exercise also accelerated maturation of neurons under the brain inflammatory conditions. These therapeutic efficacies of treadmill exercise can be ascribed to the enhancing effect of exercise on neurogenesis. Thus, the enhancing effect of exercise on neurogenesis may open new horizon for the treatment of many neuropsychiatric disorders.

Original Article


Treadmill exercise alleviates prenatal noise stressinduced impairment of spatial learning ability through enhancing hippocampal neurogenesis in rat pups

Tae-Woon Kim, Mal-Soon Shin, Joon-Ki Park, Mi-Ai Shin, Hee-Hyuk Lee, Sam-Jun Lee

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.451-456

※ 기관로그인 시 무료 이용이 가능합니다.

Stress alters brain cell properties and then disturbs cognitive processes, such as learning and memory. In this study, we investigated the effect of postnatal treadmill exercise on hippocampal neurogenesis and spatial learning ability of rat pups following prenatal noise stress. The impact of exercise intensity (mild-intensity exercise vs heavy-intensity exercise) was also compared. The pregnant rats in the stress-applied group were exposed to a 95 dB supersonic machine sound for 1 h once a day from the 15th day after mating until delivery. After birth, the rat pups in the exercise groups were made to run on a treadmill for 30 min once a day for 7 consecutive days, starting 4 weeks after birth. The spatial learning ability was tested using radial-arm maze task and hippocampal neurogenesis was determined by 5-bromo-2’-deoxyuridine (BrdU) immunohistochemistry. The rat pups born from the stress-applied maternal rats spent more time for the seeking of water and showed higher number of error in the radial-arm maze task compared to the control group. These rat pups showed suppressed neurogenesis in the hippocampus. In contrast, the rat pups performed postnatal treadmill exercise saved time for seeking of water and showed lower number of error compared to the stress-applied group. Postnatal treadmill exercise also enhanced neurogenesis in the hippocampus. The mild-intensity exercise showed more potent impact compared to the heavy-intensity exercise. The present results reveal that postnatal treadmill exercise lessens prenatal stress-induced deterioration of brain function in offspring.



Short-term treadmill exercise preserves sensory-motor function through inhibiting apoptosis in the hippocampus of hypoxic ischemia injury rat pups

Jun-Ho Choi, Tae-Soo Kim, Joon-Ki Park, Young-Je Sim, Kijeong Kim, Sam-Jun Lee

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.457-462

※ 기관로그인 시 무료 이용이 가능합니다.

Perinatal hypoxic ischemia injury is a common cause of morbidity and mortality in neonates. Physical exercise may ameliorate neurological impairment by impeding neuronal loss following various brain insults. In the present study, the effect of treadmill exercise on sensory-motor function in relation with hippocampal apoptosis following hypoxic ischemia brain injury was investigated. Sensory-motor function was determined by walking initiation test and apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining and caspase-3 immunohistochemistry. On postnatal 7 day, left common carotid artery of the neonatal rats was ligated for two hours and then the neonatal rats were exposed to hypoxia conditions for one hour. The rat pups in the exercise groups were forced to run on a motorized treadmill for 30 min once a day for 10 days, starting 22 days after induction of hypoxic ischemia brain injury. Hypoxic ischemia caused sensory-motor disturbance with enhancement of apoptosis in the hippocampus. Short-term treadmill exercise suppressed hypoxic ischemia injury-induced apoptosis in the hippocampus, and preserved sensory-motor function of hypoxic ischemia injury rat pups.



The impact of duration of one bout treadmill exercise on cell proliferation and central fatigue in rats

Sang-Won Lee, Yeon-Soo Kim, Tae-Won Jun, Jin-Hee Seo, Kijeong Kim, Mal-Soon Shin, Chang-Ju Kim

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.463-469

※ 기관로그인 시 무료 이용이 가능합니다.

The purpose of this study was to investigate the impact of the dura-tion-dependence of the one bout treadmill exercise on cell proliferation, stress, and central fatigue in rats. The animals were randomly divided into five groups: the non-exercise group, 1-h exercise group, 2-h exer-cise group, 4-h exercise group, and 6-h exercise group. The exercise load consisted of running at speed of 13 meters/min with the 0° inclina-tion. Cell proliferation in the hippocampal dentate gyrus was increased in response to one bout moderate treadmill exercise in all exercise groups. But there was no statistical significance between the exercise duration and cell proliferation. The optical density of glucocorticoid (GR)-positive cells in the hippocampal dentate gyrus was not changed by treadmill exercise at any exercise duration. Expressions of serotonin (5-hydroxytryptamine, 5-HT) and tryptophan hyroxylase (TPH) were in-creased by treadmill exercise only at 6 h duration. It seemed like that there was no additional benefits on cell proliferation over 2 h exercise due to stressful factors with over exercise dose, and there was no change of GR expression due to early assessment point of time. It can be sug-gested that the one-bout of moderate treadmill exercise increased cell proliferation, but treadmill exercise prolonged to 6 h induced central fa- tigue in rats.



Diabetes reduces the cognitive function with the decrease of the visual perception and visual motor integration in male older adults

Hyo-Soon Yun, Eunhwi Kim, Soon-Rim Suh, Mi-Han Kim, Hong Kim

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.470-476

※ 기관로그인 시 무료 이용이 가능합니다.

This study investigated the influence of diabetes on cognitive decline between the diabetes and non- diabetes patients and identified the as-sociations between diabetes and cognitive function, visual perception (VP), and visual motor integration (VMI). Sixty elderly men (67.10±1.65 yr) with and without diabetes (n=30 in each group) who were surveyed by interview and questionnaire in South Korea were enrolled in this study. The score of Mini-Mental State Examination of Korean version (MMSE-KC), Motor-free Visual Perception Test-Vertical Format (MVPT-V), and Visual-Motor Integration 3rd Revision (VMI-3R) were assessed in all of the participants to evaluate cognitive function, VP, and VMI in each. The score of MMSE-KC in the diabetic group was significantly lower than that of the non-diabetes group (P<0.01). Participants in the diabetes group also had lower MVPT-V and VMI-3R scores than those in the non-diabetes group (P<0.01, respectively). Especially, the scores of figure-ground and visual memory among the subcategories of MVPT-V were significantly lower in the diabetes group than in the non-diabetes group (P<0.01). These findings indicate that the decline in cognitive function in individuals with diabetes may be greater than that in non-di-abetics. In addition, the cognitive decline in older adults with diabetes might be associated with the decrease of VP and VMI. In conclusion, we propose that VP and VMI will be helpful to monitor the change of cognitive function in older adults with diabetes as part of the routine management of diabetes-induced cognitive declines.



Objective control skills among students with intellectual disability at special school in Korea

Bog Ja Jeoung

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.477-480

※ 기관로그인 시 무료 이용이 가능합니다.

The purpose of this study was to examine the level of objective control skill and performance criteria of students with intellectual disability at special school. Three hundred thirty one students with intellectual dis-ability were participated this study (M: 230, F: 101). Their aged was from 10-18 aged old. We had the test the objective control skill by video, ob-jective control skill consisted of overhand throwing, catching, kicking, hitting, dribbling. Data were analyzed using liner regression and calcu-lated mean, standard error, standard deviation and 95% confidence in-terval. Total objective control skill mastery was 47%, and hitting skill score was the highest than another subtest, the lowest performance skill was overhand throwing. There were showed that not significant difference object control skill in according to gender. Also not effect ob-ject control skill and subtest in according to age except dribbling. It was showed that significant effect objective control skill in according to dis-ability level.



Effects of peripheral injury in athletes with long-term-exercise participation in modern pentathlons

Bo-Ae Lee, Seung-Hyun Lee, Deuk-Ja Oh

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.481-488

※ 기관로그인 시 무료 이용이 가능합니다.

This study was conducted to verify the effect of the ankle injury of ath-letes who attended the modern pentathlon for a long-term basis on an-kle muscle’s strength and proprioceptive sensory function. For this, 10 athletes of the modern pentathlon, with experience of having damaged one side of their ankles within 6 months, and 10 healthy male college students, who have similar personal characteristics, such as height, age, and weight and have no experience of participating in regular sports for 3 or more times a week. The experimental subject was divid-ed into 3 groups in all. After the flexor power of the plantar and dorsal side and the muscle strength of the varus and valgus for an ankle were measured by the Biodex System III at an angular velocity of 60°/sec and 120°/sec, it was documented as the maximum couple of force per body weight. Also, specified receptive senses were measured by the Biodex System III using the stop button to find the position (angle) of the joint. As a result of the conclusive research, participation in modern pentath-lons for a long-term basis has caused an increase in valgus muscle strength and flexor power of the plantar side of the ankle when com-pared to general college students. Sports-related injury of the ankle was also found to result into the weakening of the flexor power on the plantar side and valgus muscle strength and a decrease of the proprio-ceptive sensory function.



Clinical usefulness of the virtual reality-based postural control training on the gait ability in patients with stroke

Yu-Hyung Park, Chi-ho Lee, Byoung-Hee Lee

한국운동재활학회 JER Vol.9 No.5 2013.10 pp.489-494

※ 기관로그인 시 무료 이용이 가능합니다.

This study is a single blind randomized controlled trial to determine the effect of virtual reality-based postural control training on the gait ability in patients with chronic stroke. Sixteen subjects were randomly as-signed to either experimental group (VR, n=8) or control group (CPT, n= 8). Subjects in both groups received conventional physical therapy for 60 min per day, five days per week during a period of four weeks. Sub-jects in the VR group received additional augmented reality-based train-ing for 30 min per day, three days per week during a period of four weeks. The subjects were evaluated one week before and after participating in a four week training and follow-up at one month post-training. Data de-rived from the gait analyses included spatiotemporal gait parameters, 10 meters walking test (10 mWT). In the gait parameters, subjects in the VR group showed significant improvement, except for cadence at post- training and follow-up within the experimental group. However, no obvi-ous significant improvement was observed within the control group. In between group comparisons, the experimental group (VR group) showed significantly greater improvement only in stride length compared with the control group (P<0.05), however, no significant difference was ob-served in other gait parameters. In conclusion, we demonstrate signifi-cant improvement in gait ability in chronic stroke patients who received virtual reality based postural control training. These findings suggest that virtual reality (VR) postural control training using real-time informa-tion may be a useful approach for enhancement of gait ability in pa-tients with chronic stroke.


페이지 저장