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JER [Journal of Exercise Rehabilitation]

간행물 정보
  • 자료유형
    학술지
  • 발행기관
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • ISSN
    2288-176X
  • EISSN
    2288-1778
  • 간기
    격월간
  • 수록기간
    2013~2018
  • 등재여부
    KCI 등재,SCOPUS
  • 주제분류
    의약학 > 재활의학
  • 십진분류
    KDC 514.03 DDC 617.03
Vol.12 No.5 (21건)
No

Editorial

1

2016 Autumn Conference of the Korean Society of Exercise Rehabilitation

Chang-Ju Kim

한국운동재활학회 JER Vol.12 No.5 2016.10 p.379

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Review Article

2

Role of exercise on the brain

Seung-Soo Baek

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.380-385

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The functions of adult hippocampal neurogenesis have been extensive-ly investigated during the past decade. Numerous studies have shown that adult neurogenesis may play an important role in the hippocam-pal-dependent learning and memory. This study evaluated the influence of exercise on hippocampal neurogenesis, neural plasticity, neuro-trophic factors, and cognition. Areas of research focused on enhancing effect of exercise for adult hippocampal neurogenesis and protective role of exercise against brain diseases. The present study suggests that exercise improves brain functions and prevents decline of cognition across the lifespan. Understanding of neurobiological mechanisms of exercise on brain functions may lead to the development of novel ther-apeutic strategy for neurodegenerative disorders.

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3

Caregiver’s burden in pulmonary arterial hypertension : a clinical review

Sameer Verma, Abhineet Sayal, V. K. Vijayan, Syed M.Rizvi, Arunabh Talwar

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.386-392

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Caregiver’s burden is a multidimensional phenomenon affecting care-givers physically, emotionally and socially. It is critical to examine the burden of caregivers, because of the complex responsibility they have with their partners. There are relatively few studies that have examined factors linked with psychological burden amongst caregivers of pulmo-nary arterial hypertension (PAH) patients. Hence, it is pertinent to devel-op a good understanding of these factors and develop appropriate management strategies, modified to assist PAH caregivers.

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Original Article

4

The morphological and functional effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats

Camila Mayumi Martin Kakihata, Jéssica Aline Malanotte, Jhenifer Karvat, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Gladson Ricardo Flor Bertolini

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.393-400

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The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve com-pression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), trained+lesion (TL), lesion+exercise (LE), and training+le-sion+exercise (TLE), who underwent right sciatic nerve compression on day 21 of the experiment. The TL and TLE groups were submitted to a jumping exercise in a water environment for 20 days prior to injury and the LE and TLE groups after injury. The functional analysis was carried out using the sciatic functional index (SFI). On the last day of the experi-ment, the right sciatic nerves were collected, processed and analysed according to morphology and morphometry. The C group showed high-er SFI in relation to the other groups. In the morphometric analysis, in comparison to C, all groups showed a decrease in the diameter of the injured nerve fibre, the myelin sheath and an increase in the percent-age of connective tissue. There was a decrease in axon diameter in L, TL, and LE groups and a decrease in the density of nerve fibres in the TL and LE groups. The exercise did not affect functional recovery. Howev-er, the exercise prior to the injury improved morphology of the nervous tissue, and when performed pre- and postinjury, there was also an im-provement in nerve regeneration, but this was not the case with exer-cise performed after the injury demonstrating worse results.

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5

Delayed voluntary exercise does not enhance cognitive performance after hippocampal injury : an investigation of differentially distributed exercise protocols

Elise Wogensen, Marie Gajhede Gram, Jens Bak Sommer, Christina Rytter Vilsen, Jesper Mogensen, Hana Malá

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.401-412

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Voluntary exercise has previously been shown to enhance cognitive recovery after acquired brain injury (ABI). The present study evaluated effects of two differentially distributed protocols of delayed, voluntary exercise on cognitive recovery using an allocentric place learning task in an 8-arm radial maze. Fifty-four Wistar rats were subjected to either bilateral transection of the fimbria-fornix (FF) or to sham surgery. Twen-ty-one days postinjury, the animals started exercising in running wheels either for 14 consecutive days (FF/exercise daily [ExD], sham/ExD) or every other day for 14 days (FF/exercise every second day [ExS], sham/ExS). Additional groups were given no exercise treatment (FF/not exer-cise [NE], sham/NE). Regardless of how exercise was distributed, we found no cognitively enhancing effects of exercise in the brain injured animals. Design and protocol factors possibly affecting the efficacy of post-ABI exercise are discussed.

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6

The influence of peripheral vision induced by moving people on postural control in healthy adults

Soo-Han Kim, Du-Jin Park

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.413-416

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This study was conducted to examine the influence of the peripheral vi-sion (PV) induced by moving people on postural control in healthy adults. The subjects consisted of 12 healthy adult volunteers (5 males, 7 females) who had been informed of the study purpose and procedure. The visual interventions were composed of three types. PV1 and PV2 were stimulated using a one-way vertical striped pattern and a two-way vertical striped pattern, respectively. To embody the features of moving people reflected in the mirrors, researchers recorded move-ments of people or objects provided by mirrors on video image. In this study, this was named PV3. The subjects were exposed to each of the visual stimuli for 3 min in a random order, and their postural control was then evaluated. All the subjects were allowed to practice once prior to performing the one leg stand test, functional reaching test and body sway test. All the evaluations were made before and after the visual in-tervention, and the subjects rested for 30 min between each interven-tion. PV3 ranked second in before and after differences of trace length and velocity and had no significant difference from PV2, demonstrating that the PV3, as well as PV2, affected the amount and velocity of body sway. In addition, the standard deviation velocity, trace length and ve-locity values of PV3 were higher than the PV1 values. Therefore, the treatment of those who have difficulty with postural control and balance maintenance should take place in a controlled therapeutic environment.

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7

Observation of implied motion in a work of art modulates cortical connectivity and plasticity

Carmen Concerto, Carmenrita Infortuna, Ludovico Mineo, Manuel Pereira, David Freedberg, Eileen Chusid, Eugenio Aguglia, Fortunato Battaglia

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.417-423

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Following the discovery of mirror neurons, much attention has been de-voted to understanding the neural responses evoked by observation of implied motion in works of art. Neuroimaging studies have demonstrat-ed that dorsal premotor cortex (PMd) is commonly involved during ob-servation of movements but the role of the inhibitory and excitatory connections between PMd and primary motor cortex (M1) during ob-servation of implied motion remains uncertain. In this study, using high and low frequency repetitive transcranial magnetic stimulation (rTMS), we examined PMd–M1 connectivity and plasticity during observation of Michelangelo’s frescos with and without implied motion (Sistine Chapel, 1508–1512). We found that observation of implied motion in a painting specifically reduces the activity of inhibitory PMd–M1 connec-tions. On the contrary PMd–M1 facilitatory connections, as examined by means of 5-Hz rTMS, were not modulated during observation of the painting. Our data suggest that observation of implied motion in a paint-ing modulates PMd–M1 connectivity and plasticity. These results are consistent with the hypothesis that art with implied motion might be used as a plasticity-based intervention in rehabilitation.

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The effect of resistance exercise direction for hip joint stabilization on lateral abdominal muscle thickness

Ju-Hyeon Jung, Sang-Yeol Lee

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.424-428

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The aim of this study was to determine the effects of resistance direc-tion in hip joint stabilization exercise on change in lateral abdominal muscle thickness in healthy adults. Twenty-six healthy adults were ran-domly allocated to either a hip stabilization exercise by hip straight re-sistance group (n=12) or a hip diagonal resistance group (n=14). The outcome measures included contraction thickness ratio in transversus abdominis (TrA), internal oblique (IO) and external oblique, and TrA lat-eral slide were assessed during the abdominal drawing-in maneuver by b-mode ultrasound. The researcher measured the abdominal muscle thickness of each participant before the therapist began the interven-tion and at the moment intervention was applied. There was a signifi-cant difference in lateral abdominal muscle thickness between the straight resistance exercise of hip joint group and the diagonal resis-tance exercise of hip joint group. Significant differences were found between the two groups in the percentage of change of muscle thick-ness of the TrA (P=0.018) and in the thickness ratio of the TrA (P=0.018). Stability exercise accompanied by diagonal resistance on the hip joint that was applied in this study can induce automatic contraction of the IO and TrA, which provides stability to the lumbar spine.

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9

Assessment of isokinetic muscle function in Korea male volleyball athletes

Chang-Gyun Kim, Bog Ja Jeoung

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.429-437

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Volleyball players performed numerous repetitions of spike actions, which uses and requires strong and explosive force, and control of the muscles of the shoulder, lower back, and legs. Muscle imbalance is one of the main causes of sport injuries. The purpose of this study was to assess isokinetic muscle functions in male volleyball players. We thus aim to accurately evaluate their muscle functions, and identify the best training strategy to achieve optimal muscle strength balance in future training programs. The participants in this study consisted of 14 male volleyball players. Muscle strength was measured using the isokinetic dynamometer. Muscle strength was evaluated in terms of peak torque and average power, calculated from five repeated measurements at an angular speed of 60º/sec. Three players who were left attackers showed shoulder imbalance, four players showed trunk joint imbalance, nine players had knee joint of extension/flexion imbalance and four players showed left/right imbalance. The results showed that the num-ber of volleyball players with differences between the strength of the bi-lateral knee muscles, and between the strength of the hamstrings and quadriceps muscles was higher than the number of players with differ-ences between the strength of the shoulder internal and external rota-tion muscles, and higher than the number of players with differences between the strength of the lower back extension and flexion muscles.

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The effects of changing angle and height of toilet seat on movements and ground reaction forces in the feet during sit-to-stand

Su-Kyoung Lee, Sang-Yeol Lee

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.438-441

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The study aimed to examine the effects of changes in the angle and height on movements and ground reaction forces in the feet. Subjects were instructed to sit and stand on different angles and heights; 0° (43 cm), 10° (51 cm), and 15° (58 cm). The motion required in this study is similar to that of standing up from sitting on a chair. The Tumble Forms Wedges (10° [8 cm], 15° [15 cm]) were placed on the toilet seat to cre-ate angles and heights at 0° (43 cm), 10° (51 cm), and 15° (58 cm). The side-to-side travel distances when the subjects stood up from sitting were 103.70±12.46 at 0° (43 cm), 96.99±12.11 at 10° (51 cm), and 99.12±12.00 at 15° (58 cm). The forward and backward travel distances when the subjects stood up from sitting were 235.93±10.60 at 0° (43 cm), 194.17±8.07 at 10° (51 cm), and 181.63±8.66 at 15° (58 cm). The ground reaction forces when the subjects stood up from sitting were 1.09±0.02 at 0° (43 cm), 1.08±0.22 at 10° (51 cm), and 1.07±0.21 at 15° (58 cm). Increases in the angle and height of the toilet seat affected for-ward-and-backward swaying during standing up, but did not affect the ground reaction force and side-to-side swaying.

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11

Effect of concurrent resistance and sprint training on body composition and cardiometabolic health indicators in masters cyclists

Luke Delvecchio, Peter Reaburn, Gail Trapp, Marko T. Korhonen

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.442-450

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In older previously sedentary individuals endurance training imposes a more effective stimulus to enhance cardiometabolic health compared with resistance or sprint training. We examined the effect of replacing a portion of endurance training with combined resistance and/or sprint training and how this influences cardiometabolic health indicators in masters endurance cyclists. Twenty-seven well-trained male road cy-clists (53.7±8.2 years) were allocated to a resistance and track sprint- cycling training group (RTC, n=10), an endurance and track sprint-cy-cling group (ETC, n=7) or a control endurance group (CTRL, n=10). Both the RTC and ETC groups completed a 12-week intervention of spe-cific training while the CTRL group maintained their endurance training load. Lower limb lean mass (LLM), trunk fat mass (TFM), fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured be-fore and after the intervention period. TFM decreased for all groups (P<0.05) while LLM significantly increased for RTC and ETC groups (P<0.05). No significant between group or time effects were observed for FBG, TC, TG, SBP, or DBP. The results suggest that replacing a por-tion of endurance training with 12 weeks of ETC or RTC training favour-ably affects body composition by lowering TFM and increasing LLM without negatively affecting cardiometabolic health indicators in well-trained masters endurance cyclists.

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12

Effect on the parameters of the high-heel shoe and transfer time of ground reaction force during level walking

Seung-Hyun Hyun, Young-Pyo Kim, Che-Cheong Ryew

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.451-455

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This study aimed to analyze an effect on the parameters of high-heel shoe and transfer time of ground reaction force during level walking and subjects participated were composed of adult female subjects (n=13) of 20s with height of high heel (0 cm, 9 cm, respectively). Instru-ment used for the study was 1 set force plate (AMTI-OR9-7) and sam-pling rate for data collection of analysis parameters was set-up at 1,000 Hz. The revelation of required coefficient of friction (RCOF) maximum showed significant difference with more rapid than that of 1st peak ver-tical force (1 PVF). Transfer time of body weight showed significant dif-ference with more delay at 9 cm than that of 0 cm. RCOF required more frictional force required because PVF showed significant difference with larger value on 9 cm than that of 3 cm at 1 PVF. Both center of pressure (COP) x and COPy showed rather less displacement on 9 cm than that of 0 cm. In addition, level walking by high heel shoe did not control efficiently the ground reaction force due to restricted control capacity of coefficient of frictional force and therefore could suggest an inducement of muscle fatigue, heightening a possibility of sliding and falling due to decrease of frictional force.

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13

Longer application of kinesio taping would be beneficial for exercise-induced muscle damage

Jooyoung Kim, Seunghwan Kim, Joohyung Lee

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.456-462

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Kinesio taping (KT) has been widely used to prevent muscle pain and to improve range of motion in clinical settings. However, no previous re-search has examined how long KT should be applied to muscle follow-ing damaging exercise. The aim of this study was to investigate the ef-fect of the duration of KT application on markers of muscle damage fol-lowing eccentric exercise. Thirty-two male subjects participated in the study and were randomly assigned to one of the following groups: con-trol (CON), KT-post, KT-30 min, or KT-24 hr. Eccentric exercise consisted of 2 sets of 25 contractions of elbow flexors using the non-dominant arm. Maximal isometric strength, muscle soreness (SOR), range of mo-tion, and creatine kinase activity were measured before,immediately after, and at 24, 48, 72, and 96 hr after exercise. The KT-24 hr group showed lesser muscle damage and a faster recovery time than the CON and KT-post groups. Both the KT-30 min and KT-24 hr groups showed lesser SOR than CON and KT-post groups. These findings sug-gested that prolonged application of KT had a positive effect on mark-ers of muscle damage.

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The effects of strength exercise and walking on lumbar function, pain level, and body composition in chronic back pain patients

Jung-Seok Lee, Suh-Jung Kang

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.463-470

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The beneficial effects of a strength exercise program and a combined exercise program of strength training plus walking were examined in overweight with chronic back pain patients. The participants were ran-domly placed in the strength exercise group (SEG, n=15), combined ex-ercise group (CEG, n=15), and control group (CG, n=6). All subjects performed exercise twice per week, 50 min per session with a profes-sional instructors for 12 weeks. In order to evaluate exercise interven-tion effects, lumbar function was measured by back strength and flexi-bility. Roland-Morris disability questionnaire (RMDQ) and visual ana-logue scale (VAS) were used to evaluate pain level. Fat and muscle mass were measured to compare body composition changes. All mea-surements were performed before and after 12 weeks of exercise pro-gram. Lumbar function: Back strength was significantly different over time, and significant time×group differences were found between SEG and CG and, CEG and CG. Pain disorder degree: VAS showed a signifi-cant group difference, and significant time×group differences were shown between SEG and CG, and CEG and CG. Also, RMDG showed a significant difference between CEG and CG. Body composition: Fat mass was significantly different over time×group between SEG and CG. In conclusion, participating in strength and walking exercises were beneficial to improve lumbar function. Also, the combined exercise pro-gram was more effective for reducing pain levels than the strength ex-ercise. Finally, fat mass was reduced in this study and this may play a possible role in the improvement of lumbar function and reduction in low back pain.

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The effect of sling exercise on sagittal lumbosacral angle and intervertebral disc area of chronic low back pain patients

Seung-Bum Lee, Won-Je Cho

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.471-475

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The purpose of this study was to observe the change of lumbosacral angle and intervertebral disc (IVD) area. The study was conducted on chronic low back pain (CLBP) female patients for 12 weeks by operating sling exercise and general physical therapy. The 57 CLBP were divided into 2 groups which, sling exercise group (SEG, n=34) and general physical therapy group (PTG, n=23). The experiment was conducted three times a week for 12 weeks. The lumbosacral angle, which means the angle between the L1–L2 lumbar was measured by plain radiogra-phy. The IVD area, which means the IVD height and volume was mea-sured by magnetic resonance imaging. The pain was measured by vi-sual analogue scale (VAS). As a result, after 12-week exercise, VAS had decreased in all groups. The angle of L3–4 and L4–5 and the height of IVD had increased in SEG. Also, IVD height and volume has more im-proved in SEG compare the PTG. Therefore, the sling exercise is proper treatment for CLBP patients’ recovery because It improve the lumbosa-cral angle and IVD area.

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Postprandial lipoprotein profile in two modes of high-intensity intermittent exercise

Valéria Leme Gonçalves Panissa, Ursula Ferreira Julio, Tiego Aparecido Diniz, Barbara de Moura Mello Antunes, Fabio Santos Lira, Monica Yuri Takito, Emerson Franchini

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.476-482

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The aim of present study was to compare blood lipid postprandial pro-file response in two modes of high-intensity intermittent exercise. Twelve individuals (6 men and 6 women) were submitted to a maximal incremental test (to determine maximal aerobic power [MAP] and V. O2pe-ak [peak oxygen uptake]), high-intensity intermittent all-out exercise (60×8-sec bouts interspersed by 12-sec passive recovery) and fixed high-intensity intermittent exercise (100% maximal aerobic speed, con-sisted of 1-min repetitions at MAP [70 rpm] separated by 1-min of pas-sive recovery). Blood samples were collected pre, immediately, 45 and 90-min postexercise. Serum was analyzed for total cholesterol and its ratio, high-density lipoprotein cholesterol (HDL-c), low-density lipopro-tein cholesterol (LDL-c), very low-density lipoprotein (VLDL) cholesterol, and triacylglycerol (TAG). For TAG there was a main effect of moment with higher values immediately postexercise compared to 45-min postexercise. For VLDL there was a main effect to moment with higher values immediately post exercise than pre and 45-min postexercise; higher values 90-min postexercise than 45-min postexercise. There was no effect for HDL-c, LDL-c, and cholesterol. For area under the curve there was no difference for any variable. Our results indicated that both kinds of acute exercise session lead to no improvement in the acute re-sponse of serum lipid profile of healthy young.

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Effect of startup circuit exercise on derivatives reactive oxygen metabolites, biological antioxidant potential levels and physical fitness of adolescents boys with intellectual disabilities

Chang-Gyun Kim, Jin-Seok Lee

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.483-488

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The purpose of this study was to examine the effect of starup circuit ex-ercise program on derivatives reactive oxygen metabolite (d-ROM) and biological antioxidant potential (BAP) levels and physical fitness of ado-lescents with intellectual disabilities, and to sugesst exercise programs to promote the health and physical development of such adolescents. Twelve students with intellectual disabilities were divided into two groups; circuit exercise group (CE group: n=6; age, 14.83±0.98 years; height, 163.83±5.78 cm; body mass, 67.08±3.32 kg; %Fat, 25.68±2.42), control group (CON group: n=6; age: 15.00±0.63 years; height, 162.33±4.41 cm; body mass, 67.50±3.62 kg; %Fat, 26.96±2.06). The CE group performed the CE program 4 times a week over a 12-week period. The CON group maintained their activities of daily living. The following were measured before and after intervention: physical fitness by before and after the completion of the training programm, and were measured and blood samples were assessed. The results of the study indicate that the 12-week CE program increased significantly physical fitness (P<0.05). Furthermore, This study proved that the CE program improved physical fitness, and reduced the d-ROM levels, and increased the BAP levels of the adolescents with intellectual disabilities. Therefore, it may enhance the health and physical development of adolescents boys with intellectual disabilities.

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The effects of objectively measured physical activity and fitness on fear of falling among Korean older women

Myung Kim, Seung-Kil Lim, Sohee Shin, Jae-Hyun Lee

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.489-493

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We examined the effects of objectively measured physical activity (PA) and physical fitness (PF) on fear of falling (FOF) among older adults. The subjects were 94 Korean females aged 65-79. PA was measured with accelerometers, PF with the senior fitness test and FOF with the Korean Survey of Activities and Fear of Falling in the Elderly. With the subjects’ age, number of chronic conditions, and history of falls included as cor-rection factors, a multiple regression analysis showed that PA (P=0.016) and agility/dynamic balance measured by the 8-foot up-and-go test (UNG) (P=0.001) significantly influenced FOF. The FOF of the slowest UNG quartile was significantly higher than those of other groups (P=0.002). This study concludes that among female older adults agility/dynamic balance as measured by UNG is the main factor impacting FOF and individuals with markedly low UNG tend to have high FOF.

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Effect of a 16-week Pilates exercise program on the ego resiliency and depression in elderly women

Su Yeon Roh

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.494-498

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This study aims to examine the effect of a 16-week Pilates exercise pro-gram on the ego resiliency and depression in elderly women. Before participating in Pilates exercise programs, researcher explained the purpose and the intention of the research to elderly women who were willing to participate in this research. A total of 148 elderly women agreed to participate in the program and they filled in ego resiliency and depression questionnaires. Then, the elderly participated in the 16-week Pilates exercise program and completed the same questionnaires afterwards. Collected data was analyzed by the SPSS ver. 20.0 program and results of paired t-test were as follows; there were statistically sig-nificant differences in all subvariables of the ego resiliency such as self-confidence (t=7.770, P<0.001), communication efficiency (t=2.690, P<0.01), optimistic trait (t=1.996, P<0.05), and anger management (t=4.525, P<0.001) after elderly women participated in the 16-week Pi-lates exercise program, there was a statistically significant difference in depression of elderly women who participated in the 16-week Pilates exercise program (t=-6.506, P<0.001) which was statistically lower than before their participation in the program. Consequently, participat-ing in the Pilates exercise program can help improve the ego-resiliency and alleviate depression of the elderly women.

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20

Effects of therapeutic Tai chi on functional fitness and activities of daily living in patients with Parkinson disease

Hye-Jung Choi

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.499-503

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The purpose of the study is to investigate the effects of therapeutic Tai chi (TTC) on the functional fitness status and activities of daily living (ADL) of patients with Parkinson disease (PD). The participants were clinically stable PDs in Hoehn and Yahr stage 1–2. These patients were randomly assigned to either the TTC group (n=11) or the control (CON) group (n=9). The TTC exercised at the clinic 2 times a week and per-formed home-based activity 1 time per week for 12 weeks. All the PDs were evaluated for functional fitness test and ADL screen before and after the 12-week trial. There was a significant Time × group interaction effect on the arm curl (P<0.01), functional reach (P<0.05), and stand on foot with eyes opened (P<0.05) of the functional fitness as compared to the CON. The results of the functional reach test in the CON worsened significantly during the 12-week intervention in comparison with those of the TTC (P<0.01). Also ADL showed significant changed in TCC (P<0.05). Tai chi training showed good effects on the functional fitness in PDs. This study suggests that further research into the based such as Tai chi intervention must be developed PD’s quality of life in the future.

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21

Combined effect of polymorphisms in type III 5-α reductase and androgen receptor gene with the risk of benign prostatic hyperplasia in Korea

Chung Lyul Lee, Jaegeun Lee, Yong Gil Na, Ki Hak Song

한국운동재활학회 JER Vol.12 No.5 2016.10 pp.504-508

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We evaluated whether type III 5-alpha reductase (SRD5A3; steroid re-ductase 5-alpha 3) polymorphism was associated with susceptibility of benign prostate hyperplasia (BPH) and the combined effects in BPH risk between the type of short tandem repeat (STR) in SRD5A3 and the length of trinucleotide (CAG) repeats in androgen receptor (AR) gene. We compared the length of AC repeats in STR region of SRD5A3 gene and a CAG repeat in AR in 188 BPH patients who underwent transure-thral resection of prostate (TURP) and 98 controls by polymerase chain reaction-based methods. We defined short type was less than 21 cop-ies of AC repeats. The odds ratio for BPH between the men with at least one of short type and with both large types of STR in SRD5A3 gene was 3.10 (95% confidence interval [CI], 1.87–5.16; P=0.000). And BPH was 2.35 times more likely to occur in with less than 23 copies of CAG re-peats than men equal or greater than 23 copies in AR gene (95% CI, 1.18–2.36; P=0.016). The men with the large type of STR and ≥23 copies of CAG repeats have 5.3 times BPH risk compared to the reference group with the at least one of the short type of STR and <23 copies (P<0.000). In conclusion, these results suggest that shorter AC repeats of SRD5A3 gene and shorter CAG repeats of AR gene were associated with an increased risk for BPH. However, the interaction between above two factors was not affected in risk of BPH.

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