Earticle

One of the significant impacts of the coronavirus disease 2019 (COVID-19) pandemic on the economy is the large fluctuations in price levels. Moreover, since 2022, the impact of the Russian-Ukrainian conflict has been superimposed, and global inflationary pressure has increased further. Therefore, the imported inflation pressure faced by China has increased significantly. Hence, this study examines whether there is imported inflation in China and profoundly investigates the transmission path of China’s imported inflation as a breakthrough to complete this study. Imported inflation refers to the phenomenon that, under the condition of an open economy, price changes in the international market lead to inflationary pressures in a country’s domestic economy through commodity and monetary channels. The commodity path is mainly based on changes in asset prices. Specifically, in terms of commodity path, the transmission mechanism of imported inflation is expressed as “changes in foreign market prices → changes in prices of imported commodities → changes in costs and prices in domestic open economic sectors → changes in costs and prices in domestic non-open economic sectors → changes in the general domestic price level”. Another transmission channel is the monetary path, the massive inflow of foreign capital. Inflationary pressure is caused by a passive increase in the money supply caused by the inflow of foreign capital. This study uses monthly data from January 2008 to July 2022 to construct a vector autoregressive (VAR) model and uses the Granger causality test method to analyze deeply the causes of inflation in China. This study uses consumer price index (CPI) and producer price index (PPI) to represent China’s inflation level. Meanwhile, this study selects the CRB index to represent the commodity channel factor of imported inflation. In addition, foreign direct investment (FDI) can reflect the impact of international capital flows on China’s imported inflation. Thus, this study uses FDI to represent the monetary channel factor of imported inflation. Moreover, the impact of different types of international commodity prices on domestic inflation may be inconsistent. Therefore, this study also adopts two sub-indices of the CRB index, namely the CRB primary industrial products sub-index and the CRB metal sub-index for robustness testing. This study carried out the stationarity test of the variables. The method adopted is the ADF test to verify the long-term stable relationship of each time series variable. In this way, this study performs VAR model regression on stationary time series variables. Furthermore, this study uses the Granger causality test to determine the causal relationship between variables and the direction of influence. Results show that the commodity channel factor can predict China’s inflation rate. Conversely, the monetary pathway factor has no predictive power for China’s inflation rate. This result shows that global inflation is mainly imported into China through commodity channels rather than monetary channels. The results of the robustness test again show that the commodity channel factor has a significant impact on China’s inflation. Therefore, China’s inflation presents an import-oriented feature dominated by the commodity channel.

Purpose: This study was designed to investigate the trends in school health research in Korea using probabilistic latent semantic analysis. The study longitudinally analyzed the abstracts of the papers published in 「The Journal of the Korean Society of School Health」 over the recent 17 years, which is between 2004 and August 2020. By classifying all the papers according to the topics identified through the analysis, it was possible to see how the distribution of the topics has changed over years. Based on the results, implications for school health research and educational uses of latent semantic analysis were suggested. Methods: This study investigated the research trends by longitudinally analyzing journal abstracts using latent dirichlet allocation (LDA), a type of LSA. The abstracts in 「The Journal of the Korean Society of School Health」 published from 2004 to August 2020 were used for the analysis. Results: A total of 34 latent topics were identified by LDA. Six topics, which were「Adolescent depression and suicide prevention」, 「Students’ knowledge, attitudes, & behaviors」, 「Effective self-esteem program through depression interventions」, 「Factors of students’ stress」, 「Intervention program to prevent adolescent risky behaviors」, and 「Sex education curriculum, and teacher」were most frequently covered by the journal. Each of them was dealt with in at least 20 papers. The topics related to 「Intervention program to prevent adolescent risky behaviors」, 「Effective self-esteem program through depression interventions」, and 「Preventive vaccination and factors of effective vaccination」 appeared repeatedly over the most recent 5 years. Conclusion: This study introduced an AI-powered analysis method that enables data-centered objective text analysis without human intervention. Based on the results, implications for school health research were presented, and various uses of latent semantic analysis (LSA) in educational research were suggested.

The purpose of this study is to explore the effects of fire officers’ experience of traumatic events and subsequent forest healing on their occupational burnout. The results are as follows: First, the experience of traumatic events, social and psychological healing, and relieving stress by strolling had a significant effect on burnout. The more fire officers are exposed to traumatic events, the more they lose self-control in social and psychological aspects, and the lower the level of stress relieved through strolling, the higher the level of burnout. Thi sresult suggests that the more fire office rsare called out for fire fighting, the more they see their colleagues with severein juries, and the higher the level of mental and physical an xiety, the more they areex hausted. Moreover, for es thealing help store duce the irmental and physi calfatig uecaused by traumatic events, thu spreven ting them from suffering from burn out. Second, the experience of traumatic events, social and psychological healing, and relieving stress by strolling had a significant impact on occupational stress. The more fire officers are exposed to traumatic events, the more they lose self-control in social and psychological aspects, and the lower the level of stress relieved through strolling, the higher the level of occupational stress. This result indicates that to relieve job stress caused by fire fighting, increased forest healing activities, including various programs such as psychotherapy, developing interpersonal relationships and self-control, and creating a positive mind-set, can reducejobstress and help fire officers recover from it. Lastly, job stress had a mediation effect on the effects of the experience of traumatic events and forest healing on burnout. This implies that burnout can be prevented when fire officers gain high emotional stability through social and psychological healing and stress-relief strolling over a traumatic experience, and stronger support from the organization and family can keep them from being emotionally drained, thus contributing to the prevention of burnout.

이 연구는 재한 중국유학생의 대학생활 적응경험에 대하여 심층면담에 의한 질적 연구방법을 활용하여 살펴보았다. 한국에서 대학생활을 하는 중국유학생들은 학업과 경제적인 면에서 가장 큰 어려움을 겪고 있었다. 따라서 이 연구는 중국유학생들이 학업과 함께 아르바이트를 병행하면서 한국 대학과 사회에 적응해 간 경험의 과정은 어떠하며 그 경험의 의미는 무엇인지 분석해 보고자 하였다. 이를 위해 서울에 위치한 A대학에 재학 중인 중국유학생 8명을 대상으로 심층면담을 하여 분석한 결과, 대학생활 적응경험으로 전공수업의 어려움, 친구 사귀기의 한계, 교수와의 관계, 사회․문화적 차이에 당황함, 외로움과 우울, 힘들지만 유익한 아르바이트 경험이라는 여섯 가지 주제로 범주화할 수 있었다. 특히 중국유학생의 아르바이트 경험으로는 차별과 무시, 성희롱과 중국인은 더럽다는 편견, 중국(산)에 대한 불신과 무시, 한국의 직장문화와 인간관계에 대해 배움, 한국의 언어와 문화에 대한 이해, 진로 탐색의 기회를 얻음이라는 하위 주제를 발견할 수 있었다.

This research focuses on the acculturation experiences of the Chinese students studying at South Korea University, specially the academic learning and Arbeit(part-time job) experiences. They have double identity as worker and student. Research method of this paper is based on the qualitative research methods, specially in-depth interviews. 8 Chinese students have attended to in-depth interviews, they are all studying at University A in Seoul. The result of research have identified considerable difficulties that Chinese students have experienced in their academic learning at South Korea University. It has been demonstrated that difficult of Chinese students’academic study, limit of making new friends, sense of loneliness and depression, relationship with faculty, their unfamiliarity with the South Korean culture, working part-time for his school expenses. They have experienced discrimination and ignoring, sexual harassment for girl students, and ignoring and derogatory about Chinese products in the process of part-time job, while have got opportunities for understanding South Korea's workplace culture, for learning about the importance of human relationships, and for searching their job and career exploration.

목적 : 한글판 수정바델지수 체크리스트를 고안하고 기존 한글판 수정바델지수와 신뢰도를 비교 평가하기 위함이다. 연구방법 : 연구대상은 뇌병변 환자 30명을 대상으로 하였다. 한글판 수정바델지수 체크리스트(이하 K-MBI 체크리스트)는 기존의 한글판 수정바델지수(기존 K-MBI)와 수정바델지수(MBI) 원본을 참고하여 각 항목별 평가 내용을 세분화 및 체크리스트화 하였다. 30명의 환자를 대상으로 K-MBI 체크리스트를 사용하는 그룹과 기존 KMBI를 사용하 는 그룹으로 나누어 각 그룹에 2명의 치료사를 배정하였다. 결과분석은 평가자간 신뢰도를 알아보기 위해 총점수준에서 급간내상관계수를 구하였으며, 세부항목 수준에서 카파검정을 시행하였다. 결과 : 총점수준에서의 신뢰도는 K-MBI 체크리스트(ICC= .981)와 기존 K-MBI(ICC= .973)를 사용한 두 그룹 모두에서 매우 높은 검사자간 신뢰도를 보였다(p<.001). 세부항목별 일치도에서는 K-MBI 체크리스트를 사용한 그룹과 기존 K-MBI의 경우 모두 4개 항목에서 탁월한 일치도를 보였다. Mean K값은 K-MBI 체크리스트(.725)가 K-MBI(.699) 보다 높게 나타났다. 결론 : K-MBI 체크리스트와 기존의 K-MBI 모두 총점수준에서 높은 수준의 평가자간 신뢰도를 보였다. 세부항목수준에서 역시 두 그룹 모두 전 항목에서 상당한 수준 이상의 신뢰도를 확보하였으나, 항목 간에는 다소 차이가 있었다.

Objective : The purpose of this study was to devise a checklist version of Korean version of Modified Barthel Index(K-MBI) and compare its reliability with the K-MBI. Methods : The subjects were 30 brain injury patients. We subdivided each subitem of the original K-MBI and created a checklist (so-called K-MBI checklist). We divided it into 2 groups: a newly developed K-MBI checklist, and the original K-MBI, with two randomly assigned occupational therapists for each group. The collected data were analyzed to ascertain the inter-rater reliability through an intraclass correlation coefficient (ICC) for the total test score and Kappa statistics for the subitems of the test. Results : The inter-rater reliability of the total test score was significantly high in both the K-MBI checklist group (ICC=.981) and the original K-MBI group (ICC= .973)(p<.001). For the internal constancy in the subitems of the test, both groups showed excellent reliability in four items. The mean Kappa value was higher in the K-MBI checklist group (.725) than in the original K-MBI group (.699). Conclusions : Both the newly developed K-MBI checklist and original K-MBI showed high consistency in their total scores. In the subitems, the newly developed K-MBI checklist provided higher consistency than the original K-MBI except for dressing subitems. Meanwhile, the K-MBI showed low consistency in personal hygiene and ambulation subitems.

본 연구는 기관투자자 제도, 해외 증시와의 교차거래 제도, A주의 글로벌 지수 편입, 신규 보드 개설 등의 네 가지 측면에서 중국 A주 시장의 대외개방 정책 및 그 성과에 대해 살펴보았으며, 아울러 이러한 A주 시장의 대외개 방 정책이 상하이종합주가지수와 선전종합주가지수에 미치는 영향에 대해 1994년 1월 3일부터 2024년 5월 30일까지 의 시계열 자료를 이용하여 실증적으로 분석하였다. 분석 결과 QFII·RQFII와 같은 기관투자자 제도, 후강퉁·선강퉁과 같은 해외 증시와의 교차거래 제도, A주의 MSCI EM 지수나 FTSE Russell 지수와 같은 글로벌 지수에의 편입, 과 학혁신보드와 같은 신규 보드 개설 등의 모든 대외개방 정책이 주가지수에 통계적으로 유의미한 양의 영향을 미침이 확인되었다. 이러한 분석 결과를 토대로 우리는 중국이 향후 주식시장 대외개방을 더욱 확대해야 하고, 특히 개인투 자자들의 중국 주식시장에 대한 접근성을 더욱 확대해야 하며, 외국과 정치적 갈등을 완화하고 이해를 증진시키기 위 한 상호 노력이 필요하며, 부동산을 비롯한 산업규제 완화가 중국의 경기회복과 외국인의 A주 시장 투자에 긍정적인 영향을 미칠 것이라는 결론을 도출하였다.

This study examined the policy of opening up the Chinese A-share market and its performance in four aspects: institutional investors system, cross-trading system with overseas stock markets, inclusion of A-shares into global indices, and establishment of a new board. Then, the impact of these policies on the Stock Index was empirically analyzed, and it was confirmed that institutional investors system such as QFII and RQFII, cross-trading system with overseas stock markets such as Shanghai-Hong Kong Stock Connect and Shenzhen-Hong Kong Stock Connect, inclusion of A-shares into global indices such as the MSCI EM index and FTSE Russell index, and the establishment of a new board of the Science Innovation Board all had statistically significant positive impacts on the stock index. Based on the results of these analysis, we conclude that China should further expand its stock market opening to the outside world, that mutual efforts are needed to alleviate political conflicts and improve understanding, and that easing industry regulations, including real estate, will help China's economic recovery and foreigners’ investment in the A-share market.

We often hear that “There are classical literatures in well made contents.”and “Classical literatures are golden geese.”It seems that classical literatures work as the treasure houses in creating lots of cultural contents. Currently, there are hot debates on the reform of the obsolete system and innovation in the academic field of Korean literature. With the advent of multi channel era, we all begin to acknowledge the importance of the depth in the interpretations of the classical texts and the emotions and interests that those interpretations could invoke. The recognition of classical literatures as a laminated cultural and spiritual living and close examination of the identities are more important than treating them as a simple source for multi-use and counting their economic values. “Crisis in the humane studies”has implications that literatures are far from practical use and the industrial uses of literature studies are at its early stage. The creation of practical values by literary works and studies should it be measured only with the industrial or economical view point? Can it be done without the complete understanding of the classic texts and those who have enjoyed them? This thesis is based on my presentation and debates that presented on the regular seminar at the Society of Korean Literary Creative Writing. The theme of the seminar was long term interdisciplinary studies on the regional cultures with focus on the groping of methodologies of literary studies and examination of their meanings. This thesis tries to cultivate the insight of evaluating rough gems and reveal the process of transforming the raw ore into one well defined gem. This thesis tries to show the method and direction of creating contents that merge region, culture and literature under the regional storytelling and cultural map. The relationship between literature and regional culture can be said as inseparably coexist. Especially, since classic literatures are writings of the lives and characters of the anciitertimes, they wi live the roots and foundnd foundndregional cultures. Since some are disappeared and transformed, it would be difficult to reconstruct them act. It might end up by simply arranging the data of the old cultural remains and explanations of them. Isn’t there any reflections or problems in the attitude of scholars in studying classic literatures and cultures? Isn’t it that the study of classic works are inactive while the utilization of the works are active? It sometimes seems that characters are symbolized and used simply as means of regional festivals only for economical purposes. These are the issues that I want pursue in this thesis.

유방암 관련 기존 AI 연구는 보조적인 진단 예측이나 임상적 요인에 따른 진료 결과를 예측하는 주제가 많았다. 또한 연구기관의 코호트 자료나 일부 환자 자료를 이용하는 경우가 대부분이었다. 본 논문에서는 건강보험심사평가원이 보유하고 있는 전 국민 유방암 환자의 전수 데이터를 활용하여 유방암 환자의 40~50대와 다른 연령대 간의 생존 여부 예측과 생존 여부에 미치는 요인의 차이점을 분석했다. 그 결과, 환자들의 생존 여부 예측 정밀도는 40~50대가 평균 0.93으로 60~80대 0.86 보다 높았으며, 요인에 있어서도 40~50대는 치료횟수(46%)가, 60~80대는 나이(32%)의 변수 중요도가 제일 높았다. 기존 연구와 성능 비교 결과, 평균 정밀도가 0.90으로 기존 논문의 정밀도 0.81보다 높았다. 적용 알고리즘별 성능 비교 결과, 의사결정나무(Decision Tree), 랜덤포레스트(Random Forest) 및 그래디언트부스팅(Gradient Boosting)의 전체 평균 정밀도는 0.90, 재현율은 1.0으로 연령대 그룹 내에서 동일하였으며, 다층퍼셉트론(Multi-Layer Perceptron)의 정밀도는 0.89, 재현율은 1.0 이었다. 심평원의 전 국민 심사청구 빅데이터 가치 활용을 제고하기 위해 비전문가용 머신러닝 자동화(Auto ML) 도구를 사용한 더 많은 연구가 진행되기를 바란다.

Research using AI and big data is also being actively conducted in the health and medical fields such as disease diagnosis and treatment. Most of the existing research data used cohort data from research institutes or some patient data. In this paper, the difference in the prediction rate of survival and the factors affecting survival between breast cancer patients in their 40~50s and other age groups was revealed using health insurance review claim data held by the HIRA. As a result, the accuracy of predicting patients' survival was 0.93 on average in their 40~50s, higher than 0.86 in their 60~80s. In terms of that factor, the number of treatments was high for those in their 40~50s, and age was high for those in their 60~80s. Performance comparison with previous studies, the average precision was 0.90, which was higher than 0.81 of the existing paper. As a result of performance comparison by applied algorithm, the overall average precision of Decision Tree, Random Forest, and Gradient Boosting was 0.90, and the recall was 1.0, and the precision of multi-layer perceptrons was 0.89, and the recall was 1.0. I hope that more research will be conducted using machine learning automation(Auto ML) tools for non-professionals to enhance the use of the value for health insurance review claim data held by the HIRA.

이 연구는 신문의 뉴스 기사가 '마약 중독'에 대해 어떤 담론을 생산·유통하는지 알아보고, 그 담론의 지형과 의미를 밝히는데 목적이 있다. 이를 위해 국내 4개 일간지 신문의 뉴스기사를 대상으로 '마약', '마약 중독'을 키워드로 검색하여 자료를 수집하였다. 페어클로(Norman Fairclough)의 비판적 담론분석 방법을 활용하여 분석한 결과, 첫째, 텍스트 분석에서 마약 중독은 '범죄-처벌' 담론이 지배적이었다. 마약중독은 사회악이자 성범죄, 아동범죄, 폭력과 같은 중범죄이므로 엄격히 처벌해야 한다는 것이다. 둘째, 담론실천 분석에서 마약 중독은 치료가 필요한 '질병', 즉 정신질환이므로 국가에 의한 체계적 관리가 필요하다. 셋째, 사회문화적 실천 분석에서 마약 중독은 경제적 이익을 목적으로 한 돈벌이 수단이자, 정치권력의 부패와 관련이 있으며, 마약범죄가 국가의 근간을 위협하지 못하도록 강력히 통제해야 할 대상이다. 문화적으로 마약 중독은 쾌락 추구의 동기에서 비롯되며, 도덕적 타락의 결과이다. 이러한 분석을 통해 마약 중독의 지배 담론인 '범죄-처벌' 담론의 한계를 지적하고, '질병-치료' 담론으로의 전환과 치료·재활 중심의 약물정책을 대안으로 제시하였다.

The purpose of this study is to find out what discourse the newspaper's articles produce and distribute about 'drug addiction' and to reveal the topography and meaning of the discourse. Data were collected by searching 'drug' 'drug addiction' as keywords for news articles in four daily newspapers in Korea. As a result of analyzing using Norman Fairclough's critical discourse analysis, first, the 'crime-punishment' discourse was dominant in textual analysis. Drug addiction is a social evil and a serious crime such as sex crimes, child crimes, and violence, so it should be strictly punished. Second, in the discourse practice analysis, drug addiction is a mental disease that needs treatment, so systematic management by the state is required. Third, in the socio-cultural practice analysis, drug addiction is a means of making money for economic benefit, is related to corruption of political power, and is an object that should be strongly controlled to prevent drug crimes from threatening the foundation of the state. Culturally, drug addiction stems from the motivation of pleasure seeking, and is the result of moral degradation. Through this analysis, the conversion to the 'disease-treatment' discourse and drug policies centered on treatment and rehabilitation were suggested as alternatives.

본 연구의 목적은 전문직 자아개념과 감정노동이 이직의도에 미치는 영향을 고찰해보는 것으로서, 감정 노동 상황에 노출되며 전문직 자아개념의 강하게 작용하고 있는 여성아동병원 간호사 대상으로 실증분석을 하였다. 분석결과 전문직자아개념과 감정노동간의 관계에서는 전문직자아개념의 구성요소 중 업무만족감만 감정노동과 통계적으로 유의한 결과로 나타났다. 전문직 자아개념과 이직의도간의 관계에서는 전문직 실무 업무에 대한 자부심과 업무만족감이 이직의도에 유의한 영향을 미치는 것으로 나타났다. 감정노동과 이직 의도간의 관계에서는 감정노동중 표면행위만 이직의도에 정의관계로 유의하게 나타났다. 연구 결과를 토대로, 여성아동병원 간호사처럼 전문성을 지니며 감정노동이 강한 조직구성원의 이직의도를 낮추기 위해서는 전문가로서의 자부심이 강한만큼 전문가로서의 인정 및 업무만족감을 높이기 위한 조직관리방안이 모색되어야 하며, 감정노동의 내면화나 표면행위에 따른 부정성 해소 방안이 적용되어야 할 것이다.

The purpose of this study is to consider the impact on the degree of turnover of the professional self-concept and the emotional labor. This study were subjected to empirical analysis on female children's hospital nurses. The results of the analysis, only emotional labor and task satisfaction among the components of the professional self-concept became statistically significant results. The relationship between professional pride and task satisfaction have a significant effect on turnover. The relationship only of surface acting and turnover between those of emotional labor and turnover became significant. Based on the research results, it should be preferred to nurse specialists in the women's hospital, in order to lower the turnover of nurses. Management strategies of the organization should be sought to improve operational feeling of satisfaction, and Also the approach should be applied to ease the negativity of surface acting.

공학교육에 적용할 목적으로 효율적이고 정확한 개념 습득을 위한 탐구기반 개념학습 모형을 도입하고 이를 지원하는 탐구활동 지원도구를 개발하였다. 또한 이를 실제 교육현장에 적용하기 위하여 Windows 웹기반 응용프로그램인 온라인 학습 커뮤니티를 구축하였다. 여기에는 탐구기반 개념학습의 수업절차를 수행할 수 있도록 탐구활동 메뉴, 구성원 간의 커뮤니케이션 지원 기능, 정보공유 기능, 수업 및 탐구활동 스케쥴링 기능, 멘토링 기능, 온라인 활동 평가 기능 등이 포함되었다. 본 연구에서는 도출된 탐구활동 지원도구의 유용성을 검증하고 탐구활동 지원도구가 공학교육에서의 탐구기반 개념학습에 미치는 영향을 실험연구를 통하여 조사하고자 하였다. 실험연구 결과, 실험집단에게 탐구활동 지원도구를 오프라인 및 온라인으로 제공함으로써 비교집단에 비해 높은 메타인지와 효율적인 학습 수행을 지원하는 것이 가능하였으며 탐구활동을 촉진시킬 수 있음을 확인하였다. 또한, 학습자들의 개념이해능력에 있어서 탐구기반 개념학습의 수업절차, 탐구활동 지원도구, 교수자의 지원활동이 적용된 실험집단이 유의미한 차이를 보이는 것을 확인하였다.

The previously developed practical inquiry activity supporting tools, deduced from the design principles and implementation principles based on the study of precedent researches and theories, applicable to conceptual learning in engineering education were implemented to an on-line learning community, a web-based Windows application, to find out its effectiveness in actual classroom situation through experimental research. The On-line learning community includes the inquiry activity menu to implement learning procedure of inquiry based conceptual learning, the functions supporting the communication among participants, the information sharing function, the scheduling function of class and inquiry activity, the mentoring function, and the evaluation of on-line activities of learners. Experimental study were also conducted in order to analyze the effects of inquiry activity supporting tools on inquiry based conceptual learning in engineering education.

This study was conducted to investigate the relationship between long naming of beverages and its effect on people's perception by gender. The survey was conducted in the Seoul area from March 10 to May 10, 2010. Approximately 59% of male and 41.8% of the female respondents were randomly selected from university students aged 20 to 29-years. Most (79.8%) of the students responding to the survey showed a preference for beverages. "Long-named beverages with ingredients listed" were considered the most reliable and ranked highest at 3.74, A significant difference was observed between males and females. "Long-named beverage that were made from domestic agricultural products" were regarded as the most healthful and ranked highest at 4.01. A significant difference between males and females was also observed. Long-naming influences a customer's purchasing tendency. In particular, women were more influenced by a sense of wellbeing when they purchase, because they are more interested in losing weight and being healthy.

목 적 : 최근 신생아 집중 치료의 발달로 인하여 출생체중 1,500 g 미만의 극소 저체중출생아(very low birth weight infants, VLBWI)의 생존율이 높아지고 있다. 이에 저자들은 최근 12년간 한림대학교 강남성심병원 신생아 중환자실에 입원한 극소 저체중 출생아의 치료 결과의 변화를 조사하였다. 방 법 : 1997년 1월 1일부터 2008년 12월 31일까지 한림대학교 강남성심병원 신생아 중환자실에 입원한 1,500 g 미만의 VLBWI 339명을 대상으로 하였고 I기(1997-2003년), II기(2004-2008년)로 나누어 각기별 출생체중과 재태연령의 변화, 생존율, 이환율, 사망원인 및 시기에 대해 병록지 검토를 통해 후향적으로 조사하였다. 결 과 : VLBWI 발생 빈도는 II기에 유의하게 증가하였으며 평균 출생체중 및 재태 연령도 I기에 비해 II기에 유의하게 감소하였으나 1분과 5분 아프가 점수는 II기에 더 높았고(P<0.05), 인공 호흡기 사용기간, 산소 총 투여 기간에는 두 기간사이의 통계적으로 유의한 차이는 없었다(P>0.05). 산모와의 관계를 보면 자궁경부 근무력증, 출생 전 스테로이드 사용, 조기 양막파수는 II기에 유의하게 증가하였다. 생존율에 있어서는 I기에 59.1%, II기에 74.2%로 유의한 증가를 보였으며(P<0.05), 출생체중 1,000 g 미만, 재태연령 28주 미만의 환아의 생존율 증가가 두드러졌다. 극소 저체중 출생아에서 흔히 동반되는 질환으로는 호흡곤란 증후군, 미숙아 망막증, 패혈증, 기관지폐 형성이상, 동맥관 개존증, grade III 이상의 뇌실 내 출혈 및 뇌백질 연화증, 괴사성 장염의 발생은 동맥관 개존증을 제외하고는 두 기간 간의 유의한 차이는 없었다. 사망 원인으로는 호흡곤란 증후군이 가장 많았고 폐출혈, 패혈증이 그다음을 차지하였고, 사망 시기는 두 기간 모두 7일 이내 사망률이 가장 높았다. 결 론 : 최근 12년간 본원에서 출생한 VLBWI의 생존율은 현저히 향상되었으며 특히 1,000 g 미만 28주 미만 환아에서의 생존율 향상이 두드러졌다. 이는 여러 가지 신생아 집중치료술의 향상에 따른 것으로 생각된다. 하지만, 아직 초기 사망율이 높으므로 급성기 치료에 더욱 관심을 갖고 출생체중, 재태연령, 산소치료등과 밀접한 관계가 있는 합병증인 기관지폐 형성이상, 미숙아 망막증 등의 빈도를 줄이기 위해 노력해야 할 것으로 생각된다.

Purpose : The survival rate of very low birth weight infant (VLBWI) had increased as a result of advances in neonatal intensive care. We evaluated the changes in outcomes of VLBWI who admitted to the neonatal care unit of Hallym University Kangnam Sacred Heart Hospital. Methods : Retrospective review of 339 VLBWI who were born from 1st January 1997 to 31th December 2008 were performed. Outcomes including survival rate, birth weight (BW), gestational age (GA), morbidities, and mortality between period I (1997- 2003) and period II (2004-2008) were compared. Results : Overall incidence of VLBWI was 2.3% and it was significantly higher in period II(3.3%). Mean BW and GA were significantly decreased in period II (P<0.001, P=0.01). The survival rate increased from period I (59.1%) to period II (74.2%). BW-specific survival rate increased in 1,000-1,249 gm and GA-specific survival rate significantly increased in 27-28 weeks and 29-30 weeks. The incidences of respiratory distress syndrome (RDS), retinopathy of prematurity (ROP), sepsis, bronchopulmonary dysplasia (BPD), intraventricular hemorrhage, periventricular leukomalacia, and necorotizing enterocolitis were same except patent ductus arteriosus. Conclusion : The survival rate of VLBWI was increased in period II, especially in less than 1,000 gm and below 27 weeks. This may be due to recent dramatic improvement of neonatal care. But more efforts are needed to improve outcome during initial phase and to reduce long term complication such as BPD and ROP.

5-14세에 호발하는 마이코플라즈마 폐렴은 20-25%에서 폐외 증상을 일으키는 것으로 알려져 있으며 이 중 혈액계 질환에는 용혈성 빈혈, 혈소판 감소증, 혈구포식세포 증식증(hemophagocytosis) 등이 있다. 마이코플라즈마 폐렴에서의 냉항체에 의한 자가면역성 용혈로 용혈성 빈혈이 발생할 수 있으며, 이 때 항체의 역가와 용혈의 정도에 상관관계가 있을 수 있다. 저자들은 마이코플라즈마 폐렴에 의해 용혈성 빈혈이 발현된 유전성 구상 적혈구증 1례를 경험하였기에 보고하는 바이다.

Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in children, with a peak incidence at 5-14 years. Extrapulmonary manifestations occur in 20-25% of patients with M. pneumoniae infection. Most auto-antibodies that cause immune hemolytic anemia in humans are cold agglutinins. The formation of cold agglutinins is frequently observed during M. pneumoniae infections, and cold agglutinin disease usually occurs during M. pneumoniae infections. Nevertheless, severe hemolysis is exceptional. If a patient has any underlying disease related to hemolysis, it is possible to accelerate hemolysis. Hereditary spherocytosis is a common cause of hereditary hemolytic anemia resulting from red blood cell membrane defects. Hemolysis of red cells may result from corpuscular abnormalities or extracorpuscular abnormalities, such as immune or non-immune mechanisms. We report a case of hereditary spherocytosis associated with severe hemolytic anemia due to Mycoplasma pneumonia.

Aminoglycosides are frequently used antibiotics in children. The multiple daily dosing (MDD) in infants and children is twice or three times daily depending on age. Recent studies in adults have shown that once daily dosing (ODD) maximizes the bactericidal activity and might minimize the toxicity of antibiotics. So, I reviewed many studies about efficacy, toxicity and cost effectiveness of ODD of aminoglycosides in children. Most studies suggest that ODD compared with MDD of aminoglycosides is theoretically more efficacious and has no higher toxicity in infants and children. But, the total number of patients included in the studies is not large. Multi-center, controlled prospective studies are required in larger numbers of infants and children to determine the efficacy and safety of the ODD regimen in children before ODD of aminoglycosides can be recommended for routine use.