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1

A Novel Feature Gene Selection Method Based On Neighborhood Mutual Information

Tao Chen, Zenglin Hong, Hui Zhao, Xiao Yang, Jun Wei

보안공학연구지원센터(IJHIT) International Journal of Hybrid Information Technology Vol.8 No.7 2015.07 pp.277-292

※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

DNA microarray technique can detect tens of thousands of genes activity in cells and has been widely used in clinical diagnosis. However, microarray data has characteristics of high dimension and small samples, moreover many irrelevant and redundant genes also decrease performance of classification algorithm .Mutual information is very effective method and has widely been used in feature gene selection, but it cannot directly deal with continuous features. Therefore, this paper proposes a novel feature gene selection method to resolve this problem. Firstly, a lot of irrelevant genes are eliminated from original data by using reliefF algorithm , and the candidate subset of genes is obtained; Secondly, a algorithm based on neighborhood mutual information and forward greedy search strategy which deals with directly continuous features is proposed to select feature genes in above genes subset. Here, because radius of neighborhood greatly affects reduction performance, differential evolution algorithm is applied to optimize radius before reduction. The simulation results on six benchmark microarray datasets show that our method can obtain higher classification accuracy using as few genes as possible, especially neighborhood mutual information can directly continuous features. Feature genes selected has an important meaning for understanding microarray data and finding pathogenic genes of cancer. It is an effective and efficient method for feature genes selection.

2

A Hybrid Feature Gene Selection Method based on Fuzzy Neighborhood Rough Set with Information Entropy

Tao Chen, Zenglin Hong, Fang-an Deng, Man Cui

보안공학연구지원센터(IJSIP) International Journal of Signal Processing, Image Processing and Pattern Recognition Vol.7 No.6 2014.12 pp.95-110

※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

DNA microarray technique can detect tens of thousands of genes activity in cells and has been widely used in clinical diagnosis. However, microarray data has the characteristics of high dimension and small samples, moreover many irrelevant and redundant genes also decrease performance of classification algorithm. Feature gene selection is an effective method to solve this problem. This paper proposes a hybrid feature gene selection method. Firstly, a lot of irrelevant genes from original data were eliminated by using reliefF algorithm, and the candidate feature genes subset is obtained; Secondly, Fuzzy neighborhood rough set with information entropy which deals directly with continuous data is proposed to reduce redundant genes among genes subset above. Here, differential evolution algorithm is used to optimize radius before reduction by using fuzzy neighborhood rough set, because radius of neighborhood greatly affects reduction performance. The simulation results on six microarray datasets indicate that our method can obtain higher classification accuracy by using as few genes as possible, especially feature genes selected are important for understanding microarray data and identifying the pathogenic genes. The results demonstrated that this method is effective and efficient for feature genes selection.

3

Automatic speaker verification (ASV) systems are among the biometric systems used in security and telephone-based remote control applications. Recent years have witnessed an increasing trend in research on such systems. These systems usually use high dimension feature vectors and therefore involve high complexity. However, there is a general belief that many of the features used in such systems are irrelevant and redundant. So far, many methods for feature dimension reduction in these systems have been proposed, most of which are wrapper-based and thus computationally expensive since system performance is used for feature subset evaluation. This involves system training and performance evaluation for each feature subset, which is a time consuming task. In this paper, we propose a feature selection approach based on Relieff algorithm for ASV systems using support vector machine (SVM) classifiers. This method is wrapper-based but makes use of Relieff weights in order to have a lower using of system performance. Thus this method has lower complexity compared to other wrapper-based methods, can lead to 69% feature dimension reduction and has a 1.25% of Equal Error Rate (EER) for the best case that appeared in RBF kernel of SVM. The proposed method has been compared with Genetic Algorithm (GA) and Ant Colony Optimization (ACO) methods for feature selection task. Results show that the EER, number of selected features and time complexity of the proposed method is lower than these methods for different kernels of SVM.

 
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