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Session 4: Life Science & Physical Science
In-silico analysis and screening of trehalose biosynthesis pathways in Antarctica lichenassociated Variovorax sp. PAMC28711
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- 발행기관
- 선문효정학술연구회 바로가기
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- 간행물
- 선문효정학술연구회 학술대회 프로시딩 바로가기
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- 통권
- Proceedings of THE 1st INTERNATIONAL CONFERENCE OF HYOJEONG ACADEMY 2023 (2023.01)바로가기
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- 페이지
- pp.62-66
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- 저자
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- 언어
- 영어(ENG)
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- URL
- https://www.earticle.net/Article/A488971
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4,000원
원문정보
초록
- 영어
- Trehalose is a naturally occurring disaccharide that is abundantly present in nature. Its presence in cells as several effects, especially because it acts as a natural defender of proteins and membranes. It utilized in food, cosmetics, and medications because of its excellent water retention properties. Following its esterification with fatty acids of different chain lengths, trehalose has also been shown to have anti-bacterial, anti-biofilm, and antiinflammatory properties. Trehalose plays a structural part in the bacterial cell wall’s adaptive reactions to stressors including osmotic variations high temperature. Additionally, it was proposed that when bacterial cells are exposed to harsh environment challenges such as heat, cold, desiccation, or reactive oxygen species, these organisms biosynthesize high concentrations of both intra- and extracellular trehalose to help them to survive. Therefore, we analyzed Variovorax sp. PAMC28711 isolate from Antarctica, which was predicted by bioinformatics tools (RAST, Prokka, KEGG, CGView Server, and MetaCyc) to predict the enzymes involved in the different pathways of trehalose production. Furthermore, TLC analysis was carried out to characterize various trehalose biosynthesis pathways. According to the findings, it revealed that our polar bacteria Variovorax sp. PAMC28711 have potential to produce trehalose through three (OtsA/B, TS, and TreY/Z) pathways. We anticipate that this strain could be of potential use for manufacturing trehalose in the industrial scale.
목차
Abstract
1. Introduction
2. Materials and Methods
2.1. Prediction of trehalose biosynthesis pathways in Variovorax sp. PAMC28711
2.2. Screening of trehalose biosynthesis pathways in Variovorax sp. PAMC28711
3. Results, Discussions, and Conclusions
4. Conclusions
Acknowledgement
References
저자
간행물 정보
발행기관
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- 발행기관명
- 선문효정학술연구회 [Sun Moon Hyojeong Academy Society]
- 설립연도
- 2023
- 분야
- 복합학>학제간연구
- 소개
- Journal of Hyojeong Academia aims to serve as a global platform where researchers and scholars of various disciplines can contribute ideas for our sustainable global community of Co‐existence, Co‐prosperity, and Co‐righteousness. The journal is a multidisciplinary, open‐access, internationally peer‐reviewed academic journal, and it invites all areas of research conducted in the spirit of post materialism including studies centering on God, studies unifying religions and sciences, and studies on all aspects of Co‐existence, Co‐prosperity, and Co‐righteousness.
간행물
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- 간행물명
- 선문효정학술연구회 학술대회 프로시딩
- 간기
- 반년간
- 수록기간
- 2023~2026
- 십진분류
- KDC 238 DDC 289
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