Earticle

초록

영어

In this study, Onyx has been successfully applied in the treatment of various neurovascular lesions. However, some experience is required to be accustomed to its unpredictable fluoroscopic visibility during injection. This in vitro study aimed to evaluate the characteristics of radiopacity change in simulated embolization procedure. Using a bench-top Onyx injection experiment simulating a typical brain arteriovenous malformation embolization, simplified into casting mode(continuous injection) and plugging mode(injection with intermittent pauses), nine cycles of casting and plugging mode were performed. Radiodensity of Onyx droplets collected from the distal end and the distal portion of the microcatheter was measured considering time lapsed. Distribution of droplet radiodensity and distrobution of radiographic grade in both modes were analysise and compared by repeated measures. Relationship between of droplet radiodensity and microcatheter radiographic grade[mean and standard deviation(SD)] was evaluated through correlation analysis. Within-group analysis revealed no significant droplet radiodensity change with time(P>0.05). The droplet radiodensities were significantly higher in the casting mode than in the plugging mode(P<0.01). The lateral radiographic of the microcatheter showed higher radiopacity(P<0.01) and better evenness(P<0.01) in the casting mode than in the plugging mode. A significant difference in microcatheter attenuation(both radiographic grade mean and SD; P<0.01) was noted between the two modes. Droplet radiodensity had a significant influence on the radiopacity and radiopacity evenness of the microcatheter. The radiopacity of the Onyx can vary significantly over time because of early precipitation of tantalum powder. Radiopacity decreased significantly during plugging modes, characterized by pauses between injections. More experiments are needed for better visualization of the liquid embolic material.

목차

Abstract
Ⅰ. 서론
1. 연구의 목적 및 필요성
Ⅱ. 실험 및 방법
1. In vitro bench-top 실험 setting
2. Onyx 준비, 주입 및 수집
3. 방사선 사진학적 분석
4. 데이터 분석 및 통계
Ⅲ. 결과
1. Onyx의 방사선 불투과성
2. 미세카테터의 영상학적 등급
3. 방사선 불투과성과 방사선 영상학적 사이의 관계
Ⅳ. 고찰
참고문헌

키워드

저자

• 조예은 [ Ye-eun Jo | 서울아산병원 영상의학과 ]
• Yuan Yuan Jiang [ 동국대학교 생명공학과 ]
• 우정민 [ Jung Min Woo | 서울아산병원 영상의학과 ]
• 임옥균 [ Ok Kyun Lim | 서울아산병원 영상의학과 ]
• 황창모 [ Changmo Hwang | 서울아산병원 영상의학과 ]
• 맹준영 [ Jun Young Maeng | 서울아산병원 영상의학과 ]
• 김지은 [ Jieun Kim | 서울아산병원 영상의학과 ]
• 김남국 [ Namkug Kim | 서울아산병원 영상의학과 ]
• 이덕희 [ Deok Hee Lee | 서울아산병원 영상의학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한디지털의료영상학회논문지 [Korean Journal of Digital Imaging in Medicine]

• 간기

  연3회

• pISSN

  1976-7641

• 수록기간

  1995~2025

• 십진분류

  KDC 510 DDC 610