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Correlation between content of major components and α-glucosidase inhibitory activity according to the cultivation stage of Hericium erinaceus

첫 페이지 보기
  • 발행기관
    한국버섯학회 바로가기
  • 간행물
    버섯 바로가기
  • 통권
    제27권 1호 통권 46호 (2023.06)바로가기
  • 페이지
    pp.41-41
  • 저자
    Se Hwan Ryu, Ayman Turk, Sang Won Yeon, Solip Lee, Beom Seok Kim, Sung Min Ko, Bang Yeon Hwang, Mi Kyeong Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A433478

원문정보

초록

영어
Hericium erinaceus (lion’s mane mushroom) is an edible and medicinal mushroom that belongs to the family Hericiaceae. It has been traditionally used for the treatment of memory impairment and gastrointestinal diseases. We previously reported hericene A as an anti-diabetic constituent of H. erinaceus and investigated the effect of cultivation substrates on its content. As the continuation, the contents of five major compounds, including hericenes A-D, which exhibit α-glucosidase inhibitory activity together with ergosterol, were investigated according to the cultivation stage. H. erinaceus was cultured for 5 stages to induce fruiting bodies, and the contents of the compounds at each stage were quantified through HPLC analysis. Among the major compounds the content of hericene A was the highest, followed by hericene C and the content of hericenes B and D was relatively low. The contents of four hericene derivatives are the highest at stage 4 whereas the content of ergosterol was highest at stage 5. The highest α-glucosidase inhibitory activity of H. erinaceus was at stage 4, which correlates with the contents of hericene derivatives. Conclusively, H. erinaceus with better efficacy and high content of active constituents can be secured by the optimization of cultivation conditions.

키워드

Hericium erinaceus cultivation perioid hericenes A-D ergosterol quantitation anti-diabetes

저자

  • Se Hwan Ryu [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]
  • Ayman Turk [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]
  • Sang Won Yeon [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]
  • Solip Lee [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]
  • Beom Seok Kim [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea, C&G Agricultural Association, Sejong 30067, Republic of Korea ]
  • Sung Min Ko [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea, C&G Agricultural Association, Sejong 30067, Republic of Korea ]
  • Bang Yeon Hwang [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]
  • Mi Kyeong Lee [ College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국버섯학회 [The Korean Society of Mushroom Science]
  • 설립연도
    1997
  • 분야
    농수해양>농학
  • 소개
    우리나라의 버섯 연구와 관련 산업의 발전에 기여하고 버섯관련 연구자와 관련산업 종사자간의 학술정보 등의 교류를 목적으로 한다.

간행물

  • 간행물명
    버섯 [Mushroom]
  • 간기
    반년간
  • 수록기간
    1997~2025
  • 십진분류
    KDC 525 DDC 635

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