Antioxidant and Elastase, Tyrosinase, α-Glucosidase Inhibitory Effects of Five Types of Mint Extracts
민트류 5종 추출물의 항산화 및 elastase, tyrosinase, α-glucosidase 저해효과
Purpose: This study evaluated the biological activity of five types of mints (Peppermint, Spearmint, Chocomint, Applemint, Pineapplemint). Methods: Five types of mints were extracted with an ethanol solvent to compare the total polyphenol and total flavonoid content, scavenging activities of DPPH and ABTS radical, SOD-like activity, and inhibitory effects of elastase, tyrosinase, and α-glucosidase. Results: All five types of mint extracts were confirmed to be effective significantly in concentration. The total polyphenol content was found to be effective in the order of peppermint>spearmint>chocomint>pineapplemint>applemint, and the total flavonoid content was found to be effective in the order of peppermint> chocomint>spearmint>pineapplemint>applemint. The DPPH radical scavenging activity was found to be in the order of peppermint>spearmint>chocomint> pineapplemint>applemint, and the ABTS radical scavenging activity was found to be in the order of peppermint>chocomint>spearmint>pineapplemint>applemi nt. The SOD-like activity was found to be in the order of peppermint>chocomint> spearmint> pineapplemint>applemint. The inhibitory effects of elastase, tyrosinase, α-glucosidase were found to be in the order of peppermint>spearmint>chocomint> pineapplemint>applemint. Conclusion: As above results, all five types of mint extracts were verified to be effective significantly in concentration. In particular, peppermint indicated the highest total polyphenol, total flavonoid, DDPH and ABTS radical scavenging activity, and SOD-like activity, while chocomint displayed the highest tyrosine, elastase, and α-glucosidase inhibitory effects.
한국어
목적: 본 연구는 대표적 허브식물로 알려져 있는 민트류의 생리활성을 평가하기 위해 5종(peppermint, spearmint, chocomint, applemint, pineapplemint)의 민트류를 비교하였다. 방법: 민트류 5종을 에탄올 용매로 추출하여 총 폴리페놀과 총 플라보노이드 함 량, DPPH 라디컬, ABTS 라디컬 소거능, SOD 유사활성능, elastase, tyrosinase, α-glucosidase 저해효과를 비교하였다. 결과: 민 트류 5종 추출물은 모두 농도 유의적으로 효과가 확인되었다. 특히 총 폴리페놀 함량은 peppermint>spearmint >chocomint>pineap plemint>applemint 순으로 확인되었으며, 총 플라보노이드는 peppermint>chocomint>spearmint>pineapplemint>applemint 순으로 확인되었다. DPPH 라디컬 소거능은 peppermint>spearmint >chocomint>pineapplemint>applemint 순이며, ABTS 소거능은 peppe rmint>chocomint>spearmint>pineapplemint>applemint 순으로 소거능이 확인 되었다. SOD 유사활성능은 peppermint>chocomint >spearmint>pineapplemint>applemint 순으로 확인되었다. Elastase, tyrosinase, α-gucosidase 저해효과는 peppermint>spearmint >chocomint>pineapplemint>applemint 순으로 저해효과가 확인 되었다. 결론: 이상의 결과 민트류 5 종 추출물은 모두 농도 유의적 으로 효과가 확인되었다. 특히 페퍼민트는 총 폴리페놀과 플라보노이드, DPPH, ABTS 라디컬 소거능, SOD 유사활성능이 높게 확 인 되었으며, 초코민트는 tyrosinase, elastase, α-glecosidase 저해효과가 가장 높게 확인 되었다.