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A Case Report of Reversal with Sugammadx in a Myasthenic Patient

첫 페이지 보기
  • 발행기관
    ASCONS 바로가기
  • 간행물
    IJBSA 바로가기
  • 통권
    Volume 2 Number 2 (2020.09)바로가기
  • 페이지
    pp.9-12
  • 저자
    Ju Han Mun, Cheol Jong Woo, Jeongwoo Lee, Dong-Chan Kim, Jun Ho Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A395190

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초록

영어
Background/Objectives: Myasthenia gravis (MG) is an autoimmune disease caused by the development of antibodies against the nicotinic acetylcholine receptor. Methods/Statistical analysis: MG causes weakness and fatigue of the respiratory muscles, so that there is hypersensitivity against non-depolarizing muscle relaxants. In general acetylcholinesterase inhibitors are administered to reverse the muscle blockade, but the use of neuromuscular blocking agents in myasthenic patients is usually delayed due to the drugs that already inhibit cholinesterase, resulting in a delay in spontaneous respiration. Sugammadex eliminates the effects of steroid non-depolarizing muscle relaxants, such as rocuronium and vecuronium, by selectively encapsulating their molecules. Case: We present a case of reversal of neuromuscular blocking agent and return to spontaneous respiration with sugammadex in a myasthenic patient. Findings: We also evaluated the degree of spontaneous respiration by comparing pulmonary function tests before and after surgery in a MG patient. Improvements/Applications: Sugammadex is a good option of fast reversal of neuromuscular blocking agent and return to spontaneous respiration in a myasthenic patient.

목차

Abstract
I. INTRODUCTION
II. CASE REPORT
Ⅲ. DISCUSSION
REFERENCES

키워드

Myasthenia gravis Sugammadex Nicotinic acetylcholine receptor Acetylcholinesterase inhibitors Cholinesterase Neuromuscular blocking

저자

  • Ju Han Mun [ Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and hospital, Jeonju, Korea ]
  • Cheol Jong Woo [ Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and hospital, Jeonju, Korea ]
  • Jeongwoo Lee [ Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and hospital, Jeonju, Korea ]
  • Dong-Chan Kim [ Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and hospital, Jeonju, Korea ]
  • Jun Ho Lee [ Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and hospital, Jeonju, Korea ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    ASCONS [The Academic Society of Convergence Science Inc]
  • 설립연도
    2017
  • 분야
    복합학>과학기술학

간행물

  • 간행물명
    IJBSA
  • 간기
    계간
  • pISSN
    2619-8363
  • 수록기간
    2019~2022
  • 십진분류
    KDC 327 DDC 332

이 권호 내 다른 논문 / IJBSA Volume 2 Number 2

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