Earticle

초록

영어

In Korea, the first patient with a left ventricular assist device (LVAD) for destination therapy had successful implantation of a continuous-flow model in 2012. We investigated the safety and efficacy of exercise ther-apy with LVAD implantation 15 Korean patients. We retrospectively re-viewed 15 patients (mean age, 67.4±11.6 years; 10 males, 5 female, left ventricular ejection fraction 23.6%±7.1%), including 4 with implanted continuous-flow and 11 an axial-flow LVAD. The New York Heart Asso-ciation functional classification, ejection fraction, and quality of life were obtained. Survival rate, adverse events, admission rates, and en-rollment rates in cardiac rehabilitation were investigated. Survival at 6 and 12 months was 100% and 89%, respectively. The New York Heart Association functional classification improved from 3.4±0.5 to 2.3±0.05 at 12 months postoperatively (P<0.0001). The ejection fraction signifi-cantly increased from 23.6%±7.2% on the preoperative day to 35.4%±14.2% at 1 year (P<0.0018). The quality of life was also improved at 1 year (P<0.0001). The most common adverse events were bleeding (56%) and dyspnea (44%). The number of admissions was 3.2 per pa-tient-year. LVAD therapy is a safe and effective treatment option with exercise intervention for Korean patients waiting for heart transplanta-tion or those who were ineligible for heart transplantation. A larger study with longer follow-up is needed to determine details clinical out-comes after LVAD.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Patient selection
Exercise-based cardiac rehabilitation
Follow-up
Statistical analysis
RESULTS
Baseline patient characteristics
Adverse events
Cardiac rehabilitation participation rate
Readmission
Clinical outcomes
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES

키워드

저자

• Yong Gon Seo [ Division of Sports Medicine, Department of Orthopedic Surgery, Samsung Medical Center, Seoul, Korea ]
• Won Hah Park [ Division of Sports Medicine, Department of Orthopedic Surgery, Samsung Medical Center, Seoul, Korea ]
• SuKi Oh [ Division of Sports Medicine, Department of Orthopedic Surgery, Samsung Medical Center, Seoul, Korea ]
• Jidong Sung [ Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea ]
• Eun Seok Jeon [ Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea ]
• Jin Oh Choi [ Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea ]
• Jae K. Oh [ Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea ]
• Yun Hee Kim [ Cardiac Rehabilitation and Prevention Center, Samsung Medical Center, Seoul, Korea ]
• Ho Young Kim [ Cardiac Rehabilitation and Prevention Center, Samsung Medical Center, Seoul, Korea ]
• Mi Ja Jang [ Department of Nursing, Cardiac Rehabilitation and Prevention Center, Samsung Medical Center, Seoul, Korea ]
• Nam Gyung Choi [ Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Seoul, Korea ]
• Yang Hyun Cho [ Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Seoul, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613