Earticle

초록

영어

Fogo Selvagem (FS) is a rare autoimmune disease characterized by ac-antholysis and inflammation of the epidermis. It was evidenced in this disease the increase of pro-inflammatory cytokines levels which can be influenced by physical activities. Kinesiotherapy, as physiotherapeu-tic interventions, was associated improvement levels of the quality of live, mainly the pain. Understanding the impact of such methodology in immunology of the FS, may constitute an alternative and effective ap-proach. We compare the levels of serum cytokines and chemokines between nine patients with FS submitted to kinesiotherapy for 12 weeks and ten patients not submitted to kinesiotherapy. The kinesiotherapy was composed by self-stretching followed by a resistance training for upper and lower limbs. The protocol was carried out in three sections of eight to ten repetitions with 70% of the maximum load measured by test maximum of ten repetitions. After strengthening period patients performed a passive stretching. The training sessions lasted 50 min and were performed 3 times a week at least 12 weeks. Cytokines and chemokines were assessed in plasma using enzyme-linked immuno-sorbent assay and/or cytometric bead array. Patients with FS were be-ing kinesiotherapy presented minors levels of interferon-γ, interleukin (IL)-17, IL-22, and IL-15 when compared to those not submitted to kine-siotherapy. No differences were observed for the detection of the chemokines chemokine ligand (CCL)-2, CCL-3, CCL-5, CCL-11, C-X-C motif chemokine 8 (CXCL-8), and CXCL-10. These results suggest that kinesiotherapy had a positive impact on inflammatory markers that are associated with disease worsening in FS.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Study design
Participants
Chemokine and cytokine production
Kinesiotherapy protocol
Data analysis and statistics
RESULTS
Participants
Kinesiotherapy modulates key cytokines in serum of patients with the endemic form of PF
Kinesiotherapy seems not to be effective in the modulation of chemokines in FS
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
SUPPLEMENTARY MATERIAL
REFERENCES

키워드

저자

• Rodolfo Pessato Timóteo [ Federal University of Triângulo Mineiro, Uberaba, Brazil ] Corresponding Author
• Helioswilton Sales-Campos [ Federal University of Goiás, Goiânia, Brazil ]
• Marcos Vinicius Silva [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Djalma Alexandre Alves da Silva [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Jonatas Da Silva Catarino [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Marlos Aureliano Dias de Sousa [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Virmondes Rodrigues Júnior [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Leonardo Eurípedes de Andrade e Silva [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Ana Carolina Silva Bittencourt [ Physiotherapy Division (EBSERH/UFTM). Clinical Hospital of Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Élida Mara Carneiro [ Physiotherapy Division (EBSERH/UFTM). Clinical Hospital of Federal University of Triângulo Mineiro, Uberaba, Brazil ]
• Carlo José Freire Oliveira [ Federal University of Triângulo Mineiro, Uberaba, Brazil ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613