Melek Tunc-Ata, Mukaddes Mergen-Dalyanoglu, Sebahat Turgut, Günfer Turgut
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영어(ENG)
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https://www.earticle.net/Article/A315369
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초록
영어
The relationship between acute and chronic exercise and expression of matrix metalloproteinases (MMPs) in muscles is unknown. There happen some alterations in the oxidant-antioxidant balance due to ex-ercise. This study aimed to investigate the levels of MMP-1, tissue in-hibitors of metalloproteinases (TIMP-1), hyaluronic acid (HA), total anti-oxidant status (TAS), and total oxidant status (TOS) following acute and chronic exercising in rats. Twenty-six Wistar Albino male rats were di-vided in to three groups: control, acute, and chronic groups. In acute group, treadmill exercise was performed 3 days/wk, 10 min/day for 1 week. In chronic group, exercise performed 7 days/wk, 60 min/day for 4 weeks. At the end of the experiment, plasma MMP-1, TIMP-1, HA, TAS, and TOS levels were measured. In current study, the MMP-1, TIMP-1, HA, and TOS levels not observed statistically significant difference among all groups, but in chronic group, there was a significantly differ-ence (P<0.05) between the control and experimental groups in terms of TAS and oxidative stress index (OSI) levels. TAS, TOS, and OSI levels were significantly different between control and chronic exercise group (P<0.01, P<0.05, and P<0.01, respectively). According to these results, we can say acute and chronic exercise does not effect on plasma MMP-1, TIMP-1, and HA levels.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Animals and experimental conditions Experimental design Blood samples and measurements Statistical analysis RESULTS DISCUSSION CONFLICT OF INTEREST REFERENCES
키워드
AcuteChronicExerciseMatrix metalloproteinase
저자
Melek Tunc-Ata [ Department of Physiology, Pamukkale University Medical Faculty, Denizli, Turkey ]
Corresponding author
Mukaddes Mergen-Dalyanoglu [ Department of Physiology, Pamukkale University Medical Faculty, Denizli, Turkey ]
Sebahat Turgut [ Department of Physiology, Pamukkale University Medical Faculty, Denizli, Turkey ]
Günfer Turgut [ Department of Physiology, Pamukkale University Medical Faculty, Denizli, Turkey ]