Earticle

초록

영어

The present study aimed to compare the effects of moderate-intensity continuous and high-intensity interval exercise training (ET) on exercise tolerance, cardiac morphometry and function, hemodynamic, and car-diac autonomic modulation in myocardial infarcted mice. Wild-type mice (WT) were divided into four groups: sedentary WT (S); WT myo-cardium infarction sedentary (IS); WT myocardium infarction under-went to moderate-intensity continuous ET (MICT), and WT myocardium infarction underwent to high-intensity interval ET (MIIT). After 60 days of descending coronary artery ligation, moderate-intensity continuous ET consisted of running at 60% of maximum, while the high-intensity in-terval training consisted of eight sprints of 4 min at 80% of maximum and a 4-min recovery at 40% of maximum. Both exercises were per-formed 1 hr a day, 5 days a week, during 8 weeks. Results demonstrated that IS showed elevated exercise tolerance, as well as decreased he-modynamic and heart function, and autonomic control. On the other hand, both programs of ET were equally effective to increase all param-eters, without further differences between the groups. In conclusion, the results of the present study showed that myocardial infarction leads to damage in both investigated strains and the two types of physical ex-ercise attenuated the major impairments provoked by myocardial in-farction in exercise tolerance, cardiac structure, cardiac function, he-modynamic and cardiac autonomic modulation.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Animals
  Infarct surgery
  Left ventricular function
  Groups
  Maximal exercise test and training protocols
  Hemodynamics
  Autonomic function
  Statistical analysis
 RESULTS
  Exercise tolerance
  Echocardiographic measurements
  Hemodynamic evaluation
  Autonomic function
 DISCUSSION
 CONFLICT OF INTEREST
 ACKNOWLEDGMENTS
 REFERENCES

키워드

저자

• Cesar Cavinato Cal Abad [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ] Corresponding author
• Ademir Manuel do Nascimento [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Leandro Eziquiel dos Santos [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Diego Figueroa [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Pamella Ramona [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Michele Sartori [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Katia B. Scapini [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Oscar Albuquerque [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Ivana Cinthya Moraes-Silva [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]
• Hélio José Coelho-Júnior [ Faculty of Physical Education, University of Campinas (UNICAMP), Campinas, Brazil ]
• Bruno Rodrigues [ Faculty of Physical Education, University of Campinas (UNICAMP), Campinas, Brazil ]
• Cristiano Teixeira Mostarda [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil, Federal University of Maranhão (UFMA), São Luiz, Brazil ]
• Kátia De Angelis [ Translational Physiology Laboratory, Nove de Julho University (UNINOVE), São Paulo, Brazil ]
• Maria Cláudia Irigoyen [ Hypertension Unit, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613