Earticle

초록

영어

The anti-hyperglycemic effect of methanolic soluble fractions of Cressa cretica (Convolvulaceae) made up of the whole plant (flower, root, leaf, stem) was investigated in alloxan (150 mg/kg) induced hyperglycemic Wistar rats. It’s effect was compared with that of negative control, glibenclamide (0.9 mg/kg) as standard reference drug and Vit-E (100 IU/kg) as anti-oxidant standard. The physico-metabolic parameters measured were: Body weight, glycogen content in liver and muscle, serum glucose, speroxide desmutase (SOD) and histopathological examination of pancreas were also observed. Oral administration of MECC (200 mg/kg, 400 mg/kg) for 28 days exhibited a significant reduction in blood glucose. An improvement of glycogen content in liver and muscle, body weight, hepatic enzyme like SOD was observed. The results of this work suggest that MECC may possess anti-hyperglycemic and anti-oxidant property.

목차

Abstract
 Introduction
 Material and Methods:
  Collection and Identification of Plant Material
  Preparation of Plant Extract
 Experimental Animals
  Acute Toxicity Study
  Induction of Diabetes
  Experimental Study Design:
  Statistical Analysis
 Results and Discussion
  Plant Extraction
  Preliminary Phytochemical Screening
  Acute Toxicity Study
  Anti-Diabetic Study
  Effect of Various Treatments on Glycogen Content in Liver and Muscle
 Conclusion
 References

키워드

저자

• Lalitha Kumari, B. [ Asst. Prof., Dept.of S&H, VFSTRU, Vadlamudi, Guntur (Dt.), A.P. India ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  International Journal of Bio-Science and Bio-Technology

• 간기

  격월간

• pISSN

  2233-7849

• 수록기간

  2009~2016

• 등재여부

  SCOPUS

• 십진분류

  KDC 505 DDC 605