Earticle

초록

영어

Pulmonary arterial hypertension (PAH) is a rare and devastating dis-ease which is characterized by worsening dyspnea and exercise toler-ance. These patients are often found to have concomitant, depression, anxiety and impaired health-related quality of life (HRQOL). The interre-lationship of dyspnea, depression and HRQOL in these patients is not well studied. Retrospective analysis was performed on 46 PAH patients (mean age 51.73). Patients completed Medical Outcomes Study Short - Form 36 V2 (SF-36) to measure HRQOL, Modified Medical Research Council (mMRC) Dyspnea Scale and Zung Depression Scale (ZDS). Physical Health Composite Scores (PCS) and Mental Health Composite Scores (MCS) were derived from SF-36. Spearman’s correlation was computed to determine degree of correlation between pairs of scales. 46 patients (12 males, 34 females; median age 51.4 yr) with confirmed PAH were considered for the study of which 36 patients (9 males, 27 fe-males, median age 50.1 yr), were eligible for further analysis. MMRC Dyspnea Scale Score was 1.0 (Q1 to Q3:1.0 to 2.0). Median MCS was 52.1 (Q1 to Q3:41.7 to 57.1) and PCS was 37.9 (Q1 to Q3: 30.7 to 49.6). There was a significant negative correlation between dyspnea and PCS (r =-0.660, P<0.0001) and MCS (r =-0.342, P<0.0411). The ZDS was avail-able for 17 of these patients; their median score was 42.0 (Q1 to Q3: 33.0 to 46.0). There was a significant correlation between the ZDS and PCS (r =-0.578, P<0.0150,) MCS (r =-0.752, P<0.0005). Patients with PAH suffer from diminished HRQOL correlating with their dyspnea and underlying depression.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Patients
  Measuring dyspnea, depression and health related quality of life
  Dyspnea
  Depression
  Health related quality of life (HRQOL)
 RESULTS
 DISCUSSION
 REFERENCES

키워드

저자

• Arunabh Talwar [ North Shore-Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, New Hyde Park, NY, USA, Feinstein Institute for Medical Research, Manhasset, NY, USA ] Corresponding author
• Sonu Sahni [ North Shore-Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, New Hyde Park, NY, USA, Feinstein Institute for Medical Research, Manhasset, NY, USA ]
• Eun Ji Kim [ North Shore-Long Island Jewish Health System, Department of Medicine, Manhasset, NY, USA ]
• Sameer Verma [ North Shore-Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, New Hyde Park, NY, USA, Feinstein Institute for Medical Research, Manhasset, NY, USA ]
• Nina Kohn [ Feinstein Institute for Medical Research, Manhasset, NY, USA ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613