Earticle

초록

영어

This study was designed to examine effects of Korean Acer tegmentosum Maximowocz extract, which has traditionally been used for the treatment of liver damages in fat diet-induced obese rats. 40 male SD rats were divided into three groups: normal diet (Control group, n=10), 40% fat diet-induced obese rats (Obesity group, n=15), and Acer tegmentosum Maximowoczextract diet with 40% fat diet-induced obese rats (ATM group, n=15). Hematological and biochemical variables were measured. Histological examinations of liver and adipose tissues were performed with hematoxylin & eosin stain. Total leukocyte, neutrophil, neutrophil/lymphocyte ratio, erythrocyte, platelet, hemoglobin, and red distribution width levels were significantly higher, whereas monocyte levels were lower in obesity group than in control and ATM group. Glucose, total cholesterol, triglyceride, LDL-cholesterol, AST, ALT, and BUN levels in obesity group were significantly greater than those of ATM. ATM group showed significantly lower liver fatty degeneration (steatosis) than obesity group. ATM group exhibited regular morphology of adipocytes and adipocyte sizes are smaller than obesity group, whereas obesity group showed larger and irregular shapes of adipocytes than ATM and control groups. These results suggest that Korean Acer tegmentosum Maximowocz exerts anti-inflammatory and anti-obesity effects.

목차

Abstract
 1. Introduction
 2. Materials and Methods
 3. Results
 4. Discussion
 Appendix
 Acknowledgments
 References

키워드

저자

• Jeong-Won Kim [ Depart. of Clinical Laboratory Science, Catholic University of Pusan, Busan 609-757, Korea ]
• Kyung-Soo Chang [ Depart. of Clinical Laboratory Science, Catholic University of Pusan, Busan 609-757, Korea ]
• Yun-Tae Kim [ Depart. of Molecular Biology, Seoul Medical Science Institute/Seoul Clinical Laboratories, Yongin 446-908, Korea, ]
• Kyung-Yae Hyun [ Depart. of Clinical Laboratory Science, Dong-Eui University, Busan 614-714, Korea ]
• Joon-Sun Lee [ Depart. of Clinical Laboratory Science, Dong-Eui University, Busan 614-714, Korea ]
• Mi-Ha Joo [ Depart. of Clinical Laboratory Science, Dong-Eui University, Busan 614-714, Korea ]
• Hwa-Sik Choi [ Depart. of Clinical Laboratory Science, Shinhan University, Uijungbu, 480-701, Korea ]
• Seok-Cheol Choi [ Depart. of Clinical Laboratory Science, Catholic University of Pusan, Busan 609-757, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  International Journal of Bio-Science and Bio-Technology

• 간기

  격월간

• pISSN

  2233-7849

• 수록기간

  2009~2016

• 등재여부

  SCOPUS

• 십진분류

  KDC 505 DDC 605