Earticle

초록

영어

By using the Rumex crispus L. leaf ethanol extract, the attempt is undertaken to measure the melanin inhibitory activity and tyrosinase inhibitory activity and cell viability in B16F10 melanoma cells, melanin inhibitory activity and the essence and pack manufactured by applying to the melanin and erythema values were also studied in a way of reviewing the function as the functional cosmetics composition. As a result, the inhibition of the tyrosinase was shown its effect at the density of 125 ug/mL of extracted material. For the B16F10 cell, the cell viability show the higher than 90% survived in concentration under 100ug/mL. The tyrosinase activation control was shown to be 8.0% at 100 ug/mL while the melanin inhibitory activity was for 13.0%. The change of the melanin and erythema value of skin was shown to have the noticeable difference (p<.001) in the experiment group following the time of use for the index prior to experiment compared to the contrast group. According to this result, the Rumex crispus L. leaf extract had affected for the skin to brighten and showed possibility material of functional cosmetics. It looks like there needs to be continuing research about this matter.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 재료 및 시료의 추출
  2. 사용 시약 및 기기
  3. 세포배양
  4. 세포 생존율 측정
  5. Tyrosinase 활성 저해
  6. B16F10 세포에서 tyrosinase 활성 저해
  7. B16F10 세포에서 melanin 형성 억제 효과
  8. 소리쟁이 잎 추출물을 함유한 로션과 팩의 제조
  9. 피부상태 측정
  10. 통계처리
 Ⅲ. 연구결과 및 고찰
  1. RCL에 의한 Tyrosinase 활성 저해
  2. RCL에 의한 B16F10 세포 생존율
  3. RCL에 의한 B16F10 세포에서의 tyrosinase 활성 저해
  4. RCL에 의한 B16F10 세포에서의 멜라닌 형성 억제 효과
  5. 연구대상자의 동질성 검증과 안전성 평가
  6. 피부표면의 멜라닌지수 변화
  7. 피부표면의 홍반지수 변화
 Ⅳ. 결론
 참고문헌

키워드

저자

• 박주아 [ Ju-A Park | 동부산대학교 뷰티피부미용과 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646