Earticle

초록

영어

Recently, Korea’s domestic cosmetics market is as large as over KRW 6 trillion, the export of cosmetic products has reached US 600 million dollars. Even though anti-aging cosmetics market has grown to more than KRW 300 billion industry, the supply of cosmetic materials has been hugely dependent on import (80%). As consumers seek more nature-friendly and organic products, world’s natural and organic cosmetics market has reached a value of approximately KRW 10 trillion. Under these circumstances, it is urgent to develop raw materials for natural cosmetics. Therefore, this study attempted to investigate aronia which has lately drawn a great attention. Aronia is a berry plant in the family Rosaceae, which grows in the northeastern part of North America. It was first introduced to the Republic of Korea in 2007. The Russian botanist Ivan Michurin started to reveal the diverse values of the shrub. It’s been known that the perennial plant has abundant anthocyanin in its flesh and skin. According to comparison between aronia and berries, the deciduous shrub is 4 times higher than blueberry in terms of anthocyanin contents. In other words, it is the best natural substance in getting anthocyanin among existing berries. Recently, there have been a lot of studies on aronia in food industry. In cosmetic industry, however, it’s still very new. Therefore, this study examined if the native American fruit would be available as a cosmetic material. In an NR assay on the aronia extract in RAW264.7, HDF and B16F10, 80% or higher cell survival rates were confirmed in all concentrations. According to an NO assay on RAW264.7, for example, NO production was cut to less than 80%. With α-MSH treatment on B16F10, melanin, the production of melanin was induced. With the addition of aronia extract in different concentration levels, melanin synthesis-inhibiting effects occurred in a concentration-dependent manner, which inhibits tyrosinase expression. Therefore, it appears that it would be available as a material for whitening cosmetics. When UV rays were applied to HDF, MMP-1 expression declined more than 50% until the aronia extract reach up to 50 ㎍/mL. In other words, the inhibition of MMP-1 expression was confirmed after ERK and JNK activities were slowed down. In sum, this study confirmed the efficacy of aronia as a natural cosmetic material by proving the effects of inhibiting NO, melanin synthesis and MMP-1 production. It is likely that this natural substance would be available as a cosmetic material and academic data in cosmetics and skin beauty sectors.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 재료 및 방법
  1. 실험재료
  2. 시약 및 기기
  3. 세포배양
  4. 사용기기
  5. Neutral Red assay를 이용한 세포독성 측정
  6. Nitric oxide 생성능 측정
  7. Melanin 생성 저해능 측정
  8. MMP-1 발현 억제능 측정
  9. Western blot
 Ⅲ. 연구결과
  1. 아로니아 추출물의 항염증 효과
  2. 아로니아 추출물의 항멜라닌 효과
  3. 아로니아 추출물의 항노화 효과
 Ⅳ. 결론
 참고문헌

키워드

저자

• 신동화 [ Donghwa Shin | 건국대학교 일반대학원 생물공학과 ]
• 최태부 [ Taeboo Choe | 건국대학교 생물공학과 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646