Earticle

초록

영어

The formidable barrier property of the stratum cornemum and the high hydrophilicity of active ingredientmake it difficult to permeate through the skin and reach to its site of action. So the interest of cosmeticindustry is how to promote percutaneous absorption of active ingredients. The aim of this study wasto analysis and organize theses on percutaneous absorption of active ingredient. Physical penetrationenhancers on the skin permeation is iontophoresis, electroporation, sonophoresis, tape stripping, and soon. A physical penetration enhancer that has received greater attention lately is MTS (Microneedle TherapySystem). This therapy uses micro-needle which is equipped with very thin, delicate needles smaller than a0.07 mm thick hair. During this therapy, the micro-needle makes small holes and helps absorb the solutioninto the skin. But the penetration enhancers on the skin permeation that has received the greatest attentionsince 2005 is a hoof shape method, such as pH-responsive P (MAA-co-PEGMA) hydrogel, micelle, nanoemulsion, liposome, ethosome. Especially, theses on nano emulsion and liposome (including ethosome)hold a large majority. According to the theses, the ethosome exhibited more enhanced skin permeabilitythan general liposome and ethanol solution.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 본론
  1. 경피흡수 원리 및 경로
  2. 경피 흡수 촉진에 영향을 주는 일반적인 요인들
  3. 물리적 접근법
  4. 제형적 접근법
 Ⅲ. 결론
 참고문헌

키워드

저자

• 정지연 [ Ji-Yeon Chung | 원광보건대학교 미용피부관리과 ]
• 한효선 [ Hyo-Sun Han | 원광보건대학교 미용피부관리과, 고려전문학교 미용예술학과 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646