Earticle

초록

영어

This study was conducted to reveal medicinal effect of Berchemia berchemiaefolia (BB) extract for induced IBS-rat model. IBS was induced by injecting acetic acid into target of Spraque-Dawley rats' colon. Control group and experimental group were categorized as follows; Group I: control group (n=5), Group II: induced IBS (n=5), Group III: induced IBS+BB LD3 extract oral administration (n=5), Group Ⅳ: induced IBS+BB LD10 extract oral administration (n=5). The measurement of AWR was performed to determine the presence of disease leading and its alleviation. Also, we analyzed hematological factors, liver functional test, inflammatory factors, stress related factors, western blot and investigated significant differences in the variables among four groups. This research result shows that feeding orally BB extract to induced IBS rat alleviates violent contraction of colon of those rats.

목차

Abstract
 1. Introduction
 2. Materials and Methods
 3. Discussion
 4. Conclusion
 Acknowledgements
 References

키워드

Irritable Bowel Syndrome Berchemia berchemiaefolia AWR CRD nrf2 iNOS p38 cortisol serotonin IL-1β IL-6 TNF-α

저자

• Gilhyun Lee [ Depart. of Clinical Laboratory Science, Dong-Eui University, Pusan 614-714, Korea ]
• Junseon Lee [ Depart. of Clinical Laboratory Science, Dong-Eui University, Pusan 614-714, Korea ]
• Miha Joo [ Depart. of Clinical Laboratory Science, Dong-Eui University, Pusan 614-714, Korea ]
• Seokcheol Choi [ Depart. of Clinical Laboratory Science, Catholic University of Pusan ]
• Kyungyae Hyun [ Depart. of Clinical Laboratory Science, Dong-Eui University, Pusan 614-714, Korea ] Corresponding Author

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