Earticle

초록

영어

In this study we investigated antimicrobial and antioxidant activities of A. hookeri root extract and its fractions. Ethanol extract and n-hexane (HE) and methylene chloride (MC) fractions showed antimicrobial effect against microbes causing skin troubles such as pimple, atopic dermatitis and dandruff. Minimum inhibitory concentration (MIC) of HE fraction against Propionibacterium acnes (P. acnes), Malassezia furfur (M. furfur), and Staphylococcus aureus (S. aureus) were 2.5 mg/mL, 0.6 mg/mL and 0.2 mg/mL respectively. MIC of MC fraction against P. acnes, S. aureus and M. furfur were 3.0 mg/mL, 0.7 mg/mL and 0.3 mg/mL respectively. In addition, they showed antioxidant effect in DPPH assay. The half maximum scavenging concentrations (SC50) of ethanol extract and MC and EA fraction were 4.5 mg/mL, 0.1 mg/mL and 0.15 mg/mL respectively. These results suggest that A. hookeri root extract and its fractions be a new functional cosmetic ingredient with antioxidant and antimicrobial activity.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 기기 및 시약
  2. 삼채 뿌리 추출물 및 분획물 제조
  3. 사용 균주 및 배양조건
  4. 디스크 확산법(Disk diffusion method)
  5. 최소 억제 농도(Minimum inhibitory concentration: MIC)
  6. 항산화 활성
 Ⅲ. 연구결과 및 고찰
  1. 삼채 뿌리 추출물 및 분획물 제조
  2. 삼채 뿌리 추출물 및 분획물의 항균효과
  3. 삼채 뿌리 추출물 및 분획물의 항산화 효과
 Ⅳ. 결론
 감사의 글
 참고문헌

키워드

저자

• 이지영 [ Ji-Young Lee | (주)코리아나화장품 송파기술연구소 ] Corresponding author
• 이건국 [ Kun-Kook Lee | (주)코리아나화장품 송파기술연구소 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646