Earticle

초록

영어

The bioactive characteristics of curcumin, the main ingredient of Curcuma longa and Curcuma longa extract was studied to use as a cosmetic ingredient. The bioactive characteristics of cosmetic ingredients of this study include anti-microbial activity, anti-oxidation activity, anti-inflammation activity, whitening effect. The anti-oxidation activity has found that curcumin has the radical scavenging ability and polyphenol with high anti-oxidative activity. The anti-bacterial effect of curcumin and Curcuma longa extract has found to show the comparatively lower anti-bacterial effect in the 5 strains including S.aureus, E.coli, P.aeruginosa, C.albicans, and M. furfur. The anti-inflammatory effect of curcumin has found that the inhibition concentration, IC50 of NO production was as low as 6 μM. The anti-melanin effect of curcumin has found that about 60% of melanogenesis was inhibited at 20 μM of curcumin concentration by using B16F10 cell when compared to that of the control group. In conclusion, Curcuma longa extract cannot be use as a cosmetic material, curcumin can be used as the functional cosmetics material in the future as it has found to have the weak anti-oxidant and anti-bacterial effects and strong anti- inflammatory and anti-melanin effects.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 실험재료 및 세포배양
  2. 항산화 활성 측정
  3. 항균 활성 측정
  4. Neutral Red assay를 이용한 세포 독성 검사
  5. Nitric oxide 생성능 측정
  6. Melanin 생성 저해능 측정
 Ⅲ. 연구결과 및 고찰
  1. 강황 추출물과 커큐민의 항산화 활성
  2. 강황 추출물과 커큐민의 항균 효과
  3. 커큐민의 RAW 264.7과 B16F10 melanoma에 대한 세포독성
  4. 강황 추출물과 커큐민의 RAW264.7 세포에 대한 NO 생성능 억제
  5. 커큐민의 B16F10 melanoma 세포에 대한 멜라닌 저해능
 Ⅳ. 결론
 참고문헌

키워드

저자

• 정은진 [ Eun-Jin Jung | 선문대학교 교양학부 ]
• 최태부 [ Tae-Boo Choe | 건국대학교 생물공학과 ] Corrrsponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646