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Chemical constituents of Cordyceps militaris and their anti-aging activities in vascular endothelial cell

첫 페이지 보기
  • 발행기관
    한국버섯학회 바로가기
  • 간행물
    버섯 바로가기
  • 통권
    제17권 1호 통권 27호 (2013.05)바로가기
  • 페이지
    pp.88-89
  • 저자
    Hyung-Jun Noh, Geum-Sook Kim, Seung-Eun Lee, Gi-Ho Sung, Dae-Young Lee, Je-Hun Choi, Seung-Yu Kim, Jae-Ryong Kim
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A213789

원문정보

초록

영어
Cordyceps militar is (Clavicipitales) is an edible mushroom which is widely distributed in China, Japan and Korea. Various phytochemical constituents, cordycepin, homocitrully laminoadenosine and sterols have been reported from this source and a wide range of biological activities, including antimicrobial, macrophage activation, anticancer, immune modulatory effects were studied. In a continuing search for bioactive constituents from Korean mushrooms, we performed a phytochemical investigation of the MeOH extract from the fruiting bodies of C. militaris. By repeated column chromatographic separation of the extract, fourteen compounds, were isolated. The identification and structural elucidation of the compound was based on NMR spectral data. anti-aging activities were performed on adriamycin-induced cellular senescence model. Human dermal fibroblasts(HDFs) and human umbilical endothelial cells(HUVECs) treated with adriamycin for inducing aging were used for cytotoxicity and senescence-associated beta-galactosidase(SA-β-gal) activity assay.

저자

  • Hyung-Jun Noh [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Geum-Sook Kim [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Seung-Eun Lee [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Gi-Ho Sung [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Dae-Young Lee [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Je-Hun Choi [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Seung-Yu Kim [ Department of Herbal Crop Research, NIHHS, RDA, Eumsung, 369-873, Korea ]
  • Jae-Ryong Kim [ College of medicine, Yeungnam University, Daegu 705-717, Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국버섯학회 [The Korean Society of Mushroom Science]
  • 설립연도
    1997
  • 분야
    농수해양>농학
  • 소개
    우리나라의 버섯 연구와 관련 산업의 발전에 기여하고 버섯관련 연구자와 관련산업 종사자간의 학술정보 등의 교류를 목적으로 한다.

간행물

  • 간행물명
    버섯 [Mushroom]
  • 간기
    반년간
  • 수록기간
    1997~2025
  • 십진분류
    KDC 525 DDC 635

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