Korean ginseng (Panax ginseng C.A. Meyer) is one of the most widely used medicinal herbs in the world. Although multiple biological activities of Korean ginseng have been widely studied, anti-oxidant property and moisturizing effect of oil exracted from Korean red ginseng (KRO) remains unknown. Here in vitro anti- oxidant activity and the moisturizing effect in 20-30 aged female of KRO were investigated. The peroxyl radicals are dose-dependently and significantly scavenged by KRO between 0.01-0.1% as judged by ORAC and its electron donating capacity was examined through reduction potential using copper ions. The KRO showed dose-dependent increasing reduction capacity between 0.01% and 0.1%. In addition, the KRO effectively attenuated AAPH- or Cu2+- induced oxidative stress in HepG2 cells. We further investigated the moisturizing effect of KRO in 20-30 aged female for 2 weeks. The treatment of moisturizer with KRO improved moisture content of skin in 20-30 aged female (n=4). These results imply that the KRO may be utilized as strategy for skin. In addition, our findings provide the scientific evidences for the development of skin targeted nutricosmetics and cosmetics.
목차
Abstract Ⅰ. 서론 Ⅱ. 연구방법 1. 실험 재료 2. 홍삼오일의 제조 3. 홍삼오일의 peroxyl radical 소거활성 4. Reduction capacity 5. HepG2 세포에서 홍삼오일의 항산화 활성 6. 시험제품의 제조 7. 피험자 선정 및 기준 8. 이상반응 평가 9. 홍삼오일의 보습활성 10. 통계분석 Ⅲ. 연구결과 및 고찰 1. 홍삼오일의 항산화 활성 2. HepG2 세포에서 홍삼오일의 산화적 스트레스 억제활성 3. 홍삼오일의 보습활성 Ⅳ. 결론 참고문헌
키워드
Red ginseng oilAnti-oxidantMoistureOxygen radical absorbance capacity
저자
손명수 [ Myung-Soo Shon | 경남대학교 식품생명학과 ]
송지혜 [ Ji-Hye Song | 한남대학교 식품영양학과 ]
김종식 [ Jong Sik Kim | (주)한국인삼공사 ]
장해동 [ Hae-Dong Jang | 한남대학교 식품영양학과 ]
김교남 [ Gyo-Nam Kim | 경남대학교 식품생명학과 ]
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