Earticle

초록

영어

This study investigated tyrosinase inhibitory and melanin production inhibitory activity of methanol extract and fractions from Dendropanax morbifera Lev. to examine its activation for skin whitening and discovered that ethyl acetate and n-butanol fractions had high capacity of tyrosinase inhibitory. Also, as a result of measuring melanin production inhibitory in B16F10 cells which were stimulated by α-MSH, it was discovered that ethyl acetate fractions within the range of concentration without cytotoxicity had higher repression effects. As ethyl acetate fractions had higher flavonoid contents and DPPH radical absorption capacity than those of other specimens and the ethyl acetate fractions in methanol extracts from Dendropanax morbifera Lev. had excellence in anti-oxidation, tyrosinase inhibitory, and melanin production inhibitory activity, this study suggested that they have potential as a functional material of skin whitening cosmetics.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 실험재료
  2. 추출 및 분획
  3. 세포주 배양
  4. 총 flavonoid 함량 측정
  5. MTT assay에 의한 세포독성 측정
  6. DPPH radical 소거능 측정
  7. Tyrosinase 저해 활성 측정
  8. Melanin 생성 억제 활성 측정
 Ⅲ. 연구결과 및 고찰
  1. 총 flavonoid 함량
  2. MTT assay에 의한 세포독성
  3. DPPH radical 소거능
  4. Tyrosinase 저해 활성
  5. Melanin 생성 억제 활성
 Ⅳ. 결론
 참고문헌

키워드

저자

• 모정희 [ Jeong-Hee Mo | 동신대학교 뷰티미용학과 ]
• 오수정 [ Su-Jeong Oh | 조선이공대학교 뷰티아트과 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한피부미용학회지 [Korean Journal of Aesthetics and Cosmetology]

• 간기

  격월간

• pISSN

  1738-4567

• 수록기간

  2003~2015

• 십진분류

  KDC 593 DDC 646