Herbal medicines have been used since the dawn of civilization to maintain health and to treat diseases. Diabetes mellitus is one of the leading cause of death in many developed countries. The incidence of diabetes is increasing at an alarming rate in India. It was estimated that India which had 19.4 million diabetes in 1995 is expected to register a near threefold increase by. Many plants reported to be useful for the treatment of diabetes mellitus in ayurvedic medicine, are being tested for their hypoglycemic activity in experimental animals Lagerstroemia flos- reginae is one such plant commonly found as shade trees in Kerala. In Ayurveda both root and leaves are used in the treatment of diabetes. The main objective of this study was to assess the antidiabetic effect of the alcohol extracted leaves of Lagerstroemia flos- reginae in alloxan induced diabetic rats in terms of controlling blood glucose level, lipid profile, bilirubin, uric acid in serum and lipid peroxides and glutathione in the liver of the experimental animals. The present study has been undertaken to observe the protective effect of the active constituents of Lagerstroemia flos- reginae leaf extracts against alloxan induced diabetes in experimental animal model. The activity of the active constituents was compared with Daonil –a standard drug.
목차
Abstract 1. Introduction 2. Materials and Methods 2.1. Plant Material 2.2. Preparation of Alcoholic Extract 2.3. Preparation of Standard Drug 2.4. Preparation of Diabetic Rats 2.5. Estimation of Glucose 2.6. Estimation of Triglyceride (GPO – POD- ESPASmethod) 2.7. Estimation of Cholesterol 2.8. Estimation Of HDL CholesteroI 2.9. Estimation Of Uric Acid 2.10. Estimation of Bilirubin (Jendrassik – Grof Method) 2.11. Tissue Estimation 2.13. Estimation of Lipid Peroxide 2.14. Estimation of Glutathione 2.15. Estimation of Proteins in Liver Homogenised 3. Results 4. Conclusion References
키워드
Diabetes MellitusLagerstroemia flos- reginae
저자
Merlin Jayalal .L .P [ Department of Biochemistry, Bharathidasan college of Arts and Science, Ellispettai, Erode-638116, Tamilnadu, India ]
Corresponding author
조선대학교 기초과학연구원 [The Natural Science Research Institute of Chosun]
설립연도
2008
분야
자연과학>자연과학일반
소개
본 연구원은 기초과학을 진흥하기 위한 연구·교육 및 그 보급을 목적으로 한다. 이 목적을 달성하기 위하여 다음 각 호의 사업을 수행한다.
1. 기초과학 제 분야에 관한 조사와 연구
2. 기초과학에 관한 학술행사(학술대회, 학술세미나, 심포지엄, 초청강연회 등) 개최
3. 학문후속세대 및 일반인을 위한 기초과학 교육
4. 기관지『조선자연과학논문지』 발간
5. 『자연과학연구총서』, 『자연과학번역총서』 등 단행본 발간
6. 기타 본 연구원의 목적과 관련된 사업
간행물
간행물명
통합자연과학논문집(구 조선자연과학논문집) [Journal of Integrative Natural Science]