Earticle

초록

영어

An analytical method for the determination of flumequine in meats was developed and validated using high-performanceliquid chromatography with fluorescence detection. The samples were mixed with sodium sulfate and extracted with ethylacetate. After clean-up, the residues were dissolved in mobile phase. The calibration curves showed high linearity (r2=0.9979)within the concentration range of 0.1-1.0mg/kg. The limit of detection and limit of quantification were validated at 0.005 and0.017 mg/kg, respectively. The recoveries in fortified meats ranged from 90.8 to 101.1%. The method was then validated incorrespondence with the CODEX guidelines for flumequine residue in meats. Herein we monitored 150 samples of meats thatwere purchased in Korea (Seoul, Busan, Daegu, Daejeon, and Gwangju). Among the tested samples, flumequine was detectedin 1 of beef and 1 of pork at levels in the range of 0.048-0.080mg/kg. Overall, the flumequine residues in the tested sampleswere within the Maximun residue limit.

한국어

플루메퀸의 분석은 시료를 ethyl acetate로 추출 농축한 후 이농축액에 acetonitrile과 n-hexane을 가하여 분리하고, 분리된 aceto-nitrile층을 농축하였다. 이를 이동상에 녹여 여과한 후 C18 컬럼을이용한 HPLC-FLD로 분석하였다. 분석법은 표준물질 0.1-1.0mg/kg의 농도범위에서 직선성(r2=0.9979)을 나타냈으며, 검출한계는0.005 mg/kg, 정량한계는 0.017 mg/kg이었다. 또한 회수율은 쇠고기에서 90.8-96.7%, 돼지고기에서 96.4-96.6%, 닭고기에서 94.0-101.1%이었으며, 상대표준편차(RSD)는 쇠고기, 돼지고기, 닭고기에서 각각 5.3-8.6%, 3.0-6.8%, 3.1-4.1%이었다. 확립된 분석방법으로 유통 중인 식육(쇠고기, 돼지고기, 닭고기) 150건을 전국지역(서울, 부산, 대구, 대전, 광주)별로 수거하여 플루메퀸의 잔류 실태를 조사한 결과, 쇠고기 1건(0.080 mg/kg), 돼지고기 1건(0.048 mg/kg)에서 검출되었으며, 조사한 식육 150건의 플루메퀸 잔류량은 모두 잔류허용기준 이하의 수준이었다.

목차

Abstract
 서 론
 재료 및 방법
 결과 및 고찰
 요 약
 문 헌

키워드

저자

• 국주희 [ Ju-Hee Kuk | 광주지방식품의약품안전청(Gwangju Regional Korea Food and Drug Administration) ]
• 고용석 [ Yong-Seok Ko | 광주지방식품의약품안전청(Gwangju Regional Korea Food and Drug Administration) ]
• 김용훈 [ Yong-Hoon Kim | 서울지방식품의약품안전청(Seoul Regional Korea Food and Drug Administration) ]
• 윤창용 [ Chang-Yong Yoon | 국립독성과학원(National Institute of Toxicological Research) ]
• 선남규 [ Nam-Kyu Sun | 대전지방식품의약품안전청(Daejeon Regional Korea Food and Drug Administration) ]
• 김은정 [ Eun-Jung Kim | 광주지방식품의약품안전청(Gwangju Regional Korea Food and Drug Administration) ]
• 서지우 [ Jee-Woo Seo | 광주지방식품의약품안전청(Gwangju Regional Korea Food and Drug Administration) ]
• 박지원 [ Ji-Won Park | 광주지방식품의약품안전청(Gwangju Regional Korea Food and Drug Administration) ]
• 강길진 [ Kil-Jin Kang | 식품의약품안전청 영양기능식품국(Korea Food and Drug Administration) ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국식품과학회지 [Korean Journal of Food Science and Technology]

• 간기

  격월간

• pISSN

  0367-6293

• 수록기간

  1969~2011

• 십진분류

  KDC 574 DDC 664