Earticle

초록

영어

A mathematical model using local thermodynamic equilibrium isotherms for adsorption in encapsulated adsorbent is proposed in order to optimize the design parameters in situ bioproduct separation process. The model accurately follows the experimental data on the adsorption of berberine, secondary metabolite produced in Thaictrum rugosum plant cell culture. The adsorption rate on encapsulated adsorbent is compared with that on alginate-entrapped adsorbent. The result shows that the higher loading capacity in encapsulated adsorbent is mainly due to the increase in the maximum solid phase concentration. Based on the adsorption rate and loading capacity, the encapsulated adsorbent would be more useful than the entrapped adsorbent when used in situ bioproduct separation process. Design parameters in situ bioproduct separation process, such as the size of the capsule, membrane thickness, the ratio of capsule volume to bulk volume, the ratio of single capsule volume to total capsule volume and the adsorbent content in the capsule, are evaluated by using the model. The ratio of single capsule volume to total capsule volume is the most effective parameter for adsorption of berberine on encapsulated adsorbent.

목차

ABSTRACT
 INTRODUCTION
 NOMENCLATURE
 ACKNOWLEGEMENT
 RESULTS AND DISCUSSION
  Adorption of Berberine
  Preoaration of Adsorbent
  Entrapped Adsorbent
  Encapsulated Adsorbent
  Adsorber Unit
 THEORETICAL MODEL 
  Model Equations
 MATERIALS AND METHODS
  Materials 
  Subscripts
 REFERENCES

저자

• 최정우 [ Jeong-Woo Choi | 서강대학교 화학공학과 ] Corresponding Author
• 조상원 [ Sang-Won Cho | 서강대학교 화학공학과 ]
• 이원홍 [ Won-Hong Lee | 서강대학교 화학공학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  KSBB Journal

• 간기

  격월간

• pISSN

  1225-7117

• 수록기간

  2009~2013

• 십진분류

  KDC 476 DDC 576