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수원지역 의과대학 치과에 내원한 환자의 영구치 발거실태에 관한 연구
대한치과위생학회 대한치과위생학회지 제18권 제1호 2016.07 pp.55-65
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4,200원
Our study focused on etiologic factors for tooth extraction and extraction age for patients in medical clinics of suwon area. 3,357 teeth were selected for this study extracted between January, 1, 2010 to December, 31, 2012. The etiologic factors for teeth extraction retrospectively classified to KCD, and the results were as follows. 1. Periodontal diseases 37.5%, dental caries 29.0%, pericoronitis and impacted teeth 21.5%, radicular cyst 5.5%, fracture of teeth 3.4%, and the orthers 3.1%. 2. According to the age, pericononitis and impacted teeth was most prevalent before fourth decade and the most prevalent after that was periodontal diseases. Extraction caused by dental caries was commonly the second most prevalent in all age groups(p<.05). 3. According to sex, extraction by periodontal diseases was prevalent in male(39.6%), and that by dental caries was prevalent in female(34.7%)(p<.05). 4. In comparison of upper and lower jaw, both jaws were prevailed by periodontal diseases. and the extraction by radicular cyst was prevalent in lower jaw(7.9%) in contracst to upper jaw(3.4%)(p<.05). 5. According to tooth type, all extracted teeth was caused by periodontal diseases except upper and lower 3rd molar. Among them, the most frequent tooth type was lower second molar(8.2%) and the least frequent tooth type was lower canine(2.2%)(p<.05). 6. Male was earlier(46.1years) than female(48.8years) in consideration of extraction age. The earlest extracted tooth was lower first molar(52.1years) and the latest extracted one was lower canine(68.1years) except wisdom teeth(p<.05).
노년기 음주자의 치아발거 필요와 관련된 요인 KCI 등재
중소기업융합학회 융합정보논문지(구 중소기업융합학회논문지) 제9권 제12호 2019.12 pp.227-235
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4,000원
본 연구는 2013-2015년도에 질병관리본부에서 실시한 국민건강영양조사 자료를 활용하여 만 65세 이 상의 발거가 필요한 치아를 보유한 음주노인 1,865명을 대상으로 했다. 치아발거필요 관련요인을 결과변수로 한 분석결과, 음주노인의 남성에서, 소득이 더 낮을수록, 흡연자에서, 본인인지구강건강상태 나쁨에서, 구강위 생용품 사용안함에서 치아를 발거해야 할 위험도가 높았으며, 통계적으로 유의한 차이를 보였다. 음주노인의 치아발거 위험요인을 미리 파악하여 치아상실을 조기에 예방하고 잔존치아의 수명을 최대한 연장하기 위해서 는 음주문화를 개선하고 현재가 아닌 이전 생애주기에서 음주자의 구강건강관리 전략을 모색하고, 국가차원의 통합적 구강보건정책이 추진되어야 할 것이다.
This study was conducted on 1,865 drunk elderly people who had teeth that were over 65 years old. As a result of analysis of factors related to tooth extraction, the higher the income, the lower the income, the higher the risk of having to remove teeth from smokers, poorer oral health status, and no oral hygiene products. The difference was statistically significant. In order to identify the risk factors of tooth extraction for the elderly and prevent tooth loss early and to extend the life of residual teeth as much as possible, it is necessary to improve the drinking culture and seek oral health care strategies in the previous life cycle, not the present, Oral health policy should be pursued.
Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea
[Kisti 연계] 대한구강악안면외과학회 Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol.46 No.1 2020 pp.49-57
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Objectives: This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients. Materials and Methods: This study analyzed dental records from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011-2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were considered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis. Results: The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by penicillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%. Conclusion: The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other countries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.
Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea
[NRF 연계] 대한구강악안면외과학회 대한구강악안면외과학회지 Vol.46 No.1 2020.02 pp.49-57
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Objectives: This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients.Materials and Methods: This study analyzed dental records from the National Health Insurance Service?National Sample Cohort (NHIS?NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011-2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were con-sidered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis.Results: The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by peni-cillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%. Conclusion: The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other coun-tries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.
[Kisti 연계] 대한치주과학회 Journal of periodontal & implant science Vol.47 No.5 2017 pp.264-272
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Purpose: This study evaluated trends in tooth extraction due to acute and chronic periodontal disease (PD) using data from the National Health Insurance Service-National Sample Cohort for 2002-2013. Methods: A random sample of 1,025,340 individuals was selected as a representative sample of the population, and a database (DB) of diagnostic and prescription codes was followed up for 12 years. We used multivariate logistic regression analysis to assess the incidence of total extraction (TE), extraction due to periodontal disease (EPD), and immediate extraction due to periodontal disease (IEPD) according to sociodemographic factors (sex, age, household income, health status, and area of residence). Results: The incidence of tooth extraction was found to be increasing, and at a higher rate for TE in PD patients. In 2002, 50.6% of cases of TE were caused by PD, and this increased to 70.8% in 2013, while the number of cases of IEPD increased from 42.8% to 54.9% over the same period. The incidence rates of extraction due to acute and chronic PD increased monotonically. We found that the incidence rates of TE, EPD, and IEPD were all 2-fold higher among patients with high income levels and those who were not beneficiaries of health insurance. Conclusions: The rates of TE, EPD, and IEPD have been steadily increasing despite dental healthcare policies to expand public health insurance coverage, increasing the accessibility of dental clinics. Moreover, the effects of these policies were found to vary with both income and education levels. Consistent patient follow-up is required to observe changes in trends regarding tooth extraction according to changes in dental healthcare policies, and meticulous studies of such changes will ensure optimal policy reviews and revisions.
[Kisti 연계] 대한치과보철학회 The journal of advanced prosthodontics Vol.8 No.6 2016 pp.511-514
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For patients with systemic diseases who face difficulties visiting dental clinics, wearing fixed partial denture in the anterior region on the same day of tooth extraction can reduce the total period of treatment and the number of visits, as well as post-treatment psychological effect on the patient.
[Kisti 연계] 대한치의학회 Journal of Korean dental science Vol.9 No.2 2016 pp.69-73
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Clinicians must be able to recognize post-extraction complications and treat them in a timely manner; complications that may potentially be life-threatening require special attention. Although arteriovenous malformation (AVM) is a very rare disorder, it may induce life-threatening hemorrhage during surgical intervention in the pertinent site. The present article examines the diagnosis and treatment modalities of AVM based on the case of a patient who was diagnosed with AVM with continuous bleeding after tooth extraction and who was successfully treated.
Ethnic and racial considerations in dental tooth extraction: a scoping review of current findings
[Kisti 연계] 대한구강악안면외과학회 Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol.52 No.3 2026 pp.139-149
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Dental extractions are among the most frequently performed procedures in dentistry. While anatomical, behavioral, and access-related factors are known to influence extraction outcomes, the role of racial and ethnic characteristics in shaping extraction techniques, preferences, and disparities has not been synthesized. This scoping review aimed to explore and map the existing evidence on how racial, ethnic factors influence dental tooth extraction. A search was conducted across PubMed, Scopus, Google Scholar using a combination of MeSH terms and keywords related to dental extraction, race, ethnicity, anatomy, and sociocultural behavior. The review followed PRISMA-ScR guidelines. A total of 15 studies were included, encompassing anthropological, clinical, forensic, public health perspectives. The review identified key racial anatomical traits (e.g., root morphology, dental arch form, bone density) that affect extraction difficulty, particularly among Caucasoid, Mongoloid, and Negroid populations. Ethnic and cultural factors-health beliefs, care-seeking behavior, and access disparities-played a role in extraction timing and technique. Provider bias, lack of diversity within the dental workforce emerged as contributing factors to inequitable care delivery. Integrating this understanding into dental education, clinical guidelines can support equitable, culturally competent care. Further research is warranted to bridge anatomical evidence with behavioral and structural determinants of extraction disparities.
[Kisti 연계] 대한구강악안면외과학회 Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol.49 No.2 2023 pp.68-74
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Objectives: Drug holidays are suggested to reduce the formation of osteonecrosis in patients under intravenous (IV) bisphosphonates (BPs) therapy. The objectives of this study are to evaluate the incidence of medication-related osteonecrosis of the jaw (MRONJ) following tooth extraction in cancer patients using IV BP, and to assess the effect of drug holiday on the development of MRONJ. Patients and Methods: A manuel search of the patient folders of Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hacettepe University was undertaken to identify cancer patients who used IV BPs and had at least one tooth extraction between 2012 and 2022. Patents' age, sex, systemic condition, the type of BP used, duration of BP used, number of tooth extraction, duration of drug holiday, localization of tooth extraction and incidence of MRONJ were recorded. Results: One hundred nine teeth were removed from 57 jaws in 51 patients. All tooth extractions were performed under perioperative antibiotic prophylaxis and with primary wound closure. The incidence of MRONJ was 5.3%. Stage 1 MRONJ developed in 3 patients (only one had a drug holiday). The median duration of drug holiday was 2 months. No significant difference between the patients with and without a drug holiday and MRONJ development was found (P=0.315). The mean age of patients developed MRONJ was 40.33±8.08 years. A statistically significant difference was found between age and MRONJ development (P=0.002). Conclusion: The effect of a short-term drug holiday on the development of MRONJ may be limited because BPs remain in bone tissue for a long time. Drug holidays should be applied with the approval of an oncologist with other preventive measurements.
The incidence of postoperative hemorrhage after tooth extraction in patients with thrombocytopenia
[Kisti 연계] 대한구강악안면외과학회 Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol.47 No.3 2021 pp.190-196
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Objectives: The risk of bleeding after tooth extraction in thrombocytopenia patients remains unclear. Therefore, the present study aimed to assess the risk of bleeding after tooth extraction in patients with thrombocytopenia. Materials and Methods: The study included 220 patients who had a medical history of thrombocytopenia and underwent tooth extraction (330 teeth). The patients were divided into those who had thrombocytopenia (platelet count <150k) immediately before the tooth extraction, and those who had platelet counts that were between 150k and 250k before the extraction. Bleeding complications were recorded and compared between the patient groups. Results: Of the 220 patients, 130 underwent tooth extractions while having thrombocytopenia (platelet count <150k), and 90 had platelet counts that were between 150k and 250k before tooth extractions. Bleeding complications occurred in 11 patients (5.0%) of the 220 patients. Among those 11 patients with bleeding complications, 10 patients (7.7%) had thrombocytopenia (platelet count <150k) of the 130 patients, and 1 patient (1.1%) had a normal platelet count of the 90 patients. There was a significant difference between the patient groups regarding bleeding after extractions (P<0.001). No significant difference in the incidence of post-extraction bleeding was found between the subgroups by platelet count within the thrombocytopenia group. Conclusion: Thrombocytopenia (platelet count <150k) increases the risk of post-tooth extraction bleeding. Therefore, bleeding control under the proper evaluation of hemostasis and performing delicate tooth extraction procedures using hemostatic plugs is necessary during the tooth extraction of patients with thrombocytopenia.
Ethnic and racial considerations in dental tooth extraction: a scoping review of current findings
[NRF 연계] 대한구강악안면외과학회 대한구강악안면외과학회지 Vol.52 No.3 2026.06 pp.139-149
※ 협약을 통해 무료로 제공되는 자료로, 원문이용 방식은 연계기관의 정책을 따르고 있습니다.
Dental extractions are among the most frequently performed procedures in dentistry. While anatomical, behavioral, and access-related factors are known to influence extraction outcomes, the role of racial and ethnic characteristics in shaping extraction techniques, preferences, and disparities has not been synthesized. This scoping review aimed to explore and map the existing evidence on how racial, ethnic factors influence dental tooth extraction. A search was conducted across PubMed, Scopus, Google Scholar using a combination of MeSH terms and keywords related to dental extraction, race, ethnicity, anatomy, and sociocultural behavior. The review followed PRISMA-ScR guidelines. A total of 15 studies were included, encompassing anthropological, clinical, forensic, public health perspectives. The review identified key racial anatomical traits (e.g., root morphology, dental arch form, bone density) that affect extraction difficulty, particularly among Caucasoid, Mongoloid, and Negroid populations. Ethnic and cultural factors?health beliefs, care-seeking behavior, and access disparities?played a role in extraction timing and technique. Provider bias, lack of diversity within the dental workforce emerged as contributing factors to inequitable care delivery. Integrating this understanding into dental education, clinical guidelines can support equitable, culturally competent care. Further research is warranted to bridge anatomical evidence with behavioral and structural determinants of extraction disparities.
[NRF 연계] 대한구강악안면외과학회 대한구강악안면외과학회지 Vol.49 No.2 2023.04 pp.68-74
※ 협약을 통해 무료로 제공되는 자료로, 원문이용 방식은 연계기관의 정책을 따르고 있습니다.
Objectives: Drug holidays are suggested to reduce the formation of osteonecrosis in patients under intravenous (IV) bisphosphonates (BPs) therapy. The objectives of this study are to evaluate the incidence of medication-related osteonecrosis of the jaw (MRONJ) following tooth extraction in cancer patients using IV BP, and to assess the effect of drug holiday on the development of MRONJ. Patients and Methods: A manuel search of the patient folders of Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hacettepe University was undertaken to identify cancer patients who used IV BPs and had at least one tooth extraction between 2012 and 2022. Patents’ age, sex, systemic condition, the type of BP used, duration of BP used, number of tooth extraction, duration of drug holiday, localization of tooth extraction and incidence of MRONJ were recorded. Results: One hundred nine teeth were removed from 57 jaws in 51 patients. All tooth extractions were performed under perioperative antibiotic prophylaxis and with primary wound closure. The incidence of MRONJ was 5.3%. Stage 1 MRONJ developed in 3 patients (only one had a drug holiday). The median duration of drug holiday was 2 months. No significant difference between the patients with and without a drug holiday and MRONJ development was found (P=0.315). The mean age of patients developed MRONJ was 40.33±8.08 years. A statistically significant difference was found between age and MRONJ development (P=0.002). Conclusion: The effect of a short-term drug holiday on the development of MRONJ may be limited because BPs remain in bone tissue for a long time. Drug holidays should be applied with the approval of an oncologist with other preventive measurements.
The incidence of postoperative hemorrhage after tooth extraction in patients with thrombocytopenia
[NRF 연계] 대한구강악안면외과학회 대한구강악안면외과학회지 Vol.47 No.3 2021.06 pp.190-196
※ 협약을 통해 무료로 제공되는 자료로, 원문이용 방식은 연계기관의 정책을 따르고 있습니다.
Objectives: The risk of bleeding after tooth extraction in thrombocytopenia patients remains unclear. Therefore, the present study aimed to assess the risk of bleeding after tooth extraction in patients with thrombocytopenia. Materials and Methods: The study included 220 patients who had a medical history of thrombocytopenia and underwent tooth extraction (330 teeth). The patients were divided into those who had thrombocytopenia (platelet count <150k) immediately before the tooth extraction, and those who had platelet counts that were between 150k and 250k before the extraction. Bleeding complications were recorded and compared between the patient groups. Results: Of the 220 patients, 130 underwent tooth extractions while having thrombocytopenia (platelet count <150k), and 90 had platelet counts that were between 150k and 250k before tooth extractions. Bleeding complications occurred in 11 patients (5.0%) of the 220 patients. Among those 11 patients with bleeding complications, 10 patients (7.7%) had thrombocytopenia (platelet count <150k) of the 130 patients, and 1 patient (1.1%) had a normal platelet count of the 90 patients. There was a significant difference between the patient groups regarding bleeding after extractions (P<0.001). No significant difference in the incidence of post-extraction bleeding was found between the subgroups by platelet count within the thrombocytopenia group. Conclusion: Thrombocytopenia (platelet count <150k) increases the risk of post-tooth extraction bleeding. Therefore, bleeding control under the proper evaluation of hemostasis and performing delicate tooth extraction procedures using hemostatic plugs is necessary during the tooth extraction of patients with thrombocytopenia.
Healing pattern of the mucous membrane after tooth extraction in the maxillary sinus
[Kisti 연계] 대한치주과학회 Journal of periodontal & implant science Vol.41 No.1 2011 pp.23-29
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Purpose: To investigate the healing pattern of the mucous membrane after tooth extraction necessitated by periodontal disease in the maxillary sinus. Methods: One hundred and three patients with 119 maxillary sinuses were investigated. Before implant placement, cone-beam computed tomography (CT) scanning was performed. The causes of extraction, the time elapsed since extraction, smoking, periodontal disease in adjacent teeth, and gender were recorded. In addition, the thickness of the mucous membrane of the maxillary sinus and the height of residual alveolar bone at the extracted area were calculated from CT images. Results: The thickness of the mucous membrane in the periodontal disease group ($3.05{\pm}2.71\;mm$) was greater than that of the pulp disease group ($1.92{\pm}1.78\;mm$) and the tooth fracture group ($1.35{\pm}0.55\;mm$; P<0.05). The causes of extraction, the time elapsed since extraction, and gender had relationships with a thickening of the mucous membrane of the maxillary sinus (P<0.05). In contrast, the height of the residual alveolar bone at the extracted area, periodontal disease in adjacent teeth, and smoking did not show any relation to the thickening of the mucous membrane of the maxillary sinus. Conclusions: The present study revealed distinct differences in healing patterns according to the causes of extraction in the maxillary sinus, especially periodontal disease, which resulted in more severe thickening of the mucous membrane.
Novel Non-Submerged Implants Replacement of Mandibular Tooth Extraction Sites in Beagle Dogs
[Kisti 연계] 한국임상수의학회 한국임상수의학회 학술대회논문집 2007 p.102
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Factors affecting maxillary sinus pneumatization following posterior maxillary tooth extraction
[Kisti 연계] 대한치주과학회 Journal of periodontal & implant science Vol.51 No.4 2021 pp.285-295
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Purpose: The aims of the present study were 1) to quantitatively evaluate the extent of sinus pneumatization and 2) to determine the factors affecting sinus pneumatization. Methods: Based on implant treatment records, a list of patients who underwent implant placement on the posterior maxilla was obtained. Among them, patients with pre-extraction and post-extraction (before implant placement) panoramic radiographs were selected. After excluding radiographs with low resolution and image distortion, the radiographs before and after extraction were superimposed using computer software. Subsequently, the extent of sinus pneumatization (the vertical change of the sinus floor) was measured. Simple and multiple mixed models were used to determine the factors affecting sinus pneumatization. Results: A total of 145 patients were eligible for the present investigation. The average extent of sinus pneumatization was 1.56±3.93 mm at 176 tooth sites. Male sex, single tooth extraction, extraction of an endodontically compromised tooth, a class I root-sinus relationship, and sinus membrane thickening >10 mm favored pneumatization, but without statistical significance. The maxillary second molar presented the greatest pneumatization (2.25±4.39 mm) compared with other tooth types. This finding was confirmed in the multiple mixed model, which demonstrated a statistically significant impact of the extraction of a second molar compared with the extraction of a first premolar. Conclusions: Maxillary sinus pneumatization was 1.56±3.93 mm on average. The extraction of a second molar led to the greatest extent of pneumatization, which should be considered in the treatment plan for this tooth site.
[Kisti 연계] 대한구강악안면방사선학회 Imaging science in dentistry Vol.47 No.1 2017 pp.45-50
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Purpose: The aim of this study was to investigate the incidence of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after tooth extraction in patients with osteoporosis on oral bisphosphonates in Korea and to evaluate local factors affecting the development of BRONJ. Materials and Methods: The clinical records of 320 patients who underwent dental extraction while receiving oral bisphosphonates were reviewed. All patients had a healing period of more than 6 months following the extractions. Each patient's clinical record was used to assess the incidence of BRONJ; if BRONJ occurred, a further radiographic investigation was carried out to obtain a more definitive diagnosis. Various local factors including age, gender, extraction site, drug type, duration of administration, and C-terminal telopeptide (CTx) level were retrieved from the patients' clinical records for evaluating their effect on the incidence of BRONJ. Results: Among the 320 osteoporotic patients who underwent tooth extraction, 11 developed BRONJ, reflecting an incidence rate of 3.44%. Out of the local factors that may affect the incidence of BRONJ, gender, drug type, and CTx level showed no statistically significant effects, while statistically significant associations were found for age, extraction site, and duration of administration. The incidence of BRONJ increased with age, was greater in the mandible than the maxilla, and was associated with a duration of administration of more than 3 years. Conclusion: Tooth extraction in patients on oral bisphosphonates requires careful consideration of their age, the extraction site, and the duration of administration, and close postoperative follow-up should be carried out to facilitate effective early management.
[Kisti 연계] 대한치의학회 Journal of Korean dental science Vol.7 No.2 2014 pp.94-98
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Numerous oral and maxillofacial surgeons have found facial space infections after tooth extraction. Most of these infections can be managed easily, but some of them could be life-threatening. Among the facial infections, temporal space infections are rare. Most temporal space infections could be observed as secondary to maxillary third molar infections, maxillary sinusitis, and maxillary sinus fractures. Note, however, that there are insufficient studies on temporal space abscess due to mandibular second molars, especially with acupuncture. A 74-year-old female came to our hospital with severe trismus and facial swelling on the right temporal, buccal, posterior auricular, and cervical regions. The patient had undergone extraction of tooth #47 secondary to dental caries by a general dentist about a month ago. After the dental procedure, the patient had been treated with acupuncture therapy around the right temporomandibular joint area at the oriental medicine clinic. We performed emergency incision and drainage under general anesthesia and started antibiotic treatment with IV ampicillin/sulbactam 3 g every 24 hours and vancomycin 1 g every 24 hours for 5 days. The patient's symptoms subsided and ultimately disappeared. Temporal space abscess after mandibular molar extraction is quite rare. In this case, the spreading mechanism against gravity is considered to be acupuncture therapy.
Effect of warfarin discontinuation on the incidence of postoperative bleeding in tooth extraction
[Kisti 연계] 대한구강악안면외과학회 Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol.46 No.4 2020 pp.228-234
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Objectives: The number of patients undergoing oral anticoagulant therapy for cardiovascular and cerebrovascular disease is increasing. However, the risk of bleeding after tooth extraction in patients receiving warfarin is unclear. Here, we assess the risk of bleeding after tooth extraction in patients on warfarin. Materials and Methods: The study included 260 patients taking warfarin who underwent tooth extraction (694 teeth). The patients were divided into those whose teeth were extracted while they were taking warfarin, those who discontinued warfarin before extraction, and those who underwent extraction while receiving heparin bridging therapy. Bleeding complications in the two groups were compared. Results: Of the 260 patients, 156 underwent extraction while taking warfarin, 70 stopped taking warfarin before extractions, and 34 received heparin bridging therapy and stopped taking either medication before extractions. Bleeding complications occurred in 9 patients (3.5%) and 9 tooth sites (1.3%). Among the 9 patients with bleeding complications, 6 underwent extraction while taking warfarin, 2 stopped warfarin before extraction, and 1 underwent extraction after receiving heparin bridging therapy. No significant difference was seen between patient groups regarding bleeding after extractions (P=0.917). Conclusion: Warfarin use does not increase the risk of post-extraction bleeding and can therefore be continued during tooth extraction.
Alteration of LAR-RPTP Expression in the Rat Trigeminal Ganglion after Tooth Extraction
[Kisti 연계] 대한구강생물학회 International journal of oral biology Vol.36 No.4 2011 pp.167-172
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LAR-RPTP (leukocyte common antigen-related receptor protein tyrosine phosphatase) is an important regulator in the nervous system, but little is known about its expression pattern in rat trigeminal ganglion (TG) neurons. To examine whether LAR-RPTP is expressed in the TG in the current study, we sacrificed rats at 0, 7, 10 and 56 day postpartum (dpp) and a second group of rats at 3 and 5 days after an experimental tooth extraction as a TG injury model. RT-PCR was then used to determine the level of LAR-RPTP expression in the TG and immunohistology was employed to detect the subcellular localization of the protein. The mRNA expression of LAR-RPTP during the developmental stages in the TG was found to gradually increase. After experimental tooth extraction however, these transcript levels had significantly decreased at three days. LAR-RPTP protein signals in the TG were found to be cytoplasmic in the normal animals but interestingly, at five days after an experimental tooth extraction, these signals were rare. These results indicate that LAR-RPTP may be regulated during both the developmental as well as regenerative processes that take place in the TG. This further suggests that LAR-RPTP is not only involved in primary axonogenesis but possibly also in the molecular control of axons during TG repair.
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