Earticle

배경: 운동은 운동기술을 습득하는 과정에서 학습 및 경험을 통해 뇌세포 생성에 영향을 미치며, 뇌기능 향상 에 도움이 된다. 뇌기능을 분석하는 방법인 뇌파의 활성도를 통해 운동에 어떠한 영향을 미치는지를 과학적으로 검증 이 필요하다. 목적: 적합한 환경에서 복합적이고 기능적인 줄 사다리 운동을 적용하였을 때 뇌파 활성에 미치는 긍정 적인 효과를 과학적으로 규명하고자 한다. 방법: 남자대학생 30명을 모집 후 줄사다리운동집단, 트레드밀운동집단, 통 제집단으로 나누어 10주간 운동을 적용하여 반복측정하였다. 결과: 운동 적용 시 알파파의 좌측 전전두엽에서 그룹 간 에 통계적으로 유의한 변화가 나타났다(p < .05). 결론: 규칙적인 운동적용 시 뇌파에 긍정적인 영향을 미치지만, 복잡 한 패턴을 적용하여 하지의 기능적 움직임을 만들어내는 줄 사다리 운동이 전통적인 유산소운동과 비교하여 뇌기능에 좋은 영향을 미친다고 볼 수 있다.

Background: Exercise influences the generation of brain cells through learning and experience in the process of acquiring motor skills and helps improve brain function. It is necessary to scientifically verify how brain wave activity, a method of analyzing brain function, affects movement. Purposes: We scientifically identify the positive effects on EEG activity when applying complex functional linear ladder movements in an appropriate environment. Methods: After recruiting 30 male university students, we divided them into a linear ladder exercise group, a treadmill exercise group, and a control group, and exercise was applied and measured repeatedly for ten weeks. Results: There was a statistically significant change between groups in the left prefrontal lobe of alpha waves when exercise was applied (p < .05). Conclusions: Although exercise has a positive effect on EEG, line ladder exercise, which applies a complex pattern and produces more leg movement, appears to have a better impact on brain function than traditional aerobic exercise.

Objective: To assess whether performing exercises during hemodialysis reduces the risk of developing intradialytic hypotension and enhances exercise capacity in patients with chronic kidney disease.Methods: This study included patients aged ≥18 years undergoing hemodialysis. Participants performed exercises using a portable lower extremity ergometer during hemodialysis sessions for 3 weeks. Data regarding walking distance, knee strength, quality of life, fat-free mass, arterial pressure, blood pressure, heart rate, frequency of intradialytic hypotension, fatigue, and duration of hemodialysis were collected and analyzed.Results: Significant improvements in walking distance and knee strength were observed following the implementation of exercise training during hemodialysis. Although there was no significant reduction in the frequency of intradialytic hypotension, a decreasing trend was noted. Other parameters such as quality of life and fatigue did not show significant changes.Conclusion: Using a portable ergometer during hemodialysis improved exercise capacity and knee strength in patients with chronic kidney disease. There was a trend toward reduced intradialytic hypotension, suggesting potential cardiovascular benefits. Further research with larger sample sizes is needed to confirm these findings.

Objective To determine if assistive ergometer training can improve the functional ability and aerobic capacity of subacute stroke patients and if functional electrical stimulation (FES) of the paretic leg during ergometer cycling has additional effects.Methods Sixteen subacute stroke patents were randomly assigned to the FES group (n=8) or the control group (n=8). All patients underwent assistive ergometer training for 30 minutes (five times per week for 4 weeks). The electrical stimulation group received FES of the paretic lower limb muscles during assistive ergometer training. The six-minute walk test (6MWT), Berg Balance Scale (BBS), and the Korean version of Modified Barthel Index (K-MBI) were evaluated at the beginning and end of treatment. Peak oxygen consumption (Vo2peak), metabolic equivalent (MET), resting and maximal heart rate, resting and maximal blood pressure, maximal rate pressure product, submaximal rate pressure product, submaximal rate of perceived exertion, exercise duration, respiratory exchange ratio, and estimated anaerobic threshold (AT) were determined with the exercise tolerance test before and after treatment.Results At 4 weeks after treatment, the FES assistive ergometer training group showed significant improvements in 6MWT (p=0.01), BBS (p=0.01), K-MBI (p=0.01), Vo2peak (p=0.02), MET (p=0.02), and estimated AT (p=0.02). The control group showed improvements in only BBS (p=0.01) and K-MBI (p=0.02). However, there was no significant difference in exercise capacity and functional ability between the two groups.Conclusion This study demonstrated that ergometer training for 4 weeks improved the functional ability of subacute stroke patients. In addition, aerobic capacity was improved after assisted ergometer training with a FES only.

Objective To assess the effect of combined hospital and home-based exercise programs on functional capacity and quality of life (QoL) among uncorrected atrial septal defect-associated pulmonary arterial hypertension (ASD-PAH) patients. Methods This study was a randomized controlled trial with uncorrected ASD-PAH patients as the subjects. They were allocated randomly into control and exercise groups. Exercise group subjects performed hospital and home-based exercise programs, completing baseline 6-minute walking test (6MWT) and EQ-5D-3L QoL test (Utility Index and EQ-VAS scores), and were followed up for 12 weeks. The primary outcomes were 6MWT distance and EQ-5D-3L score at week 12. The N-terminal pro B-type natriuretic peptide (NT-proBNP) level was also assessed. A repeated-measure ANOVA was performed to detect endpoint differences over time. Results The exercise group contained 20 subjects and control group contained 19. In total, 19 exercise group subjects and 16 control group subjects completed the protocol. The 6MWT distance, Utility Index score, and EQ-VAS score incrementally improved significantly in the exercise group from baseline until week 12, with mean differences of 76.7 m (p<0.001), 0.137 (p<0.001) and 15.5 (p<0.001), respectively. Compared with the control group, the exercise group had significantly increased 6MWT distance and utility index score at week 12. The EQ-VAS score increased in the exercise group at week 12. The NTproBNP level decreased at week 12 in the exercise group. Conclusion Combined hospital and home-based exercise program added to PAH-targeted therapy, improving functional capacity and QoL in uncorrected ASD-PAH patients.

Objective: The aim of this study is to investigate the effect of hamstring eccentric exercise on pain and functional activity in patients with chronic low back pain. Design: Randomized controlled trial Methods: Participants comprised 27 subjects with back pain persisting for 3 months. They were randomly assigned to the experimental group (Eccentric exercise: n=13) and the control group (Stretching: n=14). The experimental group performed gastrocnemius, iliopsoas, and quadratus lumborum stretching along with hamstring eccentric exercise, while the control group engaged in the same stretches along with hamstring stretching. The eccentric exercise for the hamstrings was Nordic curl exercise. Each group practiced for 1 hour a day, 3 times a week, for 4 weeks. Pain, disability index, balance, and hamstring length were measured. Results: Significant differences were observed in the comparison of changes in back pain, back disability index, and hamstring length before and after exercise within each group (p<0.05). The balance ability of the experimental group showed a difference before and after exercise (p<0.05), whereas no significant difference in the control group. There were no significant differences in back pain and hamstring length between the groups. Changes in back disability index and balance ability significantly increased in the experimental group compared to the control group (p<0.05). Conclusion: Hamstring eccentric exercise using Nordic curls has a positive effect on back pain, back disability index, balance ability, and hamstring length changes.

Objective: Weakness of the rotator cuff and shoulder muscles in patients with lateral elbow tendinopathy leads to elbow pain and functional impairment. In this study, we investigated how shoulder muscle exercise therapy could affect functional levels, grip strength, and pain in patients with lateral elbow tendinopathy. Design: Randomized controlled trials, assessor blind Methods: We enrolled 25 patients diagnosed with lateral elbow tendinopathy, who had experienced pain at a rate of ≥4 on the visual analog scale for at least 6 weeks, and exhibited full shoulder joint range of motion. After baseline assessment, we randomly assigned the participants into a shoulder muscle and a general exercise therapy group. Both groups performed a prescribed exercise program twice a week over 6 weeks for a total of 12 sessions. We assessed functional levels using the Korean versions of the PRTEE and Quick-DASH questionnaires and evaluated grip strength. Finally, we measured pain intensity using a visual analog scale. Results: Both groups displayed significant improvements in functional level, grip strength, and pain (p<0.05). Significant differences could be observed between the groups in functional level and pain (p<0.05). Both the combination and general exercise therapy groups exhibited improvements in functional level, grip strength, and pain. Conclusions: The results of this study indicate that a combination of shoulder muscle and general exercise therapies is more effective than general exercise therapy alone in patients with lateral elbow tendinopathy. Therefore, a combination of shoulder muscle and general exercise therapies might serve as a more effective intervention strategy for lateral elbow tendinopathy management.

Purpose: This study examined the effects of a physical stability exercise program on the functional movement and balance of middle school volleyball players to provide future management and training data to improve the performance of volleyball players. Methods: The subjects were 20 volleyball players from Y Middle School in Mokpo. The results of comparing and analyzing the effects of the physical stability exercise program on the functional movement and balance of middle school volleyball players for 10 weeks are as follows. Results: The number of participants who showed power and agility (p<0.01) was increased significantly, and the response time was shortened significantly (p<0.01). On the evaluation of functional movement, the total score showed a significant difference between the pre-test at 10.90±1.30 points and the post-test at 13.81±.60 (p<0.001). The subjects' balance showed a significant difference from 84.11±7.53 to 97.65±8.47 (p<0.001), and the Right Composite Score showed a significant difference from 83.74±6.64 to 97.27±8.48 (p<0.001). Conclusion: The application of a physical stability exercise program for 10 weeks is effective in improving the speed, agility, functional movement, and balance to volleyball players who are weakened and at risk of injury. This is believed to prevent or reduce injury.

PURPOSE: The aim of this study was to investigate the effects of exercise intensity and initial timing on functional recovery following sciatic nerve injury in rats. METHODS: Total of 80 Sprague-Dawley rats was used and randomly divided 6 groups. Under deep anesthesia, the sciatic nerve was nipped by adapted hemostatic tweezers for 30 seconds and the injured nerve was transparent under naked eyes. Acute exercise groups was applied treadmill after sciatic nerve crush injury during 5days with three type intensity. Late exercise groups was also applied treadmill during 5 days with three type intensity after 5 days break. Values of sciatic functional index were measured and analyzed in each group after exercise period. RESULTS: The sciatic functional index values between control groups 1, acute low-intensity group, acute middle-intensity group in acute phase showed statistical significant (p<.05). The sciatic functional index values between control groups 2, late low-intensity group, late middle-intensity group and late high-intensity in late phase showed statistical significant (p<.05). The comparison in acute and late phase, sciatic functional index values of each low-intensity group and each high-intensity group showed statistical significant (p<.05). CONCLUSION: Whether at acute or late phase, treadmill exercise as a therapy obtained beneficial effects of functional recovery and exercise training at low speed is more beneficial effects on the recovery of motor function in acute phase.

Objective: Carpal tunnel syndrome is one of the most common upper extremity compressive nerve disorders in modern people. Various conservative treatments such as taping, exercise, and electrotherapy have been applied to carpal tunnel syndrome and their effectiveness has been proven. This study aims to determine whether home exercise combined with taping is effective for pain and functional disability in patients with carpal tunnel syndrome. Design: Randomized controlled study Methods: 21 patients were recruited and were randomly divided into HEx+T (Home exercise+taping) group (n=10) and HEx (Home exercise) group (n=11). All participants performed Home exercise(tendon and neural gliding exercise) 5 times a week for 6 weeks. Additionally, subject in the HEx group, taping was applied over the wrist and forearm during the training period. Wrist pain was measured by VAS (Visual Analogue Scale). Functional disability was measured using a BCTSQ(The Boston Carpal Tunnel Syndrome Questionnaire). Results: Both the HEx+T group and the HEx group showed a significant improvement in wrist pain(p<0.05), and the HEx+T group showed a more significant decrease in pain than the HEx group(p<0.05). There was a significant improvement in both groups in functional disability (p<0.05), and the HEX+T group showed more improvement than the HEX group(p<0.05). Conclusions: This study suggests that home exercise combined with taping is effective for pain and functional disability in patients with carpal tunnel syndrome.

Objective: Flexed posture commonly increases with age in older adults and is characterized by kyphosis and forward head posture. Changes in the posture with age affect both balance and mobility. This study was conducted to examine the effects of a cervical stabilization exercise for community-dwelling older adults to improve balance. Design: Two groups pretest-posttest design. Methods: Fifty older adults were randomly assigned into the cervical stabilization exercise group (n=24) and control group (n=25). The cervical stabilization exercise group (n=24) participated in group exercise for 60 minutes twice a week over 4 weeks. Timed up and go test (TUG), four square step test (FSST), functional reach test (FRT), postural sway, cervical range of motion (CROM), proprioception, craniovertebral angle (CVA) were evaluated before and after the intervention. Results: TUG, FSST, FRT, CROM, Proprioception, CVA showed significantly greater improvement, compared with a control group (p<0.05). Conclusions: Findings of this study demonstrate that cervical stabilization exercise can help improve not only neck functional capacities but also balance. Therefore, it may be used as an effective balance exercise program for community-dwelling older adults.

Purpose: This study examined the effects of stretching and strengthening exercises on the pain, pelvic tilt (PT), functional disability, and balance of patients with chronic lower back pain (CLBP). Methods: A total of 42 patients with CLBP were randomly divided randomly into either experimental group I (EG I, n=21), who received stretching exercise, or experimental group II (EG II, n=21), who received strengthening exercise. Both interventions were applied three times a week for eight weeks. Assessments were made with a visual analogue scale (VAS), PT, Oswestry disability index (ODI), and Berg's balance scale (BBS) before and after the eight weeks intervention period. A paired t-test was conducted to compare the within-group changes before and after the intervention. An independent t-test was used compare the between-group difference. The statistical significance level was set to ${\alpha}=0.05$ for all variables. Results: The EG I and II showed significant within-group changes in the VAS, PT, ODI, and BBS (p<0.05). The changes in VAS, PT, ODI, and BBS were similar regardless of the exercise form. Conclusion: In this study, the application of stretching and strengthening exercise for subjects who complain of CLBP was effective in changing the level of pain, PT, functional disability, and balance.

Background: There is abundance of studies on the decrease in body fat through limited calorie intake or exercise; however, studies focusing simultaneously on functional foods and exercise are rare. This study was aimed to identify the effects of combination of a functional beverage and exercise on body composition and biochemical metabolic profiles. Method: Eighty-one healthy volunteers (69 females aged 19 to 50 years and 12 males aged 19 to 55 years), who maintained their body weight stable with 23 or higher in BMI (kg/$m^2$) and 25% or higher body fat for the last three months, were recruited in the study through written advertisement. All the subjects gave their informed consent, and the study was conducted in accordance with the Declaration of Helsinki. The study design was a randomized double-blind placebo-controlled parallel group design. All participants were given 12-week programed-exercise, which was performed 3 times a week. One bottle (100 ml) of test (Garcinia cambogia 300 mg, L-carnitine 20 mg, Soy peptide 1,000 mg) or placebo solution was given daily 30 min before each session of programed-exercise. BMI (body mass index), %fat, local fat amount (visceral and mid-thigh), waist circumference, skin fold thickness and some biochemical metabolic parameters like glucose, insulin and free fatty acids, etc in the blood were measured and compared before and after 12-week intervention within groups as well as between groups according to the protocol Results: Twenty six volunteers were dropped out and fifty five volunteers completed the study. At the end of 4, 8, and 12 weeks, approximately 1.98%, 3.00% and 3.50% losses of initial body weight were observed, respectively, in the test group (P<0.01), and 0.29, % ,0.74%, 1.60%, respectively, in the placebo group (P>0.05). BMI changed by 2.40%, 3.41% and 4.46%, respectively, in the test group, and 0.38%, 0.95% and 1.75%, respectively, in the placebo group, at each period of time. The reductions of body weight and BMI were significantly higher in the test group than in the placebo group at each period of time (P<0.05). Conclusions: It is thought that the combination of functional beverage, which contains mostly garcinia cambogia, L-carnitine, and soy peptide, and exercise have synergy effects on reducing body fat.

PURPOSE: The functional limitations in stroke survivors promote sedentary lifestyles and quality of life inadequacies, but there is increasing evidence that this could be minimized by physical exercise. Therefore, this study examined the effects of physical exercise on the quality of life (QoL) and functional capacity (ability to stand up from a sitting position) among stroke survivors drafted from two tertiary hospitals in Osogbo, Nigeria. METHODS: A purposive sampling technique was used to select 21 registered right or left outpatient hemiplegic stroke survivors in a pre- and post-test experimental research design. The research questions were presented using descriptive statistics of frequency, percentage, mean and standard deviation, while an Analysis of Variance (ANOVA) was used to test the study hypothesis at the .05 alpha level for significance. RESULTS: Compared to the baseline (week 0), there were significant increases in the general quality of life, healthy well-being, physical exercise, pain perception, and environmental domains of QOL among the survivors in week four. Moreover, a significant increase was observed in these indices in week eight, compared to week four, except for the pain perception domain. Compared to the baseline, there was a significant decrease in the time it took the stroke survivors to stand up from a sitting position in week four. A significant decrease was observed in this index in week eight compared to week four. CONCLUSION: Marked corridor 20 meters brief walking exercise for eight weeks significantly improved the quality of life and ability to stand up from a sitting position in stroke survivors in Osogbo, Nigeria.

Background: Ankle sprain is one of the most common musculoskeletal injuries in the sports population or during usual daily life activities. The sprain can cause functional ankle instability (FAI), and it is very important to treat FAI. However, the optimum intervention method for FAI has yet to be determined. Objects: This study investigated the impact that virtual reality (VR) training program on balance with ankle kinesio taping for FAI. Methods: Twenty-two people were selected for the study and randomly divided into the experimental (n = 11) and the control group (n = 11). The experimental group had attached kinesio taping on the ankle and then implemented a virtual reality exercise program for 30 minutes a day. Nintendo Wii Fit Plus was used for the VR intervention three times a week for four weeks. The control group performed only two measurements without intervention. Results: There were no statistically significant differences in overall, anterior-posterior (AP), medial-lateral (ML) index of the static balance, and significant differences in overall, AP, ML index of the dynamic balance when taping and VR exercise were applied at the same time (p < 0.05). There were no significant differences in overall and ML index of static and dynamic balance compared with before and after assessment between the experimental and the control group, and found differences in AP index of static and dynamic balance (p < 0.05). Conclusion: Kinesio taping may not influence the balance of FAI as great as people expected. VR approach does not affect the static balance of FAI, but it influences dynamic balance in overall, AP, ML index. The authors suggest that VR-based exercises can be used as an additional concept in clinicians for FAI or as part of a home program because the exercises still have limitations.

Purpose: This study examined the effects of heel raise exercises combined with neuromuscular electrical stimulation (NMES) on the muscle strength and postural control ability of subjects with functional ankle instability (FAI). Methods: Twenty-two subjects with FAI participated in this study. They were assigned randomly to two groups: 11 each in the NMES and the sham-NMES groups. Heel raise exercise was applied, and NMES electrodes were attached to the peroneus longus muscles. The NMES group applied NMES during the heel raise exercise. NMES was applied for 20 minutes during the heel raise exercise. The heel raise exercise was performed four times a week for five weeks. The muscle strength and balance error scoring system (BESS) were measured before and after the intervention. Results: A comparison of before and after the intervention within the groups revealed improved muscle strength in the NMES and Sham-NMES groups, but the BESS was improved under all conditions only in the NMES group. The Sham-NMES group showed no improvement in the unstable support surface. Furthermore, when comparing the amount of change before and after the intervention between the groups, there were significant differences in the total score and unstable support in the BESS and muscle strength. Conclusion: NMES had a positive effect on the functional activities of the functional ankle instability subjects, such as balancing on an unstable support surface during postural control and increasing muscle strength.

Background: Prolonged sitting, low physical activity, and trunk muscle weakness in university students increase the risk of low back pain (LBP), which can alter gait and lower-limb muscle activation. Purpose: To investigate the effects of a 4-week trunk stabilization exercise program on spatiotemporal gait parameters, lower-limb muscle activation, and functional disability in university students with LBP. Study design: Single-group pre-post intervention study. Methods: Twenty-seven university students with LBP performed 16 trunk stabilization exercises once daily for 40 minutes, 5 days per week, for 4 weeks. Gait was assessed using a pressure-sensing walkway to obtain stance phase, single-limb stance, and stride length. Surface electromyography recorded activation of six lower-limb muscles during gait and was normalized to maximum voluntary isometric contraction. Functional disability was evaluated using the Korean version of the Oswestry Disability Index (K-ODI). Pre-post differences were analyzed using repeated measures ANOVA. Results: Stance phase duration significantly decreased, whereas single-limb stance and stride length significantly increased (p<.01). Soleus and biceps femoris activity increased (p<.01), while rectus femoris, tibialis anterior, and popliteus activity decreased (p<.05); gastrocnemius showed a non-significant increase. K-ODI scores decreased from 29.40+/-5.60 to 23.62+/-5.01 (p<.01). Conclusions: A 4-week trunk stabilization program improved gait efficiency, reorganized lower-limb neuromuscular activation, and reduced functional disability in young adults with LBP. Trunk stabilization may be used as a practical, non-invasive intervention in university populations.

The integration of metabolomics and transcriptomics may elucidate the correlation between the genotypic and phenotypic patterns in organisms. In equine physiology, various metabolite levels vary during exercise, which may be correlated with a modified gene expression pattern of related genes. Integrated metabolomic and transcriptomic studies in horses have not been conducted to date. The objective of this study was to detect the effect of moderate exercise on the metabolomic and transcriptomic levels in horses. In this study, using nuclear magnetic resonance (NMR) spectroscopy, we analyzed the concentrations of metabolites in muscle and plasma; we also determined the gene expression patterns of branched chain (alpha) keto acid dehydrogenase kinase complex (BCKDK), which encodes the key regulatory enzymes in branched-chain amino acid (BCAA) catabolism, in two breeds of horses, Thoroughbred and Jeju, at different time intervals. The concentrations of metabolites in muscle and plasma were measured by 1H NMR (nuclear magnetic resonance) spectroscopy, and the relative metabolite levels before and after exercise in the two samples were compared. Subsequently, multivariate data analysis based on the metabolic profiles was performed using orthogonal partial least square discriminant analysis (OPLS-DA), and variable important plots and t-test were used for basic statistical analysis. The stress-induced expression patterns of BCKDK genes in horse muscle-derived cells were examined using quantitative reverse transcription polymerase chain reaction (qPCR) to gain insight into the role of transcript in response to exercise stress. In this study, we found higher concentrations of aspartate, leucine, isoleucine, and lysine in the skeletal muscle of Jeju horses than in Thoroughbred horses. In plasma, compared with Jeju horses, Thoroughbred horses had higher levels of alanine and methionine before exercise; whereas post-exercise, lysine levels were increased. Gene expression analysis revealed a decreased expression level of BCKDK in the post-exercise period in Thoroughbred horses.

Objective: In this study, we examined the effects of Kaltenborn-Evjenth concept-based cervical specific stabilization exercise (KESS) on pain, range of motion (ROM), pulmonary function, and functional ability in patients with chronic neck pain. Design: Randomized Controlled Trial. Methods: Thirty participants were randomly assigned to either a KESS (n = 15) or eye cervical re-education (ECRE) (n = 15) group. Both programs involved 5- to 10-second contractions per repetition, with 10 repetitions per set and three sets at 1-minintervals, performed three times weekly for 4 weeks. Data for within-group pre- and post-intervention comparisons and between-group differences were analyzed using paired and independent t-tests, respectively. The outcome measures included the visual analogue scale for pain, neck disability index (NDI) for functional disability, forced expiratory volume in 1 second for pulmonary function, cranio-cervical flexor test (CCFT) for deep neck flexor strength, proprioception tests, and cervical ROM measurements. Results: In both groups, we observed significant improvement in pain and NDI values, although with greater reductions in the KESS group participants. Whereas pulmonary function improved among participants in both groups, there were no significant between-group differences. Similarly, there were significant improvements in CCFT in both groups, although with the responses be more pronounced in KESS participants. Participants in both groups also showed significant improvements with respect to proprioception, although with limited differences in direction ratios. Moreover, in each group, there was a significant increase in ROM. Conclusions: Participants in the KESS group were found to show superior improvements with respect to pain, NDI, and deep neck flexor function, thus indicating that by targeting cervical segment stabilization, this exercise is more effective for the management of chronic neck dysfunction. However, the small sample size and lack of assessor blinding limits the interpretation of these findings.

Background: In patients with lumbar spinal stenosis (LSS), lumbar flexion exercise (LFE) is considered a standard therapeutic exercise that widens the space between the spinal canal and intervertebral foramen. However, some researchers have reported that lumbar extension exercise (LEE) may improve lumbar pain and functional ability in patients with LSS. Although exercise intervention methods for patients with LSS have been widely applied in clinical settings, few studies have conducted comparative analysis of these exercise methods. Objects: This study aimed to compare the effects of LFE, LEE, and lumbar flexion combined with lumbar flexion-extension exercise (LFEE) on pain, range of motion (ROM), pelvic tilt angle, and functional gait ability in patients with LSS. Methods: A total of 30 patients with LSS, LFE (n1=10), LEE (n2=10), and LFEE (n3=10) were assigned to each of the three exercise groups. The numerical pain rating scale (NPRS), modified-modified schober test (MMST)-flexion, MMST-extension, pelvic tilt inclinometer, and 6-minute walking test (6MWT) were measured. Results: After the intervention, statistically significant differences were observed in the NPRS (p=.043), MMST-flexion (p<.001), MMST-extension (p<.001), and 6MWT (p=.005) between groups. According to the post hoc test, the NPRS was statistically significant difference between the LFEE and LEE groups (p=.034). The MMST-flexion was statistically significantly different between the LFE and LEE (p=.000), LFE and LFEE (p=.001), and LEE and LFEE (p=.001) groups. The MMST-extension was statistically significantly different between the LFE and LEE (p<.001), LFE and LFEE (p=.002), and LEE and LFEE (p=.008) groups. The 6MWT was statistically significantly different between the LFE and LFEE (p=.042) and the LEE and LFEE (p=.004) groups. Conclusion: This study suggested that LFEE was the most effective exercise for pain and functional gait ability in patients with LSS, LFE was the most effective exercise for lumbar flexion ROM, and LEE was the most effective exercise for lumbar extension ROM.

Six-min walk test (6MWT) is widely used exercise test for the evalua-tion of interstitial lung disease (ILD). However, the long test duration and need for long and flat surface hinder its routine use. One-min sit-to-stand test (1-STST) is devoid of such limitations, but has been scarcely evaluated. The study was conducted to evaluate the performance of 1-STST by correlating it with 6MWT in ILD patients. Stable ILD patients were prospectively enrolled. After initial spirometry, all patients per-formed 6MWT and 1-STST following the standard recommendations. Exercise capacity and physiological parameters (heart rate, pulse oxy-gen saturation, blood pressure and dyspnea [modified Borg scale]) in-cluding peripheral oxygen saturation (SpO2) were correlated after the tests using Pearson correlation, Intraclass correlation coefficient (ICC) and kappa (κ) coefficient. The results showed that the mean age of the patients (n=60) was 58.8±11.5 years (male:female=1:1). Repetitions af-ter 1-STST showed significant correlation with 6MWT (r=0.48; P<0.001). Changes in the physiological variables were similar (P>0.05) with good consistency (ICC=0.68–0.95) between 6MWT and 1-STST. Both lowest SpO2 and difference in SpO2 also showed good agreement (ICC=0.86; 95% confidence interval [CI], 0.77–0.92 and ICC=0.68; 95% CI, 0.47–0.81 respectively) and significant correlation (r=0.76 and r=0.52, respectively). 1-STST and 6MWT were consistent in identifying patients having oxygen desaturation ≥4% (κ=0.56; 96% CI, 0.30–0.82). The results demonstrated that the performance of 1-STST was consis-tent with 6MWT in terms of exercise capacity and change in physiolog-ical parameters. 1-STST can be a valid alternative to 6MWT in the as-sessment of ILD patients, especially in peripheral health centers.