년 - 년
[Kisti 연계] 한국태양에너지학회 한국태양에너지학회 논문집 Vol.32 No.3 2012 pp.129-137
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This thesis introduced an azimuth tracking prismatic daylighting system. The system improved several issues of the previous passive prismatic daylighting system: low efficiency at sunrise and sunset, glare effect and polarized. The system was developed to track the movement of sun with azimuth tracking device, and it has its own power from the attached solar cells. We compared the with previous passive one in terms with system efficiency and daylighting factors(DF).
자연재해 및 방사능 오염 모니터링용 USN 식물공장관리방법 및 시스템 개발
[Kisti 연계] 한국방사선학회 한국방사선학회 논문지 Vol.5 No.6 2011 pp.351-355
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본 논문은 재난재해와 방사선 오염으로부터 안전한 농작물 관리를 위한 플랫폼, 그리고 식물 생장 모니터링 시스템을 제안하였다. 또한, 식물생장을 모니터링하여 식물공장 내에서 생장하는 식물의 크기를 효율적으로 측정할 수 있는 시스템을 개발하였다. 본 연구에 따른 기대효과는 첫째, 자연재해와 방사능오염 감시를 통해 신속하고 정확한 대처 기능으로 농산물 품질과 생산성 향상을 가져올 수 있다. 둘째, 식물의 크기 측정 데이터를 유지 관리하는데 소요되는 시간을 절약하여 경비를 절감할 수 있다. 마지막으로 식물 공장 관리자의 작업 효율을 향상시킬 수 있다.
In this paper, monitoring system and platform of plant growth are suggested which are required by safe crop management about disaster and radiation pollution. In addition, by monitoring plant growth, the growth of plants that can measure the size of the efficient system was developed. The expected effect of this study, first, through natural disasters and radioactive contamination monitors produce fast and accurate response function can result in improved quality and productivity. Second, the size of the plant required to maintain the measurement data can save time and expense savings. Finally, plant managers can improve work efficiency.
병원내 온도와 습도조절을 위한 태양광 발전 시스템 설계
[Kisti 연계] 한국방사선학회 한국방사선학회 논문지 Vol.5 No.3 2011 pp.127-134
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본 논문에서는 온도와 습도 및 냉 난방을 조절하여 건물 내의 쾌적한 환경을 제공하기 위한 승압쵸퍼와 PWM 전압형 인버터로 구성된 태양광 발전 시스템을 제안하였다. 이 시스템은 안정된 변조를 위해 원칩 마이크로프로세서를 사용하여 동기신호와 제어신호로 처리하였다. PWM 전압형 인버터와 위상의 동기를 위하여 계통전압을 검출하여 계통전압과 인버터 출력을 동상 운전하므로 잉여전력을 연계할 수 있게 하였으며, 건물이나 병원 등 특정 건물의 온도 및 습도센서에 적용하여 양호한 동특성을 얻을 수 있었다. 또한 시스템에 적용한 결과 고역률과 저고조파 출력을 유지함으로써 부하와 계통에 전력이 안정하게 공급될 수 있도록 제어하여 좋은 결과를 얻을 수 있었다.
In this paper we propose an improved PV generation systems. Improved systems for temperature and humidity controlled heating and air conditioning offers a pleasant environment within the building, set up chopper and consists of a PWM voltage type inverter. The proposed system is stable modulation for a one-chip microprocessor using the synchronous signal and control signals was treated. The proposed system is a PWM voltage type inverter and phase of the synchronous to the grid voltage to detect the system voltage and inverter output to drive the statue, so surplus power to connection was able to, certain buildings such as buildings or hospitals, temperature and humidity sensor is applied to the good dynamic characteristic could be obtained. In addition, the system was applied to the high power factor and low-frequency harmonics by maintaining the output load and grid to power to be supplied to a stable control could get a good result.
X-Ray 진찰용 고전압 공진형 DC-DC 컨버터 설계
[Kisti 연계] 한국방사선학회 한국방사선학회 논문지 Vol.4 No.4 2010 pp.11-16
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본 논문은 공진형 인버터로 구성된 X-ray 고전압 발생기와 고주파 고전압 변압기의 운영 시스템을 제안하였다. X선 발생장치는 무소음화와 소형화하였으며, 50[kHz]이상의 구동 주파수로 동작하게 하였고, 일반전원을 사용할 때 발생한 전력으로 인한 노이즈, 조사조건의 저하문제 등의 문제점을 해소하였다. 또한, X선관 전압 제어기와 관전류 제어기 및 고주파 고전압 변압기의 필라멘트 가열용 변압기를 고주파용으로 설계, 제작함으로써 X선 장치의 효율적 운영이 되도록 하였다.
In this paper, including the X-ray high voltage resonant inverter generators and high frequency high voltage transformer operating systems is proposed. X-ray generator removes the noise and was smaller, 50[kHz] to work more with the driving frequencies, and that occurred when the normal power supply available due to noise, survey the conditions and solve the problems of the poor was a problem. In addition, X-ray tube voltage, frequency controllers and tube current controller filament heating voltage transformer for high frequency transformer design and manufacture of doing X-ray devices were to become more efficient operation.
[Kisti 연계] 한국산학기술학회 한국산학기술학회 학술대회논문집 2010 pp.370-373
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본 논문에서는 유도전동기와 제어기의 폐루프 극점을 원하는 위치에 배치하여 유도전동기를 위한 PID제어 동조파라미터를 얻어 유도전동기를 제어하는 방법을 제안한다. 이러한 설계방법은, 설계요건뿐만 아니라 제어기 고유의 안정도와 강인성까지 제공하므로 매우 유용하다.
[Kisti 연계] 대한전기학회 전기학회논문지. The Transactions of the Korean Institute of Electrical Engineers. P Vol.59 No.4 2010 pp.345-350
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This paper presents a Photovoltaic Generation system using a Space Vector Modulation. PWM voltage source inverter using inverter consists of complex type of electric power converter to compensate for the defect, that is solar cell cannot be developed continuously by connecting with the source of electric power for ordinary use. It can cause the effect of saving electric power, from 10 to 20[%]. Synchronous signal and control signal was processed by the 56F8323 microprocessor for stable modulation. Also, Waveforms output current and voltage of system controlled so that phase conforms and can supply electric power that stabilize by the unit power factor.
공간벡터 PWM 방식을 이용한 태양광 발전 시스템 제어
[Kisti 연계] 한국방사선학회 한국방사선학회 논문지 Vol.4 No.3 2010 pp.31-37
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본 논문에서는 태양광 발전시스템을 이용한 PWM(Pulse Width Modulation) 전압형 인버터를 전력변환기로 구성하였고, 안정된 변조를 위해서 동기신호와 제어신호를 56F8323 마이크로프로세서에 의해서 처리하였다. PWM 전압형 인버터는 태양전지가 연속 발전할 수 없는 단점을 보완하기 위해 일반 상용전원과 연계함으로써 약 10~20[%]의 전력 절감 효과를 얻을 수 있는 에너지 절약 전원 복합형 전력변환장치로 구성하였다. 그리고 PWM 전압형 인버터와 위상동기를 위해서 계통전압을 검출하고 계통전압과 인버터 출력을 동상 운전하므로 잉여전력을 계통과 연계할 수 있게 하였다. 또한, 고조파를 절감한 출력을 유지함으로써 부하와 계통에 전력이 안정하게 공급될 수 있도록 제어 시스템을 적용하여 좋은 결과를 얻을 수 있었다.
In this paper, a photovoltaic system is designed with PWM(Pulse Width Modulation) voltage source inverter. Proposed synchronous signal and control signal was processed by 56F8323 microprocessor for stable modulation. The PWM voltage source inverter using inverter consists of complex type of electric power converter to compensate for the defect, that is solar cell cannot be developed continuously by connecting with the source of electric power for ordinary use. It can cause the effect of saving electric power, from 10 to 20[%]. The PWM voltage source inverter operates in situation that its output voltage is in same phase with the utility voltage. In addition, I connected extra power to the system through operation the system voltage and inverter power in a synchronized way by extracting the system voltage so that the phase of the system and PWM voltage inverter can be synchronized. In the system of this research showed good results after being controlled in order to provide stable power to the load and the system through maintaining and low output power of harmonics.
[Kisti 연계] 한국산학기술학회 한국산학기술학회 학술대회논문집 2010 pp.366-369
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본 논문에서는 가상현실 고소공포증 치료를 위한 원격진료 시스템을 제안하였다. 제작된 가상현실 시뮬레이터를 원격진료시스템에 연결시켜 원격지에서 PC를 통하여 작동시킴으로써 고소공포증 치료를 시도할 수 있도록 하였으며, 전문의가 환자 상태를 체크할 수 있도록 생체 신호를 전문의에게 전송하고 질문지를 온라인상으로 답변할 수 있는 시스템을 적용하였다.
만성두통 환자에서 한방 치료 후 인영혈 부위의 뇌혈류에 대한 연구
[Kisti 연계] 대한한방신경정신과학회 동의신경정신과학회지 Vol.20 No.1 2009 pp.199-214
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Objectives : This study was performed to change of blood flow in In-Young(ST9) after treatment on chronic daily headache patients. Methods : Monitoring of TCD was examined in 10' s chronic daily headache patients before and after treatment. Mean velocity flow, systolic velocity and pulsatility index were analyzed from TCD at In-Young(ST9). The patients was laid for 20 minutes before treatment and also for treatment. Results : The results showed a significant(p<0.05: Paired T-test) decrease in mean velocity flow and systolic velocity. but there were no significant differences in pulsatility index. Conclusions : These results suggest that there were significant change on blood flow in In-young of chronic daily headache patients.
[Kisti 연계] 한국태양에너지학회 한국태양에너지학회 학술대회논문집 2009 pp.37-42
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We are in search for many method at 21th century thinking about the environment internationally. One is among them low carbon green city. Consequently this dissertation put a system solar energy key point of low carbon green city and purpose of low carbon green city Besides system and technique about the solar energy best practices try to do the investigation analysis. It's important of low carbon green city's environmental friendly system such as solar heat system, solar power generation, ecological greening, All these systems are connected each other and organize low carbon green city. A solar energy system uses pure energy of the situation directly most among the environmental friendly system. Energy saving and environment-friendly city in the world must do not a choice. However, recognition conversion and infrastructure of the Korea still has not come true. But South Korea and the international best practices is not the same system. But plan to solar city, the concept of green city in Cheongju, Deagu local government. And many meetings are in progress.
[Kisti 연계] 대한전기학회 대한전기학회 학술대회논문집 2009 pp.957-958
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2DOF is applied to induction moor in order to supply these weak points of PI speed control method in this paper. and proposed method utilize the combination of the voltage model based on stator equivalent model and the current model based on rotor equivalent model, which enables stable estimation of rotor flux. And it also emphasizes the improvement of the control characteristics in low speed region where established schemes have many problems. To prove the propriety of this paper, the various simulations carried out adequacy and stability using Matlab, and at the same time real system is made, so it is proved. As the results of embodying the system, the robust system is realized.
BIPV 시스템에서의 모듈 종류에 따른 건축적 특성 연구 - 채광형 시스템을 중심으로 -
[Kisti 연계] 한국태양에너지학회 한국태양에너지학회 학술대회논문집 2008 pp.196-202
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Effective climate protection is a most important tasks of our time. The BIPV is one of the most interesting and promisingly possibilities of an active use of solar energy at the building. In this study it was analyzed by the case study the function of the requirement of the BIPV-module as building material and this architectural characteristic according to the kind of the module. Therefore the goal of this study is to get securing the application information of BIPV as windowpane. BIPV modules are manufactured in the form of G/G. In the case of the crystal type the Transparent and the light Transmission is to be adjusted by the spacer attitude of the cell. Although this type could not be optimal for light effect of indoors because of the inequality of shade, the moving shade play makes a dramatic Roomimage by the run of sun. The application of this type would be for canopy, window or roof in the corridor or resounds. With amorphous the type it is to be manufactured simply largely laminar, and thus that will shorten building process. There is a relatively good economy to use and to the window system easily. After the production technology is easy the transparency of the modules to adjust, and the module shows to a high degree constant characteristics of light permeability and transparency. Without mottle of module shade is good the use for the window or roof glazing of office, library, classroom, etc. to adapt. The BIPV modules took generally speaking a function as building material to the daylight use, shading, isolation and also to the sight. That means that BIPV modules have as multifunctional system to sustainable architecture good successes and they are at the same time as Design element for architecture effectively.
[Kisti 연계] 대한한방신경정신과학회 동의신경정신과학회지 Vol.19 No.3 2008 pp.195-203
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Objective: 'GyoGam-Dan' is known as a medicine to cure depression in Donguibogam (traditional Korean oriental medicine book). GyoGam-dan which is composed of Cyperi Rhizoma L. and Poria cum Radix pini has been used by basic prescription of asymptom related to all kinds of Qi(氣) disease. Although it has been clinically used for a long time, its safety have never been proved till now. Methods: We had collected data of 610 cases of patients taking 'GyoGam-Dan' at Wonkwang univ. oriental medical center for a period of three years (2005.3.09-2008.04.30). On the patients' blood, the levels of LFT and RFT were examined and the residual levels of heavy metals and pesticides were measured. Results: There were 610 patients who had taken GyoGam-Dan for about three years. In the patients, the most common diseases is depression, followed by palpitation, and then insomnia. Among the patients' estimations on its effectiveness, there were many of positive ones. The blood analyses of patients who had taken GyoGam-Dan did not show any problems and moreover there was not any problems in the levels of residual heavy metals and agricultural pesticides. Taken together, GyoGam-Dan was proved to be a safe medicine for health. Conclusions: Our clinical and chemical studies show that GyoGam-dan has the anti-stress effect and is a safe medicine of which side effect does not exist. Hereafter, Nigorous clinical trial on GyoGam-dan is required.
[Kisti 연계] 대한전기학회 대한전기학회 학술대회논문집 2008 pp.1184-1185
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The wind generation system is trend that amount used increases recently. In this paper, Introduce about development of wind force development system. This system does easily research for wind power. Compose a control program by VB so that alteration, output result deposit and waveform analysis etc. is possible and did so that all manufacturing and checkout may be available in computer.
BIPV 시스템의 차양 효과에 따른 피크 냉방부하 절감효과에 관한 연구
[Kisti 연계] 한국태양에너지학회 한국태양에너지학회 논문집 Vol.28 No.5 2008 pp.14-20
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As the number of buildings that use the transparent permeation materials as the outer wall is on the increase, the coming amount of the light rays is a lot, and thus the increase in the cooling load and the radiant heat of high temperature may cause the residents to discomfort. In order to reduce such influences, this paper analyzed the installation effects of the sunshade BIPV. The inner temperature of the room installed the sunshade BIPV or otherwise was measured, and compared and analyzed the effects of reducing the cooling load by the incoming light rays. The sample space of the third floor of S university installed the sunshade BIPV has two rooms on the same conditions, and for five sunny days selected in August, the researcher measured the air temperature and the temperature of the fittings with closing the windows to minimize the movement of air without operating the coolers. The maximum cooling load measured by the incoming light rays in the room where the sunshade BIPV was not installed was examined as 459.13kcal/h. It can be understood as the effect of reducing the cooling load according to the incoming rays of the room with sunshade BIPV. Even though the effect of cooling load reduction is not so great in a room, the total reduction in cooling room for the 32 rooms installed the sunshade BIPV was estimated to be 40442.27kcal/day, which will be able to bring the maximum reduction effect of 17.1kW in energy and reduce the investment cost owing to the reduction in cooling load when initially designing the building.
[Kisti 연계] 대한전기학회 대한전기학회 학술대회논문집 2007 pp.1224-1226
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전압형 인버터에 의해 제어되며 인버터의 스위칭 게이트 신호 발생은 전압변조가 필요하다. 전압변조는 삼각파 비교 PWM, 공간전압벡터(Space voltage Vector) PWM기법 등으로 실현되고 있으나, SVPWM은 타 방식에 비해 고조파의 왜형률을 감소시키고, 디지털 구현이 용이하며 선형제어 영역을 증가시킬 수 있는 장점이 있다. 따라서 본 논문에서는 먼저 SVPWM의 스위칭 이론 및 각 섹터에 따른 방향에 대해 설명하였고, 태양광발전 시스템을 3상 PWM전압형 인버터로 구성하였고 안정된 변조를 위해서 동기신호와 제어신호를 위해 모토로라사의 56F8323 마이크로프로세서에 의해서 처리하였다. 또한 시스템의 출력전압과 전류의 파형은 전원전압과 출력전류가 위상이 일치되어 단위 역률로 안정된 전력을 공급할 수 있도록 제어하였다.
합곡(合谷) 및 족삼이(足三里) 혈(穴) 자침이 인영혈(人迎穴)부위의 뇌혈류에 미치는 영향
[Kisti 연계] 대한한방신경정신과학회 동의신경정신과학회지 Vol.18 No.1 2007 pp.143-151
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Objective : This study was performed to evaluate the effects of Hap-Kok(LI4) and Jok-Sam-Lee(ST36) acupuncture on blood flow in In-Young(ST9). Method : Monitoring of TCD was examined in each 25's healthy men and wemen in 20s before and after acupucture on both(right and left) Hap-kok(LI4) and was done on both(right and left) Jok-Sam-Lee(ST36) by different group with same condition. Mean velocity and Pulsatility index analyzed from TCD at both In-Young(ST9). Both group was acupuctured for 15-20 minutes laying at bed. Results : The results showed a significant($p{\le}0.05:$ Paired T-test) decrease in mean velocity and increase in pulsatility index at both group. Conclusion : These results suggest that acupuncture could have a specific effect on blood flow called In-Young acupoint.
유제한성 병기의 소세포 폐암에서 3주 간격으로 시행된 irinotecan과 cisplatin을 이용한 과다분할 방사선 동시 요법
[Kisti 연계] 대한결핵및호흡기학회 Tuberculosis and respiratory diseases Vol.63 No.2 2007 pp.154-164
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배경: Irinotecan hydrochloride는 topoisomerase I inhibitor로서 소세포 폐암에 효과적인 약제로 알려져 있다. Irinotecan은 cisplatin과 더불어 방사선감작물질로 작용하기도 한다. 본 연구는 이전에 치료받은 경험이 없는 제한성 병기의 소세포 폐암 환자에서 irinotecan과 cisplatin(IP)의 방사선 동시화학요법의 효과를 평가하기 위하여 시행되었다. 방법: 2002년 12월부터 2004년 11월까지 충남대학교 병원에서 새로이 제한성 병기의 소세포 폐암으로 진단된 24명의 환자들을 대상으로 하였다. Irinotecan $60mg/m^2$을 제 1일과 제 8일째 투여하였고 cisplatin $60mg/m^2$을 제 1일째 투여하였으며 매 3주 간격으로 시행되었다. 제 3차 항암화학요법을 시작하는 날과 동시에 과다 분할방사선 치료(twice-daily thoracic irradiation; 45 Gy total)을 시작하였다. 예방적 전 뇌 방사선 조사(Prophylactic cranial irradiation)가 방사선 동시화학요법이 끝난 후 완전반응(complete response)을 나타낸 환자에서 시행되었다. 제 2차 항암요법과 제 6차 항암요법이 끝난 후에 흉부 전산화 단층촬영과 기관지경 등을 통한 병기의 재평가가 이루어졌다. 결과: 병기의 재평가는 19명의 환자에게 이루어졌다. 중앙 추적관찰기간은 12.5개월이고 전체 99회의 항암치료가 시행되었다. 평균 한 환자당 5.2회의 항암치료가 시행되었다. 실제 용량강도는 cisplatin $19.6mg/m^2$/week과 irinotecan $38.2mg/m^2$/week이었다. 9명의 환자가 완전반응을 보였고 10명의 환자가 부분반응(partial response)을 보여서 전체 반응률은 95%였다. 3에서 4도의 혈액학적 독성은 백혈구 감소증(35% of cycles), 빈혈(7% of cycles), 혈소판 감소증(7% of cycles) 등으로 나타났다. 3에서 4도의 비 혈액학적 독성은 설사(5% of cycles)였다. 3에서 4도의 방사선 식도염(10% of patients)을 제외하고는 과다 분할 방사선 치료를 이용한 방사선 동시 화학요법의 기존의 방법과 독성 면에서는 큰 차이가 없었다. 치료와 관련된 사망은 관찰되지 않았다. 평가가 가능한 환자들에서 1년 생존율과 2년 생존율은 각각 89% (16/18)와 47% (9/18)였다. 결론: 3주 간격으로 시행된 irinotecan과 cisplatin을 이용한 과다분할 방사선 동시 요법은 제한성 병기의 소세포 폐암 환자에서 부작용은 높지 않으면서 효과적인 치료법으로 고려될 수 있을 것이다.
Background: Irinotecan hydrochloride, a topoisomerase I inhibitor, is effective against small-cell lung cancer. Irinotecan also can act as a potential radiation sensitizer along with cisplatin. To evaluate efficacy and toxicity of irinotecan plus cisplatin (IP) with concurrent thoracic radiotherapy, we conducted a phase II study of IP followed by concurrent IP plus hyperfractionated thoracic radiotherapy in patients with previously untreated limited-stage small-cell lung cancer. Methods: Twenty-four patients with previously untreated small-cell lung cancer were enrolled onto the study since November 2004. Irinotecan $60mg/m^2$ was administered intravenously on days 1 and 8 in combination with cisplatin $60mg/m^2$ on day1 every 21 days. From the first day of third cycle, twice-daily thoracic irradiation (total 45 Gy) was given. Prophylactic cranial irradiation was given to the patients who showed complete remission after concurrent chemoradiotherapy. Restaging was done after second and sixth cycle with chest CT and/or bronchosocpy. Results: Up to November 2004, 19 patients were assessable. The median follow-up time was 12.5 months. A total of 99 cycles (median 5.2 cycles per patient) were administered. The actual dose intensity values were cisplatin $19.6mg/m^2$/week and irinotecan $38.2mg/m^2$/week. Among the 19 patients, the objective response rate was 95% (19 patients), with 9 patients (47%) having a complete response (CR). The major grade 3/4 hematological toxicities were neutropenia (35% of cycles), anemia (7% of cycles), thrombocytopenia (7% of cycles). Febrile neutropenia was 4% of cycles. The predominant grade 3/4 non-hematological toxicities was diarrhea (5% of cycles). Toxicities was not significantly different with concurrent administration of irinotecan and cisplatin with radiotherapy, except grade 3/4 radiation esophagitis (10% of patients). No treatment-related deaths were observed. The 1-year and 2-year survival rate of eligible patients was 89% (16/18) and 47% (9/18), respectively. Conclusion: Three-week schedule of irinotecan plus cisplatin followed by concurrent IP plus hyperfractionated thoracic radiotherapy is an effective treatment for limited disease small-cell lung cancer, with acceptable toxicity.
모델 기준 적응 시스템(MRAS) 부하 토크 관측기를 이용한 유도 전동기의 속도 제어
[Kisti 연계] 한국신호처리시스템학회 한국신호처리.시스템학회 논문지 Vol.8 No.2 2007 pp.119-123
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본 논문은 유도전동기의 센서리스 속도제어기에 대한 연구이다. 유도전동기의 속도의 제어방법은 자속추정을 위한 기준모델로써 부하-토크 관측기를 이용한 MRAS(Model Reference Adaptive System)를 기초로 하였으며, 전형적인 MRAS 제어기 특성의 속도응답은 부하 토크 외란의 변화에 영향을 미친다. 따라서 제안된 시스템에서의 부하-토크 관측기를 사용한 속도제어 특성은 부하 토크 외란에 의한 영향을 받지 않는다. 이러한 제어 알고리즘을 MATLAB의 SIMULINK를 통해 전체 시스템을 모델링하여 시뮬레이션 한 결과는 유도 전동기의 다양한 부하 구동 적용에 대한 슬라이딩 속도 제어기의 효과적인 개선이 되었음을 알 수 있었다. 그러므로 이러한 제어 방법들이 산업 응용분야에 확대되어 적용되었으면 한다.
This paper investigates a speed sensorless control of induction motor. The control strategy is based on MRAS(Model Reference Adaptive System) using load-torque observer as a reference model for flux estimation. The speed response of conventional MRAS controller characteristics is affected by variations of load torque disturbance. In the proposed system, the speed control characteristics using a load-torque observer control isn't affected by a load torque disturbance. Control algorithm that propose whole system through MATLAB SIMULINK because do modelling simulation result are presented to prove the effectiveness of the adaptive sliding mode controller for the drive variable load of induction motor. Therefore we hope to be extended in industrial application.
[Kisti 연계] 대한한방신경정신과학회 동의신경정신과학회지 Vol.18 No.1 2007 pp.153-171
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Objective : The aim of this study was to investigate effects of Gagambosim-Tang(GBT) of focal brain ischemic injury induced by intraluminal filament insertion in the rats. Method : The ischemia was induced by intraluminal filament insertion into middle cerebral artery Eight-arm radial maze was designed for the behavioral task. Gagambosim-Tang was orally administrated in SD rats for 21 days. The task was started on the 4th week after focal brain injury, and performed two trials per day for 6days. The effects of Gagambosim-Tang on neuroprotective agents in cresyl violet, choline acetyltranferase(ChAT), nerve growth factor (NGF)-stain and c-Fos with ischemic injury were investigated. Results : The errors in the eight-arm radial maze task were significantly decreased in normal group compared with control group on 2-6days, GBT lX(42.2 mg/ml)orally administrated group on 1days, GBT 6X(253.2 mg/ml) on 3, 5, 6days. The rate of correct choice was increased in normal and GBT 6X groups. The neuroprotective effect in the hippocampal CA1 was increased in normal and GBT 1X, GBT 6X groups compared with control group. The density of ChAT in the hippocampal CA1 was increased in normal and GBT6X groups compared with control group. The density of NGF in the hippocampal CA1 was increased normal and GBT6X groups compared with control group. The number of c-Fos-positive neurons in the hippocampal CA1 was increased in normal and GBT 6X groups compared with control group. Conclusion : These results suggest that Gagambosim-Tang may have protective effect on dementia.
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