Chi Hoa Pham, Jung-Eui Hong, Byoung-In Sang, Man-Bock Gu
언어
영어(ENG)
URL
https://www.earticle.net/Article/A99981
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Up to date, Silver nanopartilces (NPs) are the second largest products after carbon NP (Nanotubes & Fullerenes). There are many potential benefits of nanotechnology, but its hazards and risks are poorly understood. We have conducted an isolation of ESTs from male medaka liver and characterized unique 575 cDNAs cloned after sequencing and redundancy check of more than 2000 cDNAs obtained in randomly generated ESTs. Gene expression analysis with 575 cDNAs from specific tissues (gill, intestine, liver) were performed in exposure of Silver NPs (20 nm) to medaka using DNA microarray. A high dose (25 ppb) and a low dose (1 ppb) of the NPs were tested at various exposure time points. As the results, whether the NPs were uptake into the fish through gill or/and intestine they were accumulated in livers as the highest numbers of genes up or down regulated at any time point. For further understanding toxic mode causing by Silver NPs, its expression profile was compared to profiles of Gold colloid and Silver nitrate exposed to medaka. This study gives us additional knowledge of the environmental and ecological implications associated with nanotechnology.
저자
Chi Hoa Pham [ School of Life Science & Biotechnology, Korea University ]
Jung-Eui Hong [ School of Life Science & Biotechnology, Korea University ]
Byoung-In Sang [ Center for Environmental Technology Research, Korea Institure of Science and Technology ]
Man-Bock Gu [ School of Life Science & Biotechnology, Korea University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동