Earticle

초록

영어

Recently, surface plasmons of noble metallic materials (typically gold and silver) have been received much attention due to the phenomena are the bases of many standard tools for measuring adsorption of material onto planar metal surfaces (surface plasmon resonance (SPR)-based biosensors) or onto the surface of nanometer-sized metallic structures (localized surface plasmon resonance (LSPR)-based biosensors). For the planar surfaces, the SPR reflectivity measurements can be used to detect DNA, proteins or microorganisms by the changes in the local index of refraction upon adsorption of the target molecules to the metal surfaces. For the nanometer-sized particles, localized surface plasmon oscillations can give rise to the intense colors of solutions of plasmon resonance nanoparticles and/or very intense scattering. Nanoparticles of noble metals exhibit strong UV-Vis absorption bands that are not present in the bulk metal. Shifts in this resonance due to changes in the local index of refraction upon adsorption of target biomaterials to the nanoparticles can also be used to detect analytes such as DNA, proteins or other small molecules. In light of the useful and unique surface plasmon polaritons, many SPR-based biosensing platforms have been successfully carried out for detections of biomarker proteins and microbial spores in our lab. Moreover, LSPR of gold nanoparticles has also been being exploited to develop colorimetric biosensors and nanosensors for antigen-antibody biosensings. The strategy has several advantages, such as: non-invasive and non-labeling detection, high sensitivity, fast detection possibility, etc. More details will be thoroughly described in the presentation.

저자

• Cuong Cao [ Department of Chemical Engineering, Sungkyunkwan University ]
• Sang Jun Sim [ Department of Chemical Engineering, Sungkyunkwan University ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576