In modern science and technology, size matters, because materials exhibit new characteristics in nano scale, which do not exist in bulky state. Scientists have made great efforts to utilize the distinctive properties of nano sized materials especially for overcoming drawbacks of conventional sensors. Quantum dots are one of representing labeling nanoparticles which have photostability, size tunable color, broad exciting energy level and narrow emission spectrum. Other noticeable labeling agents are gold nanoparticles because of their high light absorbing efficiency. Therefore, I investigated the use of the strong optical signaling nanoparticles as labeling agents for novel nanoscale materials such as DNA, proteins and carbon nanotubes. In particular, the nanoparticles were applied to develop simple homogenous assay modes. For these purposes, FRET was implied to both quantum dots and gold nanoparticles. FRET is controllable by engineering the interaction between targets and probe molecules. Molecular beacon and isothermal cycling probe technology were applied to engineering FRET on the nanoparticles for target specific signaling. Accordingly, I will presents the target detecting functions of the labeling nanoparticles and discuss functional effecting factors.
저자
Joong Hyun KIM [ Dept. of Chemistry, Pohang University of Science and Technology. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동