Hee-Woon Kim, Keun Woon Choi, Jung Kwon Lee, Hee-Guk Byun
언어
영어(ENG)
URL
https://www.earticle.net/Article/A99437
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Chitooligosaccharides (COSs) are derivative of chitosan and it can be obtained by either enzymatic or chemical hydrolysis of chitosan. COSs are not only water-soluble but also possess versatile biological activities such as antitumor, immunostimulating, antioxidant and antimicrobial activity1). This study investigated antioxidative effects of carboxymethyl chitooligosaccharides (CM-COS) on the generation of direct free radical scavenging activity by using electron spin resonance (ESR) spectrometer and measure Fourier transform infrared (FT-IR) spectroscopy. Antioxidative activities of CM-COS at 70% and 80% were measured, respectively. And cytotoxic effect was measured by the method of Park et al1). In the results of ESR spectrometer, the CM-COS 80% had the highest antioxidant activity compared to the other CM-COS. The IC50 values of 80% CM-COS were 3.29, 6.25, 2.65 and 1.50 mg/ml for DPPH, hydroxly, superoxide, alkyl radical, respectively. Moreover, CM-COS did not show any cytotoxic effect against MRC-5 cell lines.
저자
Hee-Woon Kim [ Faculty of Marine Bioscience and Technology, Kangnung National University ]
Keun Woon Choi [ Faculty of Marine Bioscience and Technology, Kangnung National University ]
Jung Kwon Lee [ Faculty of Marine Bioscience and Technology, Kangnung National University ]
Hee-Guk Byun [ Faculty of Marine Bioscience and Technology, Kangnung National University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동