Hee Ho Park, Ju Hyun Park, Min Suk Kang, Jin Seok Park, Ji Woo Yeo, Tai Hyun Park
언어
영어(ENG)
URL
https://www.earticle.net/Article/A99436
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원문정보
초록
영어
In previous reports, anti-oxidant effect of deproteinised silkworm hemolymph (DSH) was confirmed by its ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals in in vitro experiments. In vivo level stamina enhancement activity of DSH, extracted from 5th instar larvae of Bombyx mori, was investigated on Sprague Dawley rats via a weight-loaded forced-swimming test using Pb as the weight. Oral administration of DSH at a concentration of 1.0 ml/kg body weight to rats was given daily for 7 and 14 days using sonde as the feeding apparatus. The rats had undergone 5 min/day swimming to accustom them to swimming. To limit the circadian variations, fasting, feeding and swimming times were consistent. After 7 and 14 days, final swimming times were assessed as the point of exhaustion by their inability to rise back to the surface for 7 seconds. Comparative results showed that 7 day and 14 day DSH administered group had a remarkable 34.7% and 4.2% increase in the swimming time than the 3 step filtered water group (control), respectively. From our findings, we have verified that stamina increases with respect to increase in the period of DSH intake which demonstrates the intake period dependency of DSH on stamina. The findings of this study indicate that DSH dosage of 1.0 ml/kg body weight has a significant stamina enhancing effect and opens the possibility as a potential energy beverage or usage as a therapeutic medicine.
키워드
deproteinised silkworm hemolymphin vivoratstaminaweight-loadedforced-swimming test
저자
Hee Ho Park [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
Ju Hyun Park [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
Min Suk Kang [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
Jin Seok Park [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
Ji Woo Yeo [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
Tai Hyun Park [ School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742, Korea ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동