Hyang-Hee Joo, Jae-Hyung Choi, Seoung-Min Jo, Mi-Ran Han, Jin-Chul Kim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A99360
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Two kinds of topical dosage forms of hinokitiol (HKL), namely vesicles and oil-in-water emulsions, were prepared. Behenyl trimethylammonium chloride and fatty acids were used as bilayer-forming materials of the vesicles, and oils were employed as oil phases of the emulsions. The substantivity of HKL in the preparations was evaluated in vitro using hairless mouse skins. After applying the preparations onto the skin and rinsing it, the amount of HKL left on the skin was determined using high performance liquid chromatography. It was higher when HKL was encapsulated in cationic vesicles rather than in non-ionic vehicles, emulsions. In vivo hairgrowth-promotion effect of each dosage form was investigated, where the sample application onto the clipped backs of female mice (C57BL6) and the subsequent rinsing of the backs were done once a day for 30days. Only HKL in the cationic vesicles had hair growth promotion effect, possibly due to the significant substantivity.
저자
Hyang-Hee Joo [ School of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University ]
Jae-Hyung Choi [ School of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University ]
Seoung-Min Jo [ School of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University ]
Mi-Ran Han [ School of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University ]
Jin-Chul Kim [ School of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동