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Fabrication of Nanocaved Surface and Immobilization of HeLa Cells for utilizing of Biochip

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2008 추계학술대회 및 국제심포지움 (2008.10)바로가기
  • 페이지
    pp.118-118
  • 저자
    Mi Jung, Waleed Ahmed El-Said, Byung-Keun Oh, Jeong-Woo Choi
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A99204

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원문정보

초록

영어
In recent years, the cell-based assay has been used for the detection of drugs, toxicants, and other cell functional characterization. For these cell-based assays, there is an increasing demand for more rapid and simple procedures for studying the cell viability and the effect of drugs on cell behavior. Immobilization of cell is very important process in the fabrication of cell chip since the performance is highly affected by the cells that are immobilized on substrate. HeLa cells have been used to study the effect of anticancer drugs on cells. In order to to enhance adhesion of HeLa Cells on surface, we fabricated nanoconcaved surface using nanoporous alumina. Uniform nanoconcaved patterns were revealed on surface of aluminum after the removal of nanoporous alumina formed during anodization. Au was deposited on nanoconcaved surface by sputtering. HeLa cells were immobilized on the Au nanoconcaved surface.
The results imply that gold-coated nanoconcaved surface can be utilized as nanobioplatform to construct biochip such as cell chip. Acknowledgement: This research was supported by the Nano/Bio science & Technology Program (M10536090001-05N3609-00110) of the Ministry of Education, Science and Technology (MEST), by the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korea government (MEST)(2006-05374) and by the Core Environmental Technology Development Project for Next Generation funded by the Ministry of
Environment of Korea.

저자

  • Mi Jung [ Interdisciplinary Program of Integrated Biotechnology ]
  • Waleed Ahmed El-Said [ Interdisciplinary Program of Integrated Biotechnology ]
  • Byung-Keun Oh [ Interdisciplinary Program of Integrated Biotechnology, Department of Chemical and Biomolecular Engineering, Sogang University ]
  • Jeong-Woo Choi [ Interdisciplinary Program of Integrated Biotechnology, Department of Chemical and Biomolecular Engineering, Sogang University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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    피인용수 : 0(자료제공 : 네이버학술정보)

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