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Anti-Aging and Whitening Activities of Labisia pumila Extract

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2008 추계학술대회 및 국제심포지움 (2008.10)바로가기
  • 페이지
    pp.8-8
  • 저자
    Hyun-kyung Choi, Myoungjin Oh, Dong-hyun Kim, Jin Wook Kim, Sulaiman Ngadiran, Mohamad Roji Sarmidi, Chang Seo Park
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A99045

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원문정보

초록

영어
Labisia pumila has been used for many generations by the Malay women as a post-partum medicine. The herb Kacip Fatima has long been regarded as the "queen" of Malaysian herbs. But its skin efficacy has not been studied yet. In this study, we have thus focused on finding anti-aging and anti-melanogenesis efficacy of the Labisia pumila extract. Extracts of Labisia pumila were analyzed for their antioxidant activities by DPPH (2,2-diphenyl-1-picrylhydrazyl) methods and found it has strong antioxidant activity. Treatment with the Labisia pumila extract enhanced collagen synthesis and inhibited the production of pro-inflammatory cytokines. Labisia
pumila extract protects cell damage induced by UVB. Collagen synthesis of human dermal fibroblasts treated with Labisia pumila is increased dose dependent manner. Labisia pumila extract showed the strongest anti-melanogenesis activity. Treatment with the Labisia extract inhibits α -melanocyte stimulating hormone induced melanin synthesis in B16F1 melanoma cells. However the Labisia extract did not inhibit mushroom tyrosinase activity in vitro. Instead internal tyrosinase activity was reduced significantly by the treatment of the Labisia extract, which suggested that Labisia extract suppressed the expression of tyrosinase gene. The results
show that the Labisia pumila extract has strong radical scavenging activity, anti-inflammatory activity and also restores collagen production by the UVB irradiated dermal cells. It also has strong inhibitory activity in melanogenesis. Taken together, the Labisia pumila extract has a good
potential as anti-aging and whitening agent for cosmetic ingredient.

저자

  • Hyun-kyung Choi [ Department of Chemical and Biochemical Engineering, Dongguk University ]
  • Myoungjin Oh [ Department of Chemical and Biochemical Engineering, Dongguk University ]
  • Dong-hyun Kim [ Department of Chemical and Biochemical Engineering, Dongguk University ]
  • Jin Wook Kim [ LSC Biotech, Seoul, Korea ]
  • Sulaiman Ngadiran [ Chemical & Natural Resources Engineering, Universiti Teknologi Malaysia ]
  • Mohamad Roji Sarmidi [ Chemical & Natural Resources Engineering, Universiti Teknologi Malaysia ]
  • Chang Seo Park [ Department of Chemical and Biochemical Engineering, Dongguk University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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