Skin wrinkles typically appear as a result of aging processes. Wrinkling in skin is caused by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors. Although wrinkle can signify wisdom, most people nowadays would rather not have them. Many products and procedures promise to reduce wrinkles. Some do little or nothing (like the products that claim they reduce "the appearance of fine lines," which means that they don't reduce the lines themselves). Others can achieve a fair amount of success. Jeju island is the most beautiful place in Korea. There are approximately 2000 plant species. We were tried to find new anti wrinkle agents derived from the plants. We found a few materials originated from the plants have got anti wrinkle effects in vitro and/or in vivo. Asiaticoside: A saponin component isolated from Centella asiatica, has been shown to induce type I collagen synthesis in human dermal fibroblast cells, We have been characterized the action mechanism of Asiaticoside in molecular level. We also evaluated the effects of a preparation containing asiaticoside on the periorbital wrinkles of a group of human volunteers. I this study, with 12 weeks of treatment with the Asiaticoside cream, most of the periorbital wrinkles were attenuated to some degree. Emodin: Matrix metalloproteinases(MMPs) are the proteases in the degradation of the extracellular matrix. In this study, we found that Emodin, an anthraquinone which has been isolated from the rhizome of Rheum palmatum, significantly inhibited TNFalpha-induced MMP-1 expression. These findings suggest that Emodin could be of therapeutic value in the prevention of MMP-1-related aging process containing wrinkle formation.
저자
Jongsung Lee [ BioSpectrum Life Science institute, Gunpo City, Gyunggi Do, Republic of Korea ]
Eunsun Jung [ BioSpectrum Life Science institute, Gunpo City, Gyunggi Do, Republic of Korea ]
Deokhoon Park [ BioSpectrum Life Science institute, Gunpo City, Gyunggi Do, Republic of Korea ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동