Yong Ho Noh, So Young Kim,, Se Kyung Kim, Jin Won Lee, Hyun Shik Yun
언어
영어(ENG)
URL
https://www.earticle.net/Article/A98980
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원문정보
초록
영어
1,2-Propanediol (1,2-PD, propylene glycol) is a chemical which has three carbon-diol and it contains a stereo structure at center of carbon. It is mostly used in unsaturated polyester resins, cosmetics, liquid detergents, detergents and solvent for unstable to water in pharmaceutical industry. Saccharomyces cerevisiae is a well known and a useful strain for industrial fermentation. Since S. cerevisae does not have genes necessary for the production of 1,2-propanediol, it is essential to import the genes from 1,2-propanediol producing cells. The objective of this research is to construct a plasmid for S. cerevisae to produce 1,2-propanediol by genetic manipulation. For this work, the key enzymes in the metabolic pathway of S. cerevisiae were selected for the production of 1,2-propanediol methylglyoxal synthase and glycerol dehydrogenase. Methylglyoxal synthase convert dihydroxyacetonephosphate (DHAP) to methylglyoxal. Glycerol dehydrogenase is involved in the conversion of glycerol to dihydroxyacetone. The genes which encode methylglyoxal synthase (mgs) and glycerol dehydrogenase (gldA) were obtained from Escherichia coli. The genes were cloned in a pESC-URA vector and transformed to S. cerevisiae.
저자
Yong Ho Noh [ Department of Biological Engineering, Inha University ]
So Young Kim, [ Department of Biological Engineering, Inha University ]
Se Kyung Kim [ Department of Biological Engineering, Inha University ]
Jin Won Lee [ Department of Chemical Biomolecular Engineering, Sogang University ]
Hyun Shik Yun [ Department of Biological Engineering, Inha University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동