Microalgae are photosynthetic organisms to produce industrially important metabolites such as astaxanthin, β-carotene, unsaturated fatty acid and phycobiliprotein etc. In order to enhance their productivity, researchers have developed many kinds of bioreactors and various cultivation methods. But recently these efforts came to limitation. Because of these reasons, systems biology started to attract researchers who want to increase productivity using novel tools or technology. Through the use of systems biology, researchers can model molecular and cellular phenomena of microalgae using integrated and interacting network of genes, proteins and biochemical reactions. In order to model levels of in silico behaviors, large volume of genome-scale data is required. The first step is to identify open reading frames and determine their biochemical reactions. After that, network gaps are determined by biochemical or physiological evidence. The accuracy of metabolic network can be analyzed by mathematical methods such as flux-balance analysis. Consequently comprehension of microalgae using systems biology is expected to increase their productivity as well as develop photosynthetic mechanism.
키워드
cyanobacteriasystems biologymetabolic reconstructionin silico model
저자
Seong-Joo Hong [ Department of Biological Engineering, Inha University ]
Choul-Gyun Lee [ Department of Biological Engineering, Inha University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동