Earticle

초록

영어

Coprinus cinereus peroxidase (CIP) is a kind of fungi peroxidase which catalyzes alkyl phenol compounds. It can catalyze the polymerization of ortho-, meta-, and para- phenol compounds. The phenol compounds are phenol, cresol, ethyl phenol, isopropyl phenol, and tert-butyl phenol. All meta- and para- phenol compounds are catalyzed by CIP but o-isopropyl phenol and o-tert-butyl phenol are not catalyzed by CIP. Horseradish peroxidase (HRP) is a kind of plant peroxidase which also catalyzes alkyl phenol compounds. The substrate specificity spectrum of HRP is narrower than CIP : HRP cannot catalyze o-isopropyl phenol, o-tert-butyl phenol,
and m-tert-butyl phenol. Also, the yield of m-isopropyl phenol is very low. This was confirmed from the docking result that the yield is higher, and docking distance is closer. In this presentation, docking energy and distance between Fe atom in heme group and oxygen atom in phenol compounds were calculated. And the relationships between Mn (number-average molecular weight), yield, docking energy and distance were investigated by QSAR methods. It was found that there is a linear relationship among docking energy, docking distance and the yield.

저자

• Jong Chul Park [ School of Chemical and Biological Engineering, Seoul National University ]
• Young Je Yoo [ School of Chemical and Biological Engineering, Seoul National University ]
• Yong Hwan Kim [ Department of Chemical Engineering, Kwangwoon University ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576