Hyejin Hwang, So Hyun Kim, Seong-won Nam, Sungsu Park
언어
영어(ENG)
URL
https://www.earticle.net/Article/A98590
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
The chemotaxis of C.elegans has been conventionally studied by analyzing their movements toward attractant gradient on agar plates. Since the gradient was generated by diffusion of the attractant through porous agar, its concentration profile is ever changing. Thus, it needs to build consistent chemical gradient to perform accurate chemotaxis. Herein, we describe a PDMS (polydimethyl siloxane) microfluidic device which consists of a gradient-generating portion [1] and array of posts. Posts help worms swimming in water by enhancing their motility via mechanosensational reflex upon their bumping to the posts. Using this device, we were able to observe C. elegans swimming up the attractant gradient or down the repellent gradient. Moreover the device with linear gradient provides a sensitive platform to investigate chemo-response.
저자
Hyejin Hwang [ Division of Nano Sciences (BK 21), Ewha Womans University ]
So Hyun Kim [ Division of Nano Sciences (BK 21), Ewha Womans University ]
Seong-won Nam [ Division of Nano Sciences (BK 21), Ewha Womans University ]
Sungsu Park [ Division of Nano Sciences (BK 21), Ewha Womans University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동