Earticle

초록

영어

Great interests have been emerged in the development of bioelectronic devices which performed functions realized by current silicon based semiconductor devices because of their compatibilities for organic-inorganic interconnections or networks. Therefore the purpose of this study is to develop artificial molecular memory devices by biomimetic approach using metalloproteins. we fabricated a biomemory device that includes a recombinant azurin with a cysteine residue modified by site-directed mutagenesis technique [1]. Functional azurin proteins
developed in this study were covalently-immobilized on four different Au electrodes patterned on a single Si substrate. The redox property of Azurin molecules on individual electrodes was measured by cyclic voltammetry (CV) experiments, respectively. Using open circuit potential amperometry (OCPA) method the memory function of the fabricated biodevice was confirmed. Upon applying particular oxidation voltage to Au electrode causes that particular protein layer becomes oxidized and stores positive charge which is represented as memory write (bit of “1”) and rest of the protein molecules on other electrodes are in its original state (bit of “0”). The memory read and erase functions are achieved by the application of open circuit and reduction potentials respectively. Applying oxidation potentials in different combinations bit of information can be stored in to the azurin molecules. Finally, based on the measurements of the charging currents of the fabricated biomemeory device, it is likely to be the key in the development of molecular/semiconductor electronic devices.

저자

• Ajay Kumar Yagati [ Interdisciplinary Program of Integrated Biotechnology, Sogang University ]
• Sang-Uk Kim [ Interdisciplinary Program of Integrated Biotechnology, Sogang University ]
• Cheol-Heon Yea [ Department of Chemical & Biomolecular Engineering, Sogang University ]
• Da-Yeon Kang [ Department of Chemical & Biomolecular Engineering, Sogang University ]
• Junhong Min [ College of Bionanotechnology, Kyungwon University ]
• Jeong-Woo Choi [ 1Interdisciplinary Program of Integrated Biotechnology, Sogang University, 2Department of Chemical & Biomolecular Engineering, Sogang University ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576