Earticle

초록

영어

The water extract of Saururus chinensis was investigated for oxygen radical absorbance capacity (ORAC),reducing capacity, metal chelating activity, and intracellular antioxidant activity using HepG2 cell. When 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) was used for the generation of peroxyl radicals in vitro, S. chinensis extract (SC-E)showed the strong and concentration-dependent scavenging activity through donating protons which could be explained by itsreducing property. When hydroxyl radicals were generated in vitro through the addition of Cu2+ and H2O2, SC-E demonstratedthe antioxidant activity depending on its concentration. In HepG2 cell model, most of intracellular oxidative stress generatedby AAPH was efficiently removed by SC-E. However, when Cu2+ without H2O2 was used as an oxidant in the intracellularassay, SC-E partially reduced the oxidative stress caused by Cu2+ in cellular antioxidant activity assay system. These resultsindicate that SC-E could be utilized for the development of functional foods as antioxidant resource in the near future.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

저자

• Gyo-Nam Kim [ Department of Food and Nutrition, Hannam University, Daejeon 306-791, Korea ]
• Jung-Sook Lee [ Department of Food and Nutrition, Hannam University, Daejeon 306-791, Korea ]
• Hae-Dong Jang [ Department of Food and Nutrition, Hannam University, Daejeon 306-791, Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664