Earticle

현재 위치 Home

Research Articles

Anti-platelet Activity of Tissue-cultured Mountain Ginseng Adventitious Roots in Human Whole Blood

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 17 Number 6 (2008.12)바로가기
  • 페이지
    pp.1197-1202
  • 저자
    Won Kyung Jeon, Bo Kyung Yoo, Yeong Eun Kim, Sun Ok Park, Byoung Seob Ko, Eun-Joo Hahn, Kee-Yoeup Paek
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A98196

※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

원문정보

초록

영어
Present study investigated the effects of the 70% ethanol extracts of tissue-cultured mountain ginseng (TCMG),Korean red ginseng (KRG), and Panax ginseng (PG) on agonist-induced platelet aggregation and activation in human wholeblood. The IC50 values for TCMG, KRG, and PG were 1.159, 3.695, and 4.978mg/mL for collagen-induced aggregation,0.820, 2.030, and 4.743 mg/mL for arachidonic acid-induced aggregation, and 1.070, 2.617, and 2.954mg/mL for ADP-induced aggregation, respectively. Also, this study assessed the effects of the most active extract, TCMG, on markers ofplatelet activation by determining receptor expression on platelet membranes in healthy subjects, including expression ofGPIIb/IIIa-like (PAC-1) and P-selectin (CD62), by flow cytometry. A significant decrease in PAC-1 expression (p=0.018) wasobserved in the presence of TCMG. These results show that TCMG has potent anti-platelet activity.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

저자

  • Won Kyung Jeon [ Department of Herbal Resources Research, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea ]
  • Bo Kyung Yoo [ Herbal Quality Control Team, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea ]
  • Yeong Eun Kim [ Herbal Quality Control Team, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea ]
  • Sun Ok Park [ Herbal Quality Control Team, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea ]
  • Eun-Joo Hahn [ Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Chungbuk 361-763, Korea ]
  • Kee-Yoeup Paek [ Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Chungbuk 361-763, Korea ]
  • Byoung Seob Ko [ Herbal Quality Control Team, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 17 Number 6

    피인용수 : 0(자료제공 : 네이버학술정보)

    함께 이용한 논문 이 논문을 다운로드한 분들이 이용한 다른 논문입니다.

      페이지 저장