Earticle

초록

영어

The effect of some peptides on hepatoprotection and cecal fermentation against D-galactosamine (GalN)-treatedrats was studied. In acute hepatic injury tests, serum alanine aminotransferase (ALT), aspartate aminotranferase (AST), andlactic dehydrogenase (LDH) activities were remarkably increased after injection of GalN. However, potato and soybeanpeptides significantly decreased GalN-induced alterations of serum ALT and AST activities. Hepatic thiobarbituric acid-reactive substance (TBARS) concentration in GalN-treated groups fed potato and soybean peptides was significantly lowerthan that in GalN-treated control group. Hepatic glutathione level in the GalN-treated group fed potato peptide wassignificantly higher than that in GalN-treated control group. Furthermore, cecal Lactobacillus level in GalN-treated groups fedpotato and soybean peptides was significantly higher than that in GalN-treated control group, and cecal short-chain fatty acidconcentrations in GalN-treated group fed potato peptide were significantly higher than in GalN-treated control group. Theseresults indicate that potato peptide may improve the cecal fermentation and prevent the GalN-induced liver damage in rats.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

저자

• Kiyoshi Ohba [ Hokkaido Tokachi Area Regional Food Processing Technology Center, Obihiro, Hokkaido 080-2462, Japan ]
• Kyu-Ho Han [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ]
• Ruvini Liyanage [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ]
• Megumi Nirei [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ]
• Naoto Hashimoto [ Department of Upland Agriculture, National Agricultural Research Center for Hokkaido Region, Memuro, Hokkaido 082-0071, Japan ]
• Ken-ichiro Shimada [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ]
• Mitsuo Sekikawa [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ]
• Keiko Sasaki [ Hokkaido Tokachi Area Regional Food Processing Technology Center, Obihiro, Hokkaido 080-2462, Japan ]
• Chi-Ho Lee [ Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 143-701, Korea ]
• Michihiro Fukushima [ Department of Agriculture and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664