Earticle

초록

영어

Drugs are often taken together with meals and there are numerous opportunity for food-drug interaction to occure. Food-drug interactions and their clinical consequences are very complex indeed. The composition of the meal, and the volume of fluid that is ingested often are decisive factors in food-drug interactions. Various formulations of a specific drug may behave differently. Solutions and suspensions seem to be less susceptible and enteric-coated preparations are more susceptible, to food interactions than are other dosage forms but exceptions to this rule do exist. Furthermore, generic and environmental factors, disease and other drugs cause considerable inter- and intraindividual variation in food-drug interactions. Also, eating habits are dissimilar in different parts of the world, and diets often vary greatly from day to day. The taking of drugs together with meals offers some obvious benefits. It may help to reduce gastrointestinal irritation and compliance is improved. On the other hand, in some cases food interferes seriously with drug absorption. The purpose of this review is to clarify the complexity of food-drug interactions, and to discuss interactions that may be of clinical importance.

목차

영문요약
 위장관(enteral)을 통한 흡수에 영향을 주는 인자
 음식물에 의한 흡수 영향
 음식물 구성 성분에 따른 약물의 흡수 및 대사 영향
 결론
 참고문헌

키워드

저자

• 윤휘열 [ Hwi-yeol Yun | 충남대학교 약학대학 임상약학 연구실 ]
• 백민선 [ Min-sun Baek | 식품의약품 안전청 의약품 동등성 평가과 ]
• 권광일 [ Kwang-il Kwon | 충남대학교 약학대학 임상약학 연구실 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615