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Anti-Helicobacter pylori, Cytotoxic, and Anti-inflammatory Activities of White Ginseng Extract

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 17 Number 5 (2008.10)바로가기
  • 페이지
    pp.1106-1109
  • 저자
    Hee-Sook Jee, Kyung-Hoon Chang, Sun-Hee Moon, Se-Ho Park, Hyun-Dong Paik
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A88442

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원문정보

초록

영어
The anti-Helicobacter pylori activity, cytotoxicity, and anti-inflammatory activity of white ginseng extract (WGE) were investigated in vitro in this study. The antimicrobial effects of WGE toward H. pylori strains 52 J99, SSI, and 51 were tested using the disk diffusion method. Among these H. pylori strains, H. pylori 52 was the most sensitive, having the largest inhibition zone (19 mm), followed by J99, SSI, and 51. The zone of inhibition due to WGE increased significantly with
increasing dosage. The cytotoxicity of WGE toward the human cancer cell lines A-549 (human lung carcinoma), HEC-1-B (human endometrial adenocarcinoma), HeLa (human uterin adenocarcinoma), and SW-156 (human kidney carcinoma) was measured using the 3-(4,5-dimethylthizol-2-yl)-2,5-diphenylate-tetrazolium bromide (MTT) assay. WGE exhibited an inhibitory effect on cell growth at 2.0 mg/mL for all tumor cell lines. An analysis of anti-inflammatory activity using the RAW 264.7 cell line showed that the inhibition of nitric oxide (NO) production increased as the WGE content increased. These results demonstrate the potential of WGE to be used as a health-promoting substance.

목차

Abstract
 Introduction
 Materials and Methods
  Materials
  Bacterial strains
  Cell lines and culture conditions
  Nitrite assay
 Results and Discussion
  Anti-H. pylori activity
  Cytotoxic effects of WGE
  Anti-inflammatory activity of WGE
 References

키워드

white ginseng extract Helicobacter pylori anti-Helicobacter pylori activity cytotoxicity anti-inflammatory activity

저자

  • Hee-Sook Jee [ Division of Animal Life Science, Konkuk University ]
  • Kyung-Hoon Chang [ Division of Animal Life Science, Konkuk University ]
  • Sun-Hee Moon [ Division of Animal Life Science, Konkuk University ]
  • Se-Ho Park [ Dongwon Korean Ginseng Co., Ltd., ]
  • Hyun-Dong Paik [ Division of Animal Life Science, Konkuk University ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 17 Number 5

    피인용수 : 0(자료제공 : 네이버학술정보)

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